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Research ArticleMethods/New Tools, Novel Tools and Methods

Tetrode Recording from the Hippocampus of Behaving Mice Coupled with Four-Point-Irradiation Closed-Loop Optogenetics: A Technique to Study the Contribution of Hippocampal SWR Events to Learning

Dámaris K. Rangel Guerrero, James G. Donnett, Jozsef Csicsvari and Krisztián A. Kovács
eNeuro 27 August 2018, 5 (4) ENEURO.0087-18.2018; DOI: https://doi.org/10.1523/ENEURO.0087-18.2018
Dámaris K. Rangel Guerrero
1Institute of Science and Technology, Klosterneuburg 3400, Austria
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James G. Donnett
2Axona Ltd, St Albans AL3 6PA, United Kingdom
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Jozsef Csicsvari
1Institute of Science and Technology, Klosterneuburg 3400, Austria
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Krisztián A. Kovács
1Institute of Science and Technology, Klosterneuburg 3400, Austria
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0087-18.2018
PubMed 
30225344
Published By 
Society for Neuroscience
History 
  • Received March 5, 2018
  • Revision received July 8, 2018
  • Accepted July 20, 2018
  • Published online August 27, 2018.
Copyright & Usage 
Copyright © 2018 Rangel Guerrero et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Dámaris K. Rangel Guerrero1,
  2. James G. Donnett2,
  3. Jozsef Csicsvari1 and
  4. Krisztián A. Kovács1
  1. 1Institute of Science and Technology, Klosterneuburg 3400, Austria
  2. 2Axona Ltd, St Albans AL3 6PA, United Kingdom
  1. Correspondence should be addressed to Dr. Krisztián A. Kovács at The Institute of Science and Technology, Klosterneuburg 3400, Austria. E-mail: kkovacs.ist{at}t-online.hu.
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Author contributions

  1. Author contributions: K.A.K. and J.C. designed research; K.A.K. and D.K.R.G. performed research; K.A.K. and J.G.D. contributed unpublished reagents/analytic tools; K.A.K. and J.C. wrote the paper.

Disclosures

  • J.G.D. is affiliated to Axona Ltd, a company producing microdrives; however, J.G.D. was exclusively involved in the multi-step procedure of designing the microdrive and did not participate in the design of the experiments, data collection, and data analysis, and, correspondingly, did not exert any influence on the outcome of the experiments. All other authors declare no competing financial interests.

  • This work was supported by the Institute of Science and Technology Fellowship awarded to K.A.K. (Project: P IST EU01 under Research Executive Agency Grant 291734) and by the Austrian Science Fund (FWF01_I2072).

Funding

  • IST fellowship

    291734

Other Version

  • previous version (August 27, 2018).
  • You are viewing the most recent version of this article.

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Mar 20191318923
Apr 20191222927
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Total161649441303
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Tetrode Recording from the Hippocampus of Behaving Mice Coupled with Four-Point-Irradiation Closed-Loop Optogenetics: A Technique to Study the Contribution of Hippocampal SWR Events to Learning
Dámaris K. Rangel Guerrero, James G. Donnett, Jozsef Csicsvari, Krisztián A. Kovács
eNeuro 27 August 2018, 5 (4) ENEURO.0087-18.2018; DOI: 10.1523/ENEURO.0087-18.2018

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Tetrode Recording from the Hippocampus of Behaving Mice Coupled with Four-Point-Irradiation Closed-Loop Optogenetics: A Technique to Study the Contribution of Hippocampal SWR Events to Learning
Dámaris K. Rangel Guerrero, James G. Donnett, Jozsef Csicsvari, Krisztián A. Kovács
eNeuro 27 August 2018, 5 (4) ENEURO.0087-18.2018; DOI: 10.1523/ENEURO.0087-18.2018
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Keywords

  • hippocampus
  • learning
  • memory
  • multi-unit recording
  • optogenetics
  • sharp-wave ripple

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