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Research ArticleNew Research, Sensory and Motor Systems

Combinatorial Expression of Grp and Neurod6 Defines Dopamine Neuron Populations with Distinct Projection Patterns and Disease Vulnerability

Daniel J. Kramer, Davide Risso, Polina Kosillo, John Ngai and Helen S. Bateup
eNeuro 21 May 2018, 5 (3) ENEURO.0152-18.2018; https://doi.org/10.1523/ENEURO.0152-18.2018
Daniel J. Kramer
1Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720
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Davide Risso
3Division of Biostatistics and Epidemiology, Department of Healthcare Policy and Research, Weill Cornell Medicine, New York, NY 10065
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Polina Kosillo
1Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720
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John Ngai
1Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720
2Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720
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Helen S. Bateup
1Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720
2Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0152-18.2018
PubMed 
30135866
Published By 
Society for Neuroscience
History 
  • Received April 16, 2018
  • Accepted May 14, 2018
  • Published online May 21, 2018.
Copyright & Usage 
Copyright © 2018 Kramer et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Daniel J. Kramer1,
  2. Davide Risso3,
  3. Polina Kosillo1,
  4. John Ngai1,2 and
  5. Helen S. Bateup1,2
  1. 1Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720
  2. 2Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720
  3. 3Division of Biostatistics and Epidemiology, Department of Healthcare Policy and Research, Weill Cornell Medicine, New York, NY 10065
  1. Correspondence should be addressed to: Helen S. Bateup, Dept. of Molecular and Cell Biology, University of California, Berkeley, 142 Life Sciences Addition, Berkeley, CA 94720-3200. Email: bateup{at}berkeley.edu.
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Author contributions

  1. Author contributions: D.J.K., D.R., J.N., and H.S.B. designed research; D.J.K. and P.K. performed research, D.J.K, D.R., and H.S.B. analyzed data; D.J.K. and H.S.B. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by an NIMH Brain Initiative grant and supplement to J.N. (U01MH105979 H.S.B. Co-Investigator). H.S.B. is supported by a fellowship from the Alfred P. Sloan Foundation (FR-2015-65790) and a NARSAD Young Investigator Grant from the Brain & Behavior Research Foundation (25073).

Funding

  • HHS | NIH | National Institute of Mental Health (NIMH)

    U01MH105878
  • Alfred P. Sloan Foundation

    FR-2015-65790
  • Brain and Behavior Research Foundation (Brain & Behavior Research Foundation)

    25073

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  • You are viewing the most recent version of this article.
  • previous version (May 21, 2018).

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AbstractFullPdf
May 20183490123
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Mar 20191012923
Apr 2019910720
May 2019139846
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Jan 202078533
Feb 202066730
Mar 202034117
May 202068667
Jun 202056525
Jul 202023621
Aug 202023323
Sep 202065736
Oct 202038324
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Total 202045736334
Jan 202148725
Feb 202116613
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May 20213557
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Aug 202118226
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Apr 202208337
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Jul 202226826
Aug 202234928
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Feb 202324816
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May 202334121
Jun 202314210
Jul 202355522
Aug 2023126039
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Total 2024100979297
Jan 202597828
Feb 202519819
Mar 202559734
Apr 202548924
May 202588617
Jun 2025199530
Jul 2025105036
Total 202556593188
Total135763452554
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May/June 2018
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Combinatorial Expression of Grp and Neurod6 Defines Dopamine Neuron Populations with Distinct Projection Patterns and Disease Vulnerability
Daniel J. Kramer, Davide Risso, Polina Kosillo, John Ngai, Helen S. Bateup
eNeuro 21 May 2018, 5 (3) ENEURO.0152-18.2018; DOI: 10.1523/ENEURO.0152-18.2018

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Combinatorial Expression of Grp and Neurod6 Defines Dopamine Neuron Populations with Distinct Projection Patterns and Disease Vulnerability
Daniel J. Kramer, Davide Risso, Polina Kosillo, John Ngai, Helen S. Bateup
eNeuro 21 May 2018, 5 (3) ENEURO.0152-18.2018; DOI: 10.1523/ENEURO.0152-18.2018
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Keywords

  • dopamine Neurons
  • Grp
  • Neurod6
  • Retrograde Tracing
  • single-cell RNA-sequencing
  • VTA
  • Cellular Heterogeneity

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