Article Information
- Received June 10, 2018
- Revision received July 4, 2018
- Accepted July 6, 2018
- Published online July 16, 2018.
Author Information
- Barbara Baldo1,*,
- Muhammad Umar Sajjad1,*,
- Rachel Y. Cheong1,
- Julie Bigarreau2,3,
- Ravi Vijayvargia4,5,*,
- Catriona McLean6,
- Anselme L. Perrier2,3,
- Ihn Sik Seong4,5,
- Glenda Halliday7,
- Åsa Petersén1 and
- Deniz Kirik8
- 1Translational Neuroendocrine Research Unit, Department of Experimental Medical Science, Lund University, Lund 22184, Sweden BMC D11
- 2Institut National De La Santé Et De La Recherche Médicale UMR861, I-Stem, AFM, Corbeil-Essonnes 91100, France
- 3UEVE UMR861, I-STEM, AFM, Corbeil-Essonnes 91100, France
- 4Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA
- 5Department of Neurology, Harvard Medical School, Boston, MA
- 6Department of Pathology, Alfred Hospital, Melbourne, Victoria, Australia
- 7Sydney Medical School, Brain & Mind Centre, the University of Sydney, Camperdown, NSW 2050, UNSW Medicine & NeuRA, Kensington, NSW 2052, Australia
- 8Brain Repair and Imaging in Neural Systems, Department of Experimental Medical Science, Lund University, Lund 22184, Sweden BMC D11
- Correspondence should be addressed to Deniz Kirik, BRAINS Unit, Department of Experimental Medical Science, Lund University, BMC D11, 22184, Lund, Sweden. E-mail: deniz.kirik{at}med.lu.se[MAIL]
Author contributions
Author contributions: BB, MUS, ÅP, and DK designed research; BB, MUS, RYC, and JB performed research; RV, CM, ALP, ISS, and GH contributed unpublished reagents/analytic tools; BB, MUS, DK, and ÅP analyzed data; BB, ÅP, and DK wrote the paper.
Disclosures
The authors declare no competing financial interests.
This work was supported in part by the Swedish Research Council [K2013-62X-21398-04-4, K2011-61P-20945-01-3, K2014-62X-20404-08-5 to D.K. and A.P.], Region of Skane ALF grants to DK and AP, Royal Physiographic Society of Lund to BB, National Institutes of Health/National Institute of Neurological Disorders and Stroke [R01 NS079651 to I.S.S], the Agence Nationale pour la Recherche, the JPND program on ModelPolyQ, Neuratris (Grant Q5 ‘‘Investment for the future’’ ANR-11-INBS-0011), the Laboratoire d’Excellence Revive (Investissement d’Avenir; ANR-10-LABX-73), the French National Health Institute (INSERM), and the AFM-Téléthon (Association Française contre les Myopathies) to A.L.P. J.B is supported by a fellowship the Laboratoire d’Excellence Revive (Investissement d’Avenir; ANR-10-LABX-73). Human brain tissue samples were received from the Sydney Brain Bank, which is supported by Neuroscience Research Australia and the University of New South Wales, and from the Victorian Brain Bank Network, supported by the Mental Health Research Institute, Alfred Hospital, Victorian Forensic Institute of Medicine, The University of Melbourne, Helen Macpherson Smith Trust, Parkinson’s Victoria and Perpetual Philanthropic Service. G.M.H. is a National Health and Medical Research Council of Australia Senior Principal Research Fellow (#1079679).
Funding
Vetenskapsrådet (VR)
K2013-62X-21398-04-4; K2011-61P-20945-01-3; K2014-62X-20404-08-5Region Skåne ALF
Kungliga Fysiografiska Sällskapet i Lund (Royal Physiographic Society in Lund)
HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)
R01 NS079651Agence Nationale de la Recherche (ANR)
ANR-11-INBS-0011; ANR-10-LABX-73Institut National de la Santé et de la Recherche Médicale (Inserm)
AFM-Téléthon (French Muscular Dystrophy Association)
Neuroscience research Australia and the University of New South Wales
Mental health research institute, Alfred Hospital, Victorian Forensic Institute of Medicine
The University of Melbourne, Helen Macpherson Smith Trust, Parkinson's Victoria and Perpetual Philantropic Service
Department of Health | National Health and Medical Research Council (NHMRC)
1079679
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