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Research ArticleMethods/New Tools, Novel Tools and Methods

Quantifying Mesoscale Neuroanatomy Using X-Ray Microtomography

Eva L. Dyer, William Gray Roncal, Judy A. Prasad, Hugo L. Fernandes, Doga Gürsoy, Vincent De Andrade, Kamel Fezzaa, Xianghui Xiao, Joshua T. Vogelstein, Chris Jacobsen, Konrad P. Körding and Narayanan Kasthuri
eNeuro 25 September 2017, 4 (5) ENEURO.0195-17.2017; DOI: https://doi.org/10.1523/ENEURO.0195-17.2017
Eva L. Dyer
1Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, 30332
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William Gray Roncal
2The Johns Hopkins University Applied Physics Laboratory, Laurel, MD, 20723
3Dept. of Computer Science, The Johns Hopkins University, Baltimore, MD, 21218
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Judy A. Prasad
4Dept. of Neurobiology, University of Chicago, Chicago, IL, 60637
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Hugo L. Fernandes
5Dept. of Physical Medicine and Rehabilitation, Northwestern University, Chicago, IL, 60611
6Sensory Motor Performance Program, Rehabilitation Institute of Chicago, Chicago, IL, 60611
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Doga Gürsoy
7Advanced Photon Source, Argonne National Laboratory, Lemont, IL, 60439
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Vincent De Andrade
7Advanced Photon Source, Argonne National Laboratory, Lemont, IL, 60439
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Kamel Fezzaa
7Advanced Photon Source, Argonne National Laboratory, Lemont, IL, 60439
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Xianghui Xiao
7Advanced Photon Source, Argonne National Laboratory, Lemont, IL, 60439
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Joshua T. Vogelstein
8Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, MD, 21205
9Institute of Computational Medicine, The Johns Hopkins University, Baltimore, MD, 21218
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Chris Jacobsen
7Advanced Photon Source, Argonne National Laboratory, Lemont, IL, 60439
10Department of Physics and Astronomy, Northwestern University, Chicago, IL, 60208
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Konrad P. Körding
11Department of Biomedical Engineering, University of Pennsylvania, Philadelphia, PA, 19104
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Narayanan Kasthuri
4Dept. of Neurobiology, University of Chicago, Chicago, IL, 60637
12Center for Nanoscale Materials, Argonne National Laboratory, Lemont, IL, 60439
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eneuro: 4 (5)
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September/October 2017
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Quantifying Mesoscale Neuroanatomy Using X-Ray Microtomography
Eva L. Dyer, William Gray Roncal, Judy A. Prasad, Hugo L. Fernandes, Doga Gürsoy, Vincent De Andrade, Kamel Fezzaa, Xianghui Xiao, Joshua T. Vogelstein, Chris Jacobsen, Konrad P. Körding, Narayanan Kasthuri
eNeuro 25 September 2017, 4 (5) ENEURO.0195-17.2017; DOI: 10.1523/ENEURO.0195-17.2017

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Quantifying Mesoscale Neuroanatomy Using X-Ray Microtomography
Eva L. Dyer, William Gray Roncal, Judy A. Prasad, Hugo L. Fernandes, Doga Gürsoy, Vincent De Andrade, Kamel Fezzaa, Xianghui Xiao, Joshua T. Vogelstein, Chris Jacobsen, Konrad P. Körding, Narayanan Kasthuri
eNeuro 25 September 2017, 4 (5) ENEURO.0195-17.2017; DOI: 10.1523/ENEURO.0195-17.2017
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Keywords

  • Automated Segmentation
  • cell counting
  • electron microscopy
  • neocortex
  • neuroanatomy
  • X-Ray Microtomography

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Methods/New Tools

  • A Toolbox of Criteria for Distinguishing Cajal–Retzius Cells from Other Neuronal Types in the Postnatal Mouse Hippocampus
  • Superficial Bound of the Depth Limit of Two-Photon Imaging in Mouse Brain
  • Assessment of Spontaneous Neuronal Activity In Vitro Using Multi-Well Multi-Electrode Arrays: Implications for Assay Development
Show more Methods/New Tools

Novel Tools and Methods

  • A Toolbox of Criteria for Distinguishing Cajal–Retzius Cells from Other Neuronal Types in the Postnatal Mouse Hippocampus
  • Superficial Bound of the Depth Limit of Two-Photon Imaging in Mouse Brain
  • Assessment of Spontaneous Neuronal Activity In Vitro Using Multi-Well Multi-Electrode Arrays: Implications for Assay Development
Show more Novel Tools and Methods

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