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Research ArticleNew Research, Disorders of the Nervous System

In Vivo Observation of Structural Changes in Neocortical Catecholaminergic Projections in Response to Drugs of Abuse

Mai M. Morimoto, Shinji Tanaka, Shunsuke Mizutani, Shinji Urata, Kazuto Kobayashi and Shigeo Okabe
eNeuro 22 January 2018, 5 (1) ENEURO.0071-17.2018; https://doi.org/10.1523/ENEURO.0071-17.2018
Mai M. Morimoto
1Department of Cellular Neurobiology Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo, 113-0033 Japan
2Department of Experimental Psychology, University College London, 26 Bedford Way, WC1H 0AP, London, UK
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Shinji Tanaka
1Department of Cellular Neurobiology Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo, 113-0033 Japan
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Shunsuke Mizutani
1Department of Cellular Neurobiology Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo, 113-0033 Japan
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Shinji Urata
1Department of Cellular Neurobiology Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo, 113-0033 Japan
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Kazuto Kobayashi
3Department of Molecular Genetics, Institute of Biomedical Sciences, Fukushima Medical University School of Medicine, 960-1295 Japan
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Shigeo Okabe
1Department of Cellular Neurobiology Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo, 113-0033 Japan
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0071-17.2018
PubMed 
29445765
Published By 
Society for Neuroscience
History 
  • Received March 2, 2017
  • Revision received December 30, 2017
  • Accepted January 4, 2018
  • Published online January 22, 2018.
Copyright & Usage 
Copyright © 2018 Morimoto et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Mai M. Morimoto1,2,‡,
  2. Shinji Tanaka1,
  3. Shunsuke Mizutani1,
  4. Shinji Urata1,
  5. Kazuto Kobayashi3 and
  6. Shigeo Okabe1
  1. 1Department of Cellular Neurobiology Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo, 113-0033 Japan
  2. 2Department of Experimental Psychology, University College London, 26 Bedford Way, WC1H 0AP, London, UK
  3. 3Department of Molecular Genetics, Institute of Biomedical Sciences, Fukushima Medical University School of Medicine, 960-1295 Japan
  1. Correspondence should be addressed to Shigeo Okabe at the above address, E-mail: okabe{at}m.u-tokyo.ac.jp.
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Author contributions

  1. Author contribution: M.M.M., K.K., and S.O. designed research; M.M.M., S.T., S.M., and S.U. performed research; M.M.M. analyzed data; M.M.M. and S.O. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by Grants-in-Aid for Scientific Research 17H01387, 26250014, and 25117006 (to S.O.) and the Core Research for Evolutional Science and Technology from the Japan Science and Technology Agency Grant JPMJCR14W2 (to S.O.), Uehara Memorial Foundation (S.O.), and University of Tokyo Center for Integrative Science of Human Behavior.

  • ↵‡ Current address: Department of Experimental Psychology, University College London, 26 Bedford Way, WC1H 0AP, London, UK.

Funding

  • Japan Society for the Promotion of Science (JSPS)

    17H01387; 26250014; 25117006
  • Japan Science and Technology Agency (JST)

    JPMJCR14W2
  • Uehara Memorial Foundation

  • UTokyo Center for Integrative Science of Human Behavior (CiSHuB)

Other Version

  • You are viewing the most recent version of this article.
  • previous version (January 22, 2018).

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Jan 2018186034
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May 202503911
Jun 202565310
Jul 2025051
Total 20251727661
Total97640091023
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In Vivo Observation of Structural Changes in Neocortical Catecholaminergic Projections in Response to Drugs of Abuse
Mai M. Morimoto, Shinji Tanaka, Shunsuke Mizutani, Shinji Urata, Kazuto Kobayashi, Shigeo Okabe
eNeuro 22 January 2018, 5 (1) ENEURO.0071-17.2018; DOI: 10.1523/ENEURO.0071-17.2018

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In Vivo Observation of Structural Changes in Neocortical Catecholaminergic Projections in Response to Drugs of Abuse
Mai M. Morimoto, Shinji Tanaka, Shunsuke Mizutani, Shinji Urata, Kazuto Kobayashi, Shigeo Okabe
eNeuro 22 January 2018, 5 (1) ENEURO.0071-17.2018; DOI: 10.1523/ENEURO.0071-17.2018
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Keywords

  • axon
  • catecholamine
  • in vivo Imaging
  • methamphetamine
  • neocortex
  • transgenic mouse

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