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History
- Received August 16, 2017
- Revision received November 28, 2017
- Accepted December 7, 2017
- Published online January 22, 2018.
Copyright & Usage
Copyright © 2018 Kaya et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
Author Information
- Cihan Kaya1,
- Mary H. Cheng1,
- Ethan R. Block3,
- Tom M. Bartol4,
- Terrence J. Sejnowski4,
- Alexander Sorkin2,
- James R. Faeder1 and
- Ivet Bahar1
- 1Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261
- 2Department of Cell Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261
- 3Department of Science, Chatham University, Pittsburgh, PA 15232
- 4Computational Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037
- Correspondence should be addressed to either Ivet Bahar, Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, 3064 Biomedical Science Tower, 3501 Fifth Ave., Pittsburgh, PA, 12261. E-mail: bahar{at}pitt.edu; or James R. Faeder, Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, 3064 Biomedical Science Tower 3501 Fifth Ave., Pittsburgh, PA, 12261. E-mail: faeder{at}pitt.edu.
Author contributions
Author Contributions: CK, JRF, and IB designed the research; CK and MHC performed the computations; CK, JRF, and IB analyzed experimental data provided by ERB and AS. TMB and TJS contributed to analytical tools; CK, JRF, and IB wrote the manuscript; and MHC, ERB, TMB, TJS, and AS contributed to finalizing the manuscript.
Disclosures
The authors declare no competing financial interests.
This work was supported by the National Institutes of Health awards P41GM103712 and P30DA035778 (IB) and R01DA014204 (AS) and National Science Foundation award number ACI-1548562 (Pittsburgh Supercomputing Center).
Funding
HHS | NIH | National Institute of General Medical Sciences (NIGMS)
P41GM103712HHS | NIH | National Institute on Drug Abuse (NIDA)
P30DA035778; R01DA014204
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