Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT

User menu

Search

  • Advanced search
eNeuro
eNeuro

Advanced Search

 

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT
PreviousNext
Research ArticleNew Research, Disorders of the Nervous System

BC RNA Mislocalization in the Fragile X Premutation

Ilham A. Muslimov, Taesun Eom, Anna Iacoangeli, Shih-Chieh Chuang, Renate K. Hukema, Rob Willemsen, Dimitre G. Stefanov, Robert K. S. Wong and Henri Tiedge
eNeuro 9 April 2018, 5 (2) ENEURO.0091-18.2018; https://doi.org/10.1523/ENEURO.0091-18.2018
Ilham A. Muslimov
1The Robert F. Furchgott Center for Neural and Behavioral Science, State University of New York Downstate Medical Center, Brooklyn, New York 11203
2Department of Physiology and Pharmacology, State University of New York Downstate Medical Center, Brooklyn, New York 11203
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Taesun Eom
1The Robert F. Furchgott Center for Neural and Behavioral Science, State University of New York Downstate Medical Center, Brooklyn, New York 11203
2Department of Physiology and Pharmacology, State University of New York Downstate Medical Center, Brooklyn, New York 11203
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Anna Iacoangeli
1The Robert F. Furchgott Center for Neural and Behavioral Science, State University of New York Downstate Medical Center, Brooklyn, New York 11203
2Department of Physiology and Pharmacology, State University of New York Downstate Medical Center, Brooklyn, New York 11203
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Anna Iacoangeli
Shih-Chieh Chuang
1The Robert F. Furchgott Center for Neural and Behavioral Science, State University of New York Downstate Medical Center, Brooklyn, New York 11203
2Department of Physiology and Pharmacology, State University of New York Downstate Medical Center, Brooklyn, New York 11203
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Renate K. Hukema
5Department of Clinical Genetics, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Renate K. Hukema
Rob Willemsen
5Department of Clinical Genetics, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Rob Willemsen
Dimitre G. Stefanov
3Statistical Design and Analysis, Research Division, State University of New York Downstate Medical Center, Brooklyn, New York 11203
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Robert K. S. Wong
1The Robert F. Furchgott Center for Neural and Behavioral Science, State University of New York Downstate Medical Center, Brooklyn, New York 11203
2Department of Physiology and Pharmacology, State University of New York Downstate Medical Center, Brooklyn, New York 11203
4Department of Neurology, State University of New York Downstate Medical Center, Brooklyn, New York 11203
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Henri Tiedge
1The Robert F. Furchgott Center for Neural and Behavioral Science, State University of New York Downstate Medical Center, Brooklyn, New York 11203
2Department of Physiology and Pharmacology, State University of New York Downstate Medical Center, Brooklyn, New York 11203
4Department of Neurology, State University of New York Downstate Medical Center, Brooklyn, New York 11203
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Henri Tiedge
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/ENEURO.0091-18.2018
PubMed 
29766042
Published By 
Society for Neuroscience
History 
  • Received March 8, 2018
  • Revision received March 20, 2018
  • Accepted March 27, 2018
  • Published online April 9, 2018.
Copyright & Usage 
Copyright © 2018 Muslimov et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Ilham A. Muslimov1,2,*,
  2. Taesun Eom1,2,*,
  3. Anna Iacoangeli1,2,*,
  4. Shih-Chieh Chuang1,2,*,
  5. Renate K. Hukema5,
  6. Rob Willemsen5,
  7. Dimitre G. Stefanov3,
  8. Robert K. S. Wong1,2,4 and
  9. Henri Tiedge1,2,4
  1. 1The Robert F. Furchgott Center for Neural and Behavioral Science, State University of New York Downstate Medical Center, Brooklyn, New York 11203
  2. 2Department of Physiology and Pharmacology, State University of New York Downstate Medical Center, Brooklyn, New York 11203
  3. 3Statistical Design and Analysis, Research Division, State University of New York Downstate Medical Center, Brooklyn, New York 11203
  4. 4Department of Neurology, State University of New York Downstate Medical Center, Brooklyn, New York 11203
  5. 5Department of Clinical Genetics, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands
  1. Correspondence should be addressed to Henri Tiedge, The Robert F. Furchgott Center for Neural and Behavioral Science, Department of Physiology and Pharmacology, SUNY Downstate Medical Center, 450 Clarkson Ave, Brooklyn, NY 11203. E-mail: henri.tiedge{at}downstate.edu.
  • Anna Iacoangeli’s present address is Tisch MS Research Center of New York, New York, New York 10019.

View Full Text

Author contributions

  1. Author contributions: IAM, TE, AI, and S-CC performed experiments, analyzed experimental results, and assembled illustrations. They also participated in the experimental design. RKH and RW provided CGG KI animals and guidance in animal colony maintenance and animal experimental routines including CGG-repeat length and FMRP brain level determination. DGS performed statistical analyses and provided statistical consultation. RKSW participated in the design and analysis of electrophysiology experiments. HT oversaw planning and execution of the research project, analyzed experimental data, and drafted the initial manuscript. All authors participated in the drafting, reviewing, and editing of the manuscript.

  2. ↵* I.A.M., T.E., A.I., and S.-C.C. contributed equally to this work.

  • Anna Iacoangeli’s present address is Tisch MS Research Center of New York, New York, New York 10019.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported in part by NIH grants DA026110 and NS046769 (HT).

Funding

  • NIH

    DA026110; NS046769

Other Version

  • You are viewing the most recent version of this article.
  • previous version (April 09, 2018).

Online Impact

 

Article usage

Select a custom date range for the past year
E.g., 2026-03-14
to
E.g., 2026-03-14

Article usage: April 2018 to March 2026

AbstractFullPdf
Apr 20184887280
May 201818627245
Jun 2018606945
Jul 201831228
Aug 2018183720
Sep 20189289
Oct 2018192816
Nov 201892812
Dec 201811234
Total 2018831579239
Jan 20199379
Feb 201981037
Mar 2019818713
Apr 201961834
May 201971396
Jun 201971058
Jul 20191120915
Aug 2019447510
Oct 201973829
Nov 2019728610
Dec 2019417214
Total 2019782278105
Jan 202085915
Feb 202044619
Mar 20203772
May 20203608
Jun 20200415
Jul 202021484
Aug 20206459
Sep 20202617
Oct 202059115
Nov 202037013
Dec 2020210611
Total 202038804108
Jan 202157511
Feb 20212643
Mar 202128115
Apr 20212837
May 20213887
Jun 202121376
Jul 2021212021
Aug 202118814
Sep 20210678
Oct 202108123
Nov 202127522
Dec 20211698
Total 2021221028145
Jan 20223717
Feb 20222597
Mar 20220649
Apr 20220597
May 202217217
Jun 20221685
Jul 202206412
Aug 202205911
Sep 202205018
Oct 202219915
Nov 202215111
Dec 2022106221
Total 202219778140
Jan 202310679
Feb 20230554
Mar 20230684
Apr 20230647
May 20232575
Jun 20233779
Jul 202337218
Aug 202377329
Sep 202316416
Oct 20230784
Nov 202311809
Dec 202348817
Total 202331943131
Jan 20240721
Feb 20242738
Mar 20244758
Apr 202437714
May 2024230212
Jun 20244849
Jul 202458110
Aug 202448513
Sep 202447915
Oct 202407811
Nov 20241703
Dec 202406611
Total 2024291142115
Jan 202537411
Feb 20251896
Mar 202508310
Apr 202507214
May 20253788
Jun 2025812023
Jul 202579922
Aug 202568325
Sep 2025916621
Oct 202599716
Nov 20251310116
Dec 2025812228
Total 2025671184200
Jan 2026111306
Feb 2026102768
Mar 20263365
Total 20262444219
Total113991781202
Back to top

In this issue

eneuro: 5 (2)
eNeuro
Vol. 5, Issue 2
March/April 2018
  • Table of Contents
  • Index by author
Email

Thank you for sharing this eNeuro article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
BC RNA Mislocalization in the Fragile X Premutation
(Your Name) has forwarded a page to you from eNeuro
(Your Name) thought you would be interested in this article in eNeuro.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
BC RNA Mislocalization in the Fragile X Premutation
Ilham A. Muslimov, Taesun Eom, Anna Iacoangeli, Shih-Chieh Chuang, Renate K. Hukema, Rob Willemsen, Dimitre G. Stefanov, Robert K. S. Wong, Henri Tiedge
eNeuro 9 April 2018, 5 (2) ENEURO.0091-18.2018; DOI: 10.1523/ENEURO.0091-18.2018

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Share
BC RNA Mislocalization in the Fragile X Premutation
Ilham A. Muslimov, Taesun Eom, Anna Iacoangeli, Shih-Chieh Chuang, Renate K. Hukema, Rob Willemsen, Dimitre G. Stefanov, Robert K. S. Wong, Henri Tiedge
eNeuro 9 April 2018, 5 (2) ENEURO.0091-18.2018; DOI: 10.1523/ENEURO.0091-18.2018
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Significance Statement
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments
    • Footnotes
    • References
    • Synthesis
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • CGG repeats
  • cognitive impairment
  • epileptiform activity
  • regulatory RNAs
  • RNA localization

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

New Research

  • A Very Fast Time Scale of Human Motor Adaptation: Within Movement Adjustments of Internal Representations during Reaching
  • TrkB Signaling Influences Gene Expression in Cortistatin-Expressing Interneurons
  • Optogenetic Activation of β-Endorphin Terminals in the Medial Preoptic Nucleus Regulates Female Sexual Receptivity
Show more New Research

Disorders of the Nervous System

  • Numbers of granule cells and GABAergic boutons are correlated in shrunken sclerotic hippocampi of sea lions with temporal lobe epilepsy
  • Investigating the Role of Cortical Microglia in a Mouse Model of Viral Infection-Induced Seizures
  • Functional-Structural Coupling: Brain Reorganization in Presbycusis Is Related to Cognitive Impairment
Show more Disorders of the Nervous System

Subjects

  • Disorders of the Nervous System
  • Home
  • Alerts
  • Follow SFN on BlueSky
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Latest Articles
  • Issue Archive
  • Blog
  • Browse by Topic

Information

  • For Authors
  • For the Media

About

  • About the Journal
  • Editorial Board
  • Privacy Notice
  • Contact
  • Feedback
(eNeuro logo)
(SfN logo)

Copyright © 2026 by the Society for Neuroscience.
eNeuro eISSN: 2373-2822

The ideas and opinions expressed in eNeuro do not necessarily reflect those of SfN or the eNeuro Editorial Board. Publication of an advertisement or other product mention in eNeuro should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in eNeuro.