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Research ArticleNew Research, Neuronal Excitability

Altered Chloride Homeostasis Decreases the Action Potential Threshold and Increases Hyperexcitability in Hippocampal Neurons

Andreas T. Sørensen, Marco Ledri, Miriam Melis, Litsa Nikitidou Ledri, My Andersson and Merab Kokaia
eNeuro 7 December 2017, 4 (6) ENEURO.0172-17.2017; DOI: https://doi.org/10.1523/ENEURO.0172-17.2017
Andreas T. Sørensen
Experimental Epilepsy Group, Epilepsy Center, Department of Clinical Sciences, Lund University Hospital, Lund 22184, Sweden
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Marco Ledri
Experimental Epilepsy Group, Epilepsy Center, Department of Clinical Sciences, Lund University Hospital, Lund 22184, Sweden
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Miriam Melis
Experimental Epilepsy Group, Epilepsy Center, Department of Clinical Sciences, Lund University Hospital, Lund 22184, Sweden
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Litsa Nikitidou Ledri
Experimental Epilepsy Group, Epilepsy Center, Department of Clinical Sciences, Lund University Hospital, Lund 22184, Sweden
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My Andersson
Experimental Epilepsy Group, Epilepsy Center, Department of Clinical Sciences, Lund University Hospital, Lund 22184, Sweden
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Merab Kokaia
Experimental Epilepsy Group, Epilepsy Center, Department of Clinical Sciences, Lund University Hospital, Lund 22184, Sweden
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eneuro: 4 (6)
eNeuro
Vol. 4, Issue 6
November/December 2017
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Altered Chloride Homeostasis Decreases the Action Potential Threshold and Increases Hyperexcitability in Hippocampal Neurons
Andreas T. Sørensen, Marco Ledri, Miriam Melis, Litsa Nikitidou Ledri, My Andersson, Merab Kokaia
eNeuro 7 December 2017, 4 (6) ENEURO.0172-17.2017; DOI: 10.1523/ENEURO.0172-17.2017

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Altered Chloride Homeostasis Decreases the Action Potential Threshold and Increases Hyperexcitability in Hippocampal Neurons
Andreas T. Sørensen, Marco Ledri, Miriam Melis, Litsa Nikitidou Ledri, My Andersson, Merab Kokaia
eNeuro 7 December 2017, 4 (6) ENEURO.0172-17.2017; DOI: 10.1523/ENEURO.0172-17.2017
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Keywords

  • action potential threshold
  • chloride
  • eNpHR3.0
  • GABAA receptors
  • halorhodopsin
  • optogenetics

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