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Research ArticleNegative Results, Integrative Systems

Effects of Selective Deletion of Tyrosine Hydroxylase from Kisspeptin Cells on Puberty and Reproduction in Male and Female Mice

Shannon B. Z. Stephens, Melvin L. Rouse, Kristen P. Tolson, Reanna B. Liaw, Ruby A. Parra, Navi Chahal and Alexander S. Kauffman
eNeuro 15 June 2017, 4 (3) ENEURO.0150-17.2017; https://doi.org/10.1523/ENEURO.0150-17.2017
Shannon B. Z. Stephens
Department of Reproductive Medicine, University of California, San Diego La Jolla, CA 92093
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Melvin L. Rouse
Department of Reproductive Medicine, University of California, San Diego La Jolla, CA 92093
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  • ORCID record for Melvin L. Rouse
Kristen P. Tolson
Department of Reproductive Medicine, University of California, San Diego La Jolla, CA 92093
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Reanna B. Liaw
Department of Reproductive Medicine, University of California, San Diego La Jolla, CA 92093
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Ruby A. Parra
Department of Reproductive Medicine, University of California, San Diego La Jolla, CA 92093
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Navi Chahal
Department of Reproductive Medicine, University of California, San Diego La Jolla, CA 92093
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Alexander S. Kauffman
Department of Reproductive Medicine, University of California, San Diego La Jolla, CA 92093
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0150-17.2017
PubMed 
28660243
Published By 
Society for Neuroscience
History 
  • Received May 3, 2017
  • Revision received June 8, 2017
  • Accepted June 9, 2017
  • Published online June 15, 2017.
Copyright & Usage 
Copyright © 2017 Stephens et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Shannon B. Z. Stephens,
  2. Melvin L. Rouse,
  3. Kristen P. Tolson,
  4. Reanna B. Liaw,
  5. Ruby A. Parra,
  6. Navi Chahal and
  7. Alexander S. Kauffman
  1. Department of Reproductive Medicine, University of California, San Diego La Jolla, CA 92093
  1. Correspondence should be addressed to Alexander S. Kauffman, Department of Reproductive Medicine, Leichtag Building, Room 3A-15, University of California, San Diego, 9500 Gilman Drive, #0674, La Jolla, CA 92093, E-mail: akauffman{at}ucsd.edu.
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Author contributions

  1. Author contributions: S.B.Z.S., M.L.R., K.P.T., and A.S.K. designed research; S.B.Z.S., M.L.R., K.P.T., R.B.L., R.A.P., N.C., and A.S.K. performed research; S.B.Z.S., M.L.R., R.B.L., and A.S.K. analyzed data; S.B.Z.S. and A.S.K. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by NSF Grant IOS-1457226 and NIH Grant R01 HD082567, P50 HD012303 (University of California, San Diego), and P50 HD28934 (University of Virginia). S.B.Z.S. was supported by NIH Grants F32 HD088060 and T32 HD007203.

Funding

  • HHS | NIH | NICHD | National Center for Medical Rehabilitation Research (NCMRR)

    100006937; P50 HD012303
  • HHS | NIH | NICHD | National Center for Medical Rehabilitation Research (NCMRR)

    100006937; R01 HD082567
  • HHS | NIH | NICHD | National Center for Medical Rehabilitation Research (NCMRR)

    100006937; P50 HD28934
  • HHS | NIH | NICHD | National Center for Medical Rehabilitation Research (NCMRR)

    100006937; F32 HD088060
  • HHS | NIH | NICHD | National Center for Medical Rehabilitation Research (NCMRR)

    100006937; T32 HD007203
  • NSF | BIO | Division of Integrative Organismal Systems (IOS)

    100000154; IOS-1457226

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Jul 2017427280
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Sep 2017407353
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Apr 2018124125
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Apr 20219587
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Jul 2025710832
Aug 2025125627
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Total 202567768188
Total73455331703
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Effects of Selective Deletion of Tyrosine Hydroxylase from Kisspeptin Cells on Puberty and Reproduction in Male and Female Mice
Shannon B. Z. Stephens, Melvin L. Rouse, Kristen P. Tolson, Reanna B. Liaw, Ruby A. Parra, Navi Chahal, Alexander S. Kauffman
eNeuro 15 June 2017, 4 (3) ENEURO.0150-17.2017; DOI: 10.1523/ENEURO.0150-17.2017

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Effects of Selective Deletion of Tyrosine Hydroxylase from Kisspeptin Cells on Puberty and Reproduction in Male and Female Mice
Shannon B. Z. Stephens, Melvin L. Rouse, Kristen P. Tolson, Reanna B. Liaw, Ruby A. Parra, Navi Chahal, Alexander S. Kauffman
eNeuro 15 June 2017, 4 (3) ENEURO.0150-17.2017; DOI: 10.1523/ENEURO.0150-17.2017
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Keywords

  • dopamine
  • GnRH
  • Kiss1
  • kisspeptin
  • puberty
  • reproduction

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