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Research ArticleNew Research, Neuronal Excitability

Shaping of Signal Transmission at the Photoreceptor Synapse by EAAT2 Glutamate Transporters

Stephanie Niklaus, Lucia Cadetti, Colette M. vom Berg-Maurer, André Lehnherr, Adriana L. Hotz, Ian C. Forster, Matthias Gesemann and Stephan C.F. Neuhauss
eNeuro 5 June 2017, 4 (3) ENEURO.0339-16.2017; https://doi.org/10.1523/ENEURO.0339-16.2017
Stephanie Niklaus
1Institute of Molecular Life Sciences, University of Zurich, Zurich, CH-8057, Switzerland
3Life Science Zürich Graduate Program – Neuroscience, Zurich, CH-8057, Switzerland
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Lucia Cadetti
1Institute of Molecular Life Sciences, University of Zurich, Zurich, CH-8057, Switzerland
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Colette M. vom Berg-Maurer
1Institute of Molecular Life Sciences, University of Zurich, Zurich, CH-8057, Switzerland
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  • ORCID record for Colette M. vom Berg-Maurer
André Lehnherr
1Institute of Molecular Life Sciences, University of Zurich, Zurich, CH-8057, Switzerland
3Life Science Zürich Graduate Program – Neuroscience, Zurich, CH-8057, Switzerland
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Adriana L. Hotz
1Institute of Molecular Life Sciences, University of Zurich, Zurich, CH-8057, Switzerland
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Ian C. Forster
2Institute of Physiology, Zurich, CH-8057, Switzerland
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Matthias Gesemann
1Institute of Molecular Life Sciences, University of Zurich, Zurich, CH-8057, Switzerland
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Stephan C.F. Neuhauss
1Institute of Molecular Life Sciences, University of Zurich, Zurich, CH-8057, Switzerland
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0339-16.2017
PubMed 
28612046
Published By 
Society for Neuroscience
History 
  • Received November 10, 2016
  • Revision received May 12, 2017
  • Accepted May 25, 2017
  • Published online June 5, 2017.
Copyright & Usage 
Copyright © 2017 Niklaus et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Stephanie Niklaus1,3,*,
  2. Lucia Cadetti1,*,
  3. Colette M. vom Berg-Maurer1,
  4. André Lehnherr1,3,
  5. Adriana L. Hotz1,
  6. Ian C. Forster2,
  7. Matthias Gesemann1 and
  8. Stephan C.F. Neuhauss1
  1. 1Institute of Molecular Life Sciences, University of Zurich, Zurich, CH-8057, Switzerland
  2. 2Institute of Physiology, Zurich, CH-8057, Switzerland
  3. 3Life Science Zürich Graduate Program – Neuroscience, Zurich, CH-8057, Switzerland
  1. Correspondence should be addressed to Stephan C.F. Neuhauss, Institute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland. E-mail: stephan.neuhauss{at}imls.uzh.ch.
  • Colette M. vom Berg-Maurer’s present address: Eawag, Swiss Federal Institute of Aquatic Science and Technology, 8600, Dübendorf, Switzerland.

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Author contributions

  1. ↵* S.N. and L.C. contributed equally to this work.

  • Colette M. vom Berg-Maurer’s present address: Eawag, Swiss Federal Institute of Aquatic Science and Technology, 8600, Dübendorf, Switzerland.

Disclosures

  • Authors report no conflict of interest.

  • Authors’ Contributions: SN performed histology and electroretinography, prepared Figs. 1–4, and wrote the manuscript; LC made oocyte recordings, prepared Fig. 5, and contributed to manuscript writing; CMvBM cloned the genes, did initial physiological and histological analyses, and wrote an earlier version of the manuscript; AL and ALH contributed to expression analyses; ICF contributed to oocyte recordings; MG contributed to cloning and phylogenetic analyses; SCFN conceived and coordinated the study and contributed to manuscript writing; and all authors edited and approved the manuscript.

  • Funding: This work was supported by the Swiss National Science Foundation (31003A_153289/1).

Funding

  • Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (SNF)

    501100001711; 31003A_153289/1

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Total709107701546
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Shaping of Signal Transmission at the Photoreceptor Synapse by EAAT2 Glutamate Transporters
Stephanie Niklaus, Lucia Cadetti, Colette M. vom Berg-Maurer, André Lehnherr, Adriana L. Hotz, Ian C. Forster, Matthias Gesemann, Stephan C.F. Neuhauss
eNeuro 5 June 2017, 4 (3) ENEURO.0339-16.2017; DOI: 10.1523/ENEURO.0339-16.2017

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Shaping of Signal Transmission at the Photoreceptor Synapse by EAAT2 Glutamate Transporters
Stephanie Niklaus, Lucia Cadetti, Colette M. vom Berg-Maurer, André Lehnherr, Adriana L. Hotz, Ian C. Forster, Matthias Gesemann, Stephan C.F. Neuhauss
eNeuro 5 June 2017, 4 (3) ENEURO.0339-16.2017; DOI: 10.1523/ENEURO.0339-16.2017
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Keywords

  • Excitatory Amino Acid Transporter
  • glutamate
  • retina
  • zebrafish

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