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Research ArticleNew Research, Neuronal Excitability

Acute Effect of Pore-Forming Clostridium perfringens ε-Toxin on Compound Action Potentials of Optic Nerve of Mouse

Mercè Cases, Artur Llobet, Beatrice Terni, Inmaculada Gómez de Aranda, Marta Blanch, Briain Doohan, Alexander Revill, Angus M. Brown, Juan Blasi and Carles Solsona
eNeuro 31 July 2017, 4 (4) ENEURO.0051-17.2017; https://doi.org/10.1523/ENEURO.0051-17.2017
Mercè Cases
1Laboratory of Cellular and Molecular Neurobiology, Department of Pathology and Experimental Therapeutics, Faculty of Medicine and Health Sciences, Campus of Bellvitge, University of Barcelona, Hospitalet de Llobregat, Barcelona 08907, Spain
2Institut d’Investigació Biomèdica de Bellvitge - Biomedical Research Institute of Bellvitge (IDIBELL), Hospitalet de Llobregat, Barcelona 08907, Spain
3Institute of Neurosciences, University of Barcelona, Barcelona 08035, Spain
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Artur Llobet
1Laboratory of Cellular and Molecular Neurobiology, Department of Pathology and Experimental Therapeutics, Faculty of Medicine and Health Sciences, Campus of Bellvitge, University of Barcelona, Hospitalet de Llobregat, Barcelona 08907, Spain
2Institut d’Investigació Biomèdica de Bellvitge - Biomedical Research Institute of Bellvitge (IDIBELL), Hospitalet de Llobregat, Barcelona 08907, Spain
3Institute of Neurosciences, University of Barcelona, Barcelona 08035, Spain
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Beatrice Terni
2Institut d’Investigació Biomèdica de Bellvitge - Biomedical Research Institute of Bellvitge (IDIBELL), Hospitalet de Llobregat, Barcelona 08907, Spain
3Institute of Neurosciences, University of Barcelona, Barcelona 08035, Spain
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Inmaculada Gómez de Aranda
1Laboratory of Cellular and Molecular Neurobiology, Department of Pathology and Experimental Therapeutics, Faculty of Medicine and Health Sciences, Campus of Bellvitge, University of Barcelona, Hospitalet de Llobregat, Barcelona 08907, Spain
3Institute of Neurosciences, University of Barcelona, Barcelona 08035, Spain
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Marta Blanch
1Laboratory of Cellular and Molecular Neurobiology, Department of Pathology and Experimental Therapeutics, Faculty of Medicine and Health Sciences, Campus of Bellvitge, University of Barcelona, Hospitalet de Llobregat, Barcelona 08907, Spain
2Institut d’Investigació Biomèdica de Bellvitge - Biomedical Research Institute of Bellvitge (IDIBELL), Hospitalet de Llobregat, Barcelona 08907, Spain
3Institute of Neurosciences, University of Barcelona, Barcelona 08035, Spain
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Briain Doohan
4School of Biomedical Sciences, Queen’s Medical Centre, University of Nottingham, Nottingham NG7 2UH, United Kingdom
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Alexander Revill
4School of Biomedical Sciences, Queen’s Medical Centre, University of Nottingham, Nottingham NG7 2UH, United Kingdom
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Angus M. Brown
4School of Biomedical Sciences, Queen’s Medical Centre, University of Nottingham, Nottingham NG7 2UH, United Kingdom
5Department of Neurology, University of Washington, Seattle, WA 98195
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Juan Blasi
1Laboratory of Cellular and Molecular Neurobiology, Department of Pathology and Experimental Therapeutics, Faculty of Medicine and Health Sciences, Campus of Bellvitge, University of Barcelona, Hospitalet de Llobregat, Barcelona 08907, Spain
2Institut d’Investigació Biomèdica de Bellvitge - Biomedical Research Institute of Bellvitge (IDIBELL), Hospitalet de Llobregat, Barcelona 08907, Spain
3Institute of Neurosciences, University of Barcelona, Barcelona 08035, Spain
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Carles Solsona
1Laboratory of Cellular and Molecular Neurobiology, Department of Pathology and Experimental Therapeutics, Faculty of Medicine and Health Sciences, Campus of Bellvitge, University of Barcelona, Hospitalet de Llobregat, Barcelona 08907, Spain
2Institut d’Investigació Biomèdica de Bellvitge - Biomedical Research Institute of Bellvitge (IDIBELL), Hospitalet de Llobregat, Barcelona 08907, Spain
3Institute of Neurosciences, University of Barcelona, Barcelona 08035, Spain
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Acute Effect of Pore-Forming Clostridium perfringens ε-Toxin on Compound Action Potentials of Optic Nerve of Mouse
Mercè Cases, Artur Llobet, Beatrice Terni, Inmaculada Gómez de Aranda, Marta Blanch, Briain Doohan, Alexander Revill, Angus M. Brown, Juan Blasi, Carles Solsona
eNeuro 31 July 2017, 4 (4) ENEURO.0051-17.2017; DOI: 10.1523/ENEURO.0051-17.2017

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Acute Effect of Pore-Forming Clostridium perfringens ε-Toxin on Compound Action Potentials of Optic Nerve of Mouse
Mercè Cases, Artur Llobet, Beatrice Terni, Inmaculada Gómez de Aranda, Marta Blanch, Briain Doohan, Alexander Revill, Angus M. Brown, Juan Blasi, Carles Solsona
eNeuro 31 July 2017, 4 (4) ENEURO.0051-17.2017; DOI: 10.1523/ENEURO.0051-17.2017
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Keywords

  • action potential
  • atp release
  • clostridial toxin
  • electrophysiology
  • myelin
  • optic nerve

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