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Research ArticleNew Research, Cognition and Behavior

Differential Involvement of Kinase Activity of Ca2+/Calmodulin-Dependent Protein Kinase IIα in Hippocampus- and Amygdala-Dependent Memory Revealed by Kinase-Dead Knock-In Mouse

Yoko Yamagata, Yuchio Yanagawa and Keiji Imoto
eNeuro 7 August 2018, 5 (4) ENEURO.0133-18.2018; https://doi.org/10.1523/ENEURO.0133-18.2018
Yoko Yamagata
1Division of Neural Signaling, National Institute for Physiological Sciences, Okazaki 444-8787, Japan
2SOKENDAI (The Graduate University for Advanced Studies), Okazaki 444-8787, Japan
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Yuchio Yanagawa
3Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan
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Keiji Imoto
1Division of Neural Signaling, National Institute for Physiological Sciences, Okazaki 444-8787, Japan
2SOKENDAI (The Graduate University for Advanced Studies), Okazaki 444-8787, Japan
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0133-18.2018
PubMed 
30225347
Published By 
Society for Neuroscience
History 
  • Received April 5, 2018
  • Revision received July 23, 2018
  • Accepted July 27, 2018
  • Published online August 7, 2018.
Copyright & Usage 
Copyright © 2018 Yamagata et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Yoko Yamagata1,2,
  2. Yuchio Yanagawa3 and
  3. Keiji Imoto1,2
  1. 1Division of Neural Signaling, National Institute for Physiological Sciences, Okazaki 444-8787, Japan
  2. 2SOKENDAI (The Graduate University for Advanced Studies), Okazaki 444-8787, Japan
  3. 3Department of Genetic and Behavioral Neuroscience, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan
  1. Correspondence should be addressed to Dr. Yoko Yamagata, Division of Neural Signaling, National Institute for Physiological Sciences, Myodaiji, Okazaki 444-8787, Japan, E-mail: yamagata{at}nips.ac.jp.
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Author contributions

  1. Author contributions: Y.Yam. designed research; Y.Yam performed research; Y.Yan. and K.I. contributed unpublished reagents/analytic tools; Y.Yam analyzed data; Y.Yam. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported in part by Grants-in-Aid for Scientific Research from Japan Society for the Promotion of Science (KAKENHI) 22500301 and 16K08511 (to Y.Yam.) and 26290002, 15H05872, and 17H05550 (to Y.Yan.).

Funding

  • Japan Society for the Promotion of Science (JSPS)

    22500301; 16K08511; 26290002; 15H05872; 17H05550

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  • You are viewing the most recent version of this article.
  • previous version (August 07, 2018).

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Aug 20185489787
Sep 201832215364
Oct 20189218023
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Apr 20197428
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Jun 20211479
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Total 202112631144
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Apr 202213210
May 202214412
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Jul 202577130
Aug 202595320
Sep 202579716
Oct 2025125914
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Dec 202598421
Total 202576785193
Jan 20264647
Total 20264647
Total131148061310
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Differential Involvement of Kinase Activity of Ca2+/Calmodulin-Dependent Protein Kinase IIα in Hippocampus- and Amygdala-Dependent Memory Revealed by Kinase-Dead Knock-In Mouse
Yoko Yamagata, Yuchio Yanagawa, Keiji Imoto
eNeuro 7 August 2018, 5 (4) ENEURO.0133-18.2018; DOI: 10.1523/ENEURO.0133-18.2018

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Differential Involvement of Kinase Activity of Ca2+/Calmodulin-Dependent Protein Kinase IIα in Hippocampus- and Amygdala-Dependent Memory Revealed by Kinase-Dead Knock-In Mouse
Yoko Yamagata, Yuchio Yanagawa, Keiji Imoto
eNeuro 7 August 2018, 5 (4) ENEURO.0133-18.2018; DOI: 10.1523/ENEURO.0133-18.2018
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Keywords

  • calmodulin kinase II
  • fear conditioning
  • knock-in mouse
  • phosphorylation
  • PTSD
  • water maze

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