Skip to main content

Umbrella menu

  • SfN.org
  • eNeuro
  • The Journal of Neuroscience
  • Neuronline
  • BrainFacts.org

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Latest Articles
    • Issue Archive
    • Editorials
    • Research Highlights
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • EDITORIAL BOARD
  • BLOG
  • ABOUT
    • Overview
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SfN.org
  • eNeuro
  • The Journal of Neuroscience
  • Neuronline
  • BrainFacts.org

User menu

  • My alerts

Search

  • Advanced search
eNeuro
  • My alerts

eNeuro

Advanced Search

Submit a Manuscript
  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Latest Articles
    • Issue Archive
    • Editorials
    • Research Highlights
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • EDITORIAL BOARD
  • BLOG
  • ABOUT
    • Overview
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
PreviousNext
Research ArticleNegative Results, Sensory and Motor Systems

Metabotropic Glutamate Receptor 2/3 (mGluR2/3) Activation Suppresses TRPV1 Sensitization in Mouse, But Not Human, Sensory Neurons

Tayler D. Sheahan, Manouela V. Valtcheva, Lisa A. McIlvried, Melanie Y. Pullen, David A.A. Baranger and Robert W. Gereau IV
eNeuro 5 March 2018, 5 (2) ENEURO.0412-17.2018; DOI: https://doi.org/10.1523/ENEURO.0412-17.2018
Tayler D. Sheahan
1Washington University Pain Center and Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri 63110
2Washington University Program in Neuroscience, Washington University School of Medicine, St. Louis, Missouri 63110
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Tayler D. Sheahan
Manouela V. Valtcheva
1Washington University Pain Center and Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri 63110
2Washington University Program in Neuroscience, Washington University School of Medicine, St. Louis, Missouri 63110
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lisa A. McIlvried
1Washington University Pain Center and Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri 63110
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Lisa A. McIlvried
Melanie Y. Pullen
1Washington University Pain Center and Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri 63110
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
David A.A. Baranger
2Washington University Program in Neuroscience, Washington University School of Medicine, St. Louis, Missouri 63110
3BRAIN Laboratory, Department of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, Missouri 63130
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for David A.A. Baranger
Robert W. Gereau IV
1Washington University Pain Center and Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri 63110
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Robert W. Gereau IV
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/ENEURO.0412-17.2018
PubMed 
29662945
Published By 
Society for Neuroscience
History 
  • Received November 29, 2017
  • Revision received February 6, 2018
  • Accepted February 7, 2018
  • Published online March 5, 2018.
Copyright & Usage 
Copyright © 2018 Sheahan et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Tayler D. Sheahan1,2,
  2. Manouela V. Valtcheva1,2,
  3. Lisa A. McIlvried1,
  4. Melanie Y. Pullen1,
  5. David A.A. Baranger2,3 and
  6. Robert W. Gereau IV1
  1. 1Washington University Pain Center and Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri 63110
  2. 2Washington University Program in Neuroscience, Washington University School of Medicine, St. Louis, Missouri 63110
  3. 3BRAIN Laboratory, Department of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, Missouri 63130
  1. Correspondence should be addressed to Robert W. Gereau IV, PhD, Director | Washington University Pain Center, Dr. Seymour and Rose T. Brown Professor, Department of Anesthesiology, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8054, St. Louis, MO 63110, Telephone number: (314) 362-8312, Fax Number: (314) 362-8334, E-mail: gereaur{at}wustl.edu.
View Full Text

Author contributions

  1. Author contributions: T.D.S. and R.W.G. IV designed research; T.D.S., M.V.V., L.A.M., and M.Y.P. performed research; T.D.S. and D.A.A.B. analyzed data; T.D.S. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • Conflict of Interest: Authors report no conflict of interest.

  • This work was supported by NINDS R01NS042595 to RWG, NINDS F31NS089130 to MVV, NIDA 2T32 DA007261-26 to LAM, and NSF DGE1745038 to DAAB.

Funding

  • HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)

    R01NS042595; F31NS089130
  • HHS | NIH | National Institute on Drug Abuse (NIDA)

    2T32 DA007261-26
  • NSF | EHR | Division of Graduate Education (DGE)

    DGE1745038

Other Version

  • previous version (March 05, 2018).
  • You are viewing the most recent version of this article.

Statistics from Altmetric.com

Article usage

Select a custom date range for the past year
E.g., 2021-04-13
to
E.g., 2021-04-13

Article usage: March 2018 to April 2021

AbstractFullPdf
Mar 20187520147
Apr 20181849881
May 20181187844
Jun 2018466744
Jul 2018369638
Aug 2018348036
Sep 2018364024
Oct 20184217337
Nov 20183222623
Dec 20182821421
Total 201813081072495
Jan 20191620215
Feb 20192021113
Mar 20191312612
Apr 2019127012
May 201912549
Jun 201965221
Jul 201997022
Aug 201993923
Sep 201992612
Oct 201943410
Nov 201943612
Dec 201955214
Total 2019119972175
Jan 202056124
Feb 202003619
Mar 202044511
Apr 20204309
May 202033418
Jun 202053443
Jul 202023415
Aug 202034620
Sep 202084218
Oct 202068831
Nov 202037627
Dec 2020811034
Total 202051636269
Jan 202147919
Feb 202117812
Mar 202179416
Apr 20215257
Total 20211727654
Total14952956993
Back to top

In this issue

eneuro: 5 (2)
eNeuro
Vol. 5, Issue 2
March/April 2018
  • Table of Contents
  • Index by author
Email

Thank you for sharing this eNeuro article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Metabotropic Glutamate Receptor 2/3 (mGluR2/3) Activation Suppresses TRPV1 Sensitization in Mouse, But Not Human, Sensory Neurons
(Your Name) has forwarded a page to you from eNeuro
(Your Name) thought you would be interested in this article in eNeuro.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
Metabotropic Glutamate Receptor 2/3 (mGluR2/3) Activation Suppresses TRPV1 Sensitization in Mouse, But Not Human, Sensory Neurons
Tayler D. Sheahan, Manouela V. Valtcheva, Lisa A. McIlvried, Melanie Y. Pullen, David A.A. Baranger, Robert W. Gereau
eNeuro 5 March 2018, 5 (2) ENEURO.0412-17.2018; DOI: 10.1523/ENEURO.0412-17.2018

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Share
Metabotropic Glutamate Receptor 2/3 (mGluR2/3) Activation Suppresses TRPV1 Sensitization in Mouse, But Not Human, Sensory Neurons
Tayler D. Sheahan, Manouela V. Valtcheva, Lisa A. McIlvried, Melanie Y. Pullen, David A.A. Baranger, Robert W. Gereau
eNeuro 5 March 2018, 5 (2) ENEURO.0412-17.2018; DOI: 10.1523/ENEURO.0412-17.2018
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Significance Statement
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments
    • Footnotes
    • References
    • Synthesis
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • Dorsal root ganglia
  • glutamate
  • human neurons
  • Metabotropic
  • Nociceptors
  • Pain

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

Negative Results

  • Male goal-tracker and sign-tracker rats do not differ in neuroendocrine or behavioral measures of stress-reactivity
  • Closed-Loop Acoustic Stimulation Enhances Sleep Oscillations But Not Memory Performance
  • Cyfip1 Haploinsufficiency Does Not Alter GABAA Receptor δ-Subunit Expression and Tonic Inhibition in Dentate Gyrus PV+ Interneurons and Granule Cells
Show more Negative Results

Sensory and Motor Systems

  • Review of literatures: Physiology of Orofacial Pain in dentistry
  • Dynamics of glutamatergic drive underlie diverse responses of olfactory bulb outputs in vivo
  • A mechanistic model for reward prediction and extinction learning in the fruit fly
Show more Sensory and Motor Systems

Subjects

  • Sensory and Motor Systems
  • Home
  • Alerts
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Latest Articles
  • Issue Archive
  • Blog
  • Browse by Topic

Information

  • For Authors
  • For the Media

About

  • About the Journal
  • Editorial Board
  • Privacy Policy
  • Contact
  • Feedback
(eNeuro logo)
(SfN logo)

Copyright © 2021 by the Society for Neuroscience.
eNeuro eISSN: 2373-2822

The ideas and opinions expressed in eNeuro do not necessarily reflect those of SfN or the eNeuro Editorial Board. Publication of an advertisement or other product mention in eNeuro should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in eNeuro.