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Research ArticleNew Research, Disorders of the Nervous System

Dopamine D2 Receptors in Dopaminergic Neurons Modulate Performance in a Reversal Learning Task in Mice

Jérôme Linden, Alexander S. James, Colin McDaniel and J. David Jentsch
eNeuro 28 February 2018, 5 (1) ENEURO.0229-17.2018; DOI: https://doi.org/10.1523/ENEURO.0229-17.2018
Jérôme Linden
1State University of New York at Binghamton, Binghamton, NY 13902
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Alexander S. James
1State University of New York at Binghamton, Binghamton, NY 13902
2University of California Los Angeles, Los Angeles, CA 90095
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Colin McDaniel
2University of California Los Angeles, Los Angeles, CA 90095
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J. David Jentsch
1State University of New York at Binghamton, Binghamton, NY 13902
2University of California Los Angeles, Los Angeles, CA 90095
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0229-17.2018
PubMed 
29527566
Published By 
Society for Neuroscience
History 
  • Received June 30, 2017
  • Revision received February 5, 2018
  • Accepted February 19, 2018
  • Published online February 28, 2018.
Copyright & Usage 
Copyright © 2018 Linden et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Jérôme Linden1,
  2. Alexander S. James1,2,
  3. Colin McDaniel2 and
  4. J. David Jentsch1,2
  1. 1State University of New York at Binghamton, Binghamton, NY 13902
  2. 2University of California Los Angeles, Los Angeles, CA 90095
  1. Correspondence should be addressed to J. David Jentsch, State University of New York at Binghamton, 4400 Vestal Parkway East (Science 4), Binghamton, NY 13902, E-mail: jjentsch{at}binghamton.edu.
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Author contributions

  1. Author contributions: J.D.J. and A.S.J. designed research; A.S.J., C.M., and J.L. performed research; A.S.J. and J.L. analyzed data; J.L. and J.D.J. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the National Institutes of Health Grant R21-DA038377 (to J.D.J.).

Funding

  • NIH

    R21-DA038377

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Dopamine D2 Receptors in Dopaminergic Neurons Modulate Performance in a Reversal Learning Task in Mice
Jérôme Linden, Alexander S. James, Colin McDaniel, J. David Jentsch
eNeuro 28 February 2018, 5 (1) ENEURO.0229-17.2018; DOI: 10.1523/ENEURO.0229-17.2018

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Dopamine D2 Receptors in Dopaminergic Neurons Modulate Performance in a Reversal Learning Task in Mice
Jérôme Linden, Alexander S. James, Colin McDaniel, J. David Jentsch
eNeuro 28 February 2018, 5 (1) ENEURO.0229-17.2018; DOI: 10.1523/ENEURO.0229-17.2018
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Keywords

  • behavioral flexibility
  • D2
  • Dopamine
  • impulsivity
  • Learning

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