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Research ArticleNew Research, Disorders of the Nervous System

Dopamine Development in the Mouse Orbital Prefrontal Cortex Is Protracted and Sensitive to Amphetamine in Adolescence

Daniel Hoops, Lauren M. Reynolds, Jose-Maria Restrepo-Lozano and Cecilia Flores
eNeuro 9 January 2018, 5 (1) ENEURO.0372-17.2017; https://doi.org/10.1523/ENEURO.0372-17.2017
Daniel Hoops
1Department of Psychiatry, Douglas Mental Health University Institute, McGill University, Montreal, Quebec H4H 1R3, Canada
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Lauren M. Reynolds
1Department of Psychiatry, Douglas Mental Health University Institute, McGill University, Montreal, Quebec H4H 1R3, Canada
2Integrated Program in Neuroscience, McGill University, Montreal, Quebec H3A 1A1, Canada
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Jose-Maria Restrepo-Lozano
1Department of Psychiatry, Douglas Mental Health University Institute, McGill University, Montreal, Quebec H4H 1R3, Canada
2Integrated Program in Neuroscience, McGill University, Montreal, Quebec H3A 1A1, Canada
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Cecilia Flores
1Department of Psychiatry, Douglas Mental Health University Institute, McGill University, Montreal, Quebec H4H 1R3, Canada
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0372-17.2017
PubMed 
29333488
Published By 
Society for Neuroscience
History 
  • Received October 31, 2017
  • Revision received December 14, 2017
  • Accepted December 15, 2017
  • Published online January 9, 2018.
Copyright & Usage 
Copyright © 2018 Hoops et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Daniel Hoops1,
  2. Lauren M. Reynolds1,2,
  3. Jose-Maria Restrepo-Lozano1,2 and
  4. Cecilia Flores1
  1. 1Department of Psychiatry, Douglas Mental Health University Institute, McGill University, Montreal, Quebec H4H 1R3, Canada
  2. 2Integrated Program in Neuroscience, McGill University, Montreal, Quebec H3A 1A1, Canada
  1. Correspondence should be addressed to Dr. Cecilia Flores, Douglas Mental Health University Institute, Perry Pavilion, Room #2111, 6875 LaSalle Boulevard, Montréal (Verdun), Quebec H4H 1R3, Canada, E-mail: cecilia.flores{at}mcgill.ca.
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Author contributions

  1. Author contributions: D.H. and C.F. designed research; D.H., L.M.R., and J.-M.R.-L. performed research; D.H. and C.F. analyzed data; D.H. and C.F. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by National Institute on Drug Abuse Grants R01DA037911 (to C.F.) and F31DA041188 (to L.M.R.), the Natural Science and Engineering Research Council of Canada Grant 2982226 (to C.F.), the Canadian Institutes of Health Research Grant MOP-74709 (to C.F.), and the Quebec Nature and Technology Research Fund Grant 208332 (to D.H.). C.F. is a research scholar of the Fonds de Recherche du Québec-Santé.

Funding

  • HHS | NIH | National Institute on Drug Abuse (NIDA)

    R01DA037911; F31DA041188
  • National Science and Engineering Research Council of Canada (NSERC)

    2982226
  • Gouvernement du Canada | Canadian Institutes of Health Research (CIHR)

    MOP-74709
  • Quebec Nature and Technology Research Fund (FRQNT)

    208332

Other Version

  • You are viewing the most recent version of this article.
  • previous version (January 09, 2018).

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Jan 20181194438173
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Apr 20185713979
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Jul 20251213236
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Total 20251281368298
Jan 20263023233
Feb 20261337945
Mar 202642010
Total 20264763188
Total214799592046
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Dopamine Development in the Mouse Orbital Prefrontal Cortex Is Protracted and Sensitive to Amphetamine in Adolescence
Daniel Hoops, Lauren M. Reynolds, Jose-Maria Restrepo-Lozano, Cecilia Flores
eNeuro 9 January 2018, 5 (1) ENEURO.0372-17.2017; DOI: 10.1523/ENEURO.0372-17.2017

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Dopamine Development in the Mouse Orbital Prefrontal Cortex Is Protracted and Sensitive to Amphetamine in Adolescence
Daniel Hoops, Lauren M. Reynolds, Jose-Maria Restrepo-Lozano, Cecilia Flores
eNeuro 9 January 2018, 5 (1) ENEURO.0372-17.2017; DOI: 10.1523/ENEURO.0372-17.2017
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Keywords

  • drug use
  • guidance cue
  • orbitofrontal cortex
  • piriform cortex

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