Article Information
- Received December 5, 2017
- Revision received March 8, 2018
- Accepted April 6, 2018
- Published online April 27, 2018.
Author Information
- Rosalind Brown1,*,
- Alice D. Lam2,3,*,
- Alfredo Gonzalez-Sulser1,*,
- Andrew Ying1,
- Mary Jones1,
- Robert Chang-Chih Chou1,
- Makis Tzioras1,
- Crispin Y. Jordan1,
- Izabela Jedrasiak-Cape1,
- Anne-Laure Hemonnot4,
- Maurice Abou Jaoude2,3,
- Andrew J. Cole2,3,
- Sydney S. Cash2,3,
- Takashi Saito5,
- Takaomi Saido5,
- Richard R. Ribchester1,
- Kevan Hashemi6 and
- Iris Oren1
- 1Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, EH8 9JZ, United Kingdom
- 2Epilepsy Division, Dept of Neurology, Massachusetts General Hospital, Boston, MA 02214
- 3Harvard Medical School, Boston, MA 02214
- 4Université de Montpellier, Montpellier, 34000 France
- 5Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Saitama, 351-0198 Japan
- 6OpenSource Instruments Inc, Watertown, MA 02472
- Correspondence should be addressed to Iris Oren, Centre for Discovery Brain Sciences, University of Edinburgh, 1 George Square, Edinburgh EH8 9JZ, United Kingdom, E-mail: iris.oren{at}ed.ac.uk.
Author contributions
Author contributions: R.B., R.R.R., and I.O. designed research; R.B., A.D.L., A.G.-S., M.J., R.C.-C.C., I.J.-C., A.-L.H., T.Saito, and T.Saido performed research; M.A.J., A.J.C., S.S.C., and K.H. contributed unpublished reagents/analytic tools; A.D.L., A.Y., R.C.-C.C., M.T., C.Y.J., A.-L.H., and I.O. analyzed data; R.B., A.D.L., K.H., and I.O. wrote the paper.
↵* R.B., A.D.L., and A.G.-S. contributed equally to this work.
Disclosures
The authors declare no competing financial interests.
I.O. was supported by the Alzheimer’s Society Grant PG-2012-208, the RS Macdonald Charitable Trust, The Muir Maxwell Epilepsy Centre, The Euan MacDonald Centre, and The Patrick Wild Centre; A.D.L. was supported by the American Academy of Neurology Institute; A.G.S. was supported by Epilepsy Research UK (Grant number: F1603); R.C.-C.C. was supported by the MRC Grant MR/M024075/1 awarded to R.R.R.
Funding
Alzheimer's Society
PG-2012-208RS Macdonald Charitable Trust
Muir Maxwell Epilepsy Centre
Euan MacDonald Centre
Patrick Wild Centre
American Academy of Neurology (AAN)
Epilepsy Research UK (ERUK)
Medical Research Council (MRC)
MR/M024075/1
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