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Research ArticleNew Research, Disorders of the Nervous System

Obesity Accelerates Alzheimer-Related Pathology in APOE4 but not APOE3 Mice

V. Alexandra Moser and Christian J. Pike
eNeuro 12 June 2017, 4 (3) ENEURO.0077-17.2017; https://doi.org/10.1523/ENEURO.0077-17.2017
V. Alexandra Moser
Neuroscience Graduate Program, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089
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Christian J. Pike
Neuroscience Graduate Program, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0077-17.2017
PubMed 
28612048
Published By 
Society for Neuroscience
History 
  • Received March 7, 2017
  • Revision received May 17, 2017
  • Accepted May 22, 2017
  • Published online June 12, 2017.
Copyright & Usage 
Copyright © 2017 Moser and Pike This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. V. Alexandra Moser and
  2. Christian J. Pike
  1. Neuroscience Graduate Program, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089
  1. Correspondence should be addressed to Christian J. Pike, Ph.D., Leonard Davis School of Gerontology, University of Southern California, 3715 McClintock Avenue, Los Angeles, CA 90089-0191, E-mail: cjpike{at}usc.edu.
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Author contributions

  1. Author contributions: V.A.M. and C.J.P. designed research; V.A.M. performed research; V.A.M. analyzed data; V.A.M. and C.J.P. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This study was supported by NIH Grants AG034103 (to C.J.P.) and AG051521 (to C.J.P.).

Funding

  • HHS | NIH | National Institute on Aging (NIA)

    100000049; AG034103
  • HHS | NIH | National Institute on Aging (NIA)

    100000049; AG051521

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  • You are viewing the most recent version of this article.
  • previous version (June 12, 2017).

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Jun 2017257067
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Sep 201797188103
Oct 201795157104
Nov 201784171117
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Feb 2018534917
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Apr 20185912195
May 20184711933
Jun 20183610869
Jul 20182314239
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Total 20184712004451
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Mar 2019615712
Apr 20191515318
May 2019411610
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Jul 201917119
Aug 2019106111
Oct 201987113
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Total 2019871368167
Jan 202068612
Feb 202067427
Mar 202045714
May 202025118
Jun 202023814
Jul 202054714
Aug 202097617
Sep 202046619
Oct 20206897
Nov 202077124
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Total 202060748183
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Feb 202106210
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Apr 202139331
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Jun 202137212
Jul 202138328
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Total 202239742189
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Total 20241511790294
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Apr 202585826
May 2025722625
Jun 20251513926
Jul 20251517852
Aug 2025108550
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Total 20251331487395
Jan 20261319246
Feb 20261232315
Mar 20261348
Total 20262654969
Total1708151202846
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eneuro: 4 (3)
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May/June 2017
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Obesity Accelerates Alzheimer-Related Pathology in APOE4 but not APOE3 Mice
V. Alexandra Moser, Christian J. Pike
eNeuro 12 June 2017, 4 (3) ENEURO.0077-17.2017; DOI: 10.1523/ENEURO.0077-17.2017

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Obesity Accelerates Alzheimer-Related Pathology in APOE4 but not APOE3 Mice
V. Alexandra Moser, Christian J. Pike
eNeuro 12 June 2017, 4 (3) ENEURO.0077-17.2017; DOI: 10.1523/ENEURO.0077-17.2017
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Keywords

  • Alzheimer’s disease
  • apolipoprotein E
  • β-amyloid
  • gliosis
  • obesity
  • transgenic

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