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Research ArticleNew Research, Cognition and Behavior

Nonstationary Stochastic Dynamics Underlie Spontaneous Transitions between Active and Inactive Behavioral States

Alexandre Melanson, Jorge F. Mejias, James J. Jun, Leonard Maler and André Longtin
eNeuro 21 March 2017, 4 (2) ENEURO.0355-16.2017; https://doi.org/10.1523/ENEURO.0355-16.2017
Alexandre Melanson
1Department of Physics, University of Ottawa, Ottawa, Ontario, Canada, K1N 6N5
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Jorge F. Mejias
1Department of Physics, University of Ottawa, Ottawa, Ontario, Canada, K1N 6N5
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James J. Jun
1Department of Physics, University of Ottawa, Ottawa, Ontario, Canada, K1N 6N5
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Leonard Maler
2Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada, K1H 8M5
3Center for Neural Dynamics, University of Ottawa, Ottawa, Ontario, Canada, K1N 6N5
4Brain and Mind Research Institute, Department of Medecine, University of Ottawa, Ottawa, Ontario, Canada, K1H 8M5
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André Longtin
1Department of Physics, University of Ottawa, Ottawa, Ontario, Canada, K1N 6N5
3Center for Neural Dynamics, University of Ottawa, Ottawa, Ontario, Canada, K1N 6N5
4Brain and Mind Research Institute, Department of Medecine, University of Ottawa, Ottawa, Ontario, Canada, K1H 8M5
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0355-16.2017
PubMed 
28374017
Published By 
Society for Neuroscience
History 
  • Received December 1, 2016
  • Revision received February 16, 2017
  • Accepted February 22, 2017
  • Published online March 21, 2017.
Copyright & Usage 
Copyright © 2017 Melanson et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Alexandre Melanson1,
  2. Jorge F. Mejias1,
  3. James J. Jun1,
  4. Leonard Maler2,3,4 and
  5. André Longtin1,3,4
  1. 1Department of Physics, University of Ottawa, Ottawa, Ontario, Canada, K1N 6N5
  2. 2Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada, K1H 8M5
  3. 3Center for Neural Dynamics, University of Ottawa, Ottawa, Ontario, Canada, K1N 6N5
  4. 4Brain and Mind Research Institute, Department of Medecine, University of Ottawa, Ottawa, Ontario, Canada, K1H 8M5
  1. Correspondence should be addressed to Alexandre Melanson, Department of Physics, University of Ottawa, Ottawa, Ontario, Canada, K1N 6N5, E-mail: melanson.alexandre{at}gmail.com.
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Author contributions

  1. Author contributions: A.M., J.M., L.M., and A.L. designed research; A.M. and J.M. performed research; A.M. and J.J. analyzed data; A.M. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the National Sciences and Engineering Research Council of Canada and the Canadian Institute of Health Research.

Funding

  • National Sciences and Engineering Council of Canada

  • Canadian Institute for Health Research

Other Version

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  • previous version (March 21, 2017).

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Aug 202575829
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Total65076431412
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Nonstationary Stochastic Dynamics Underlie Spontaneous Transitions between Active and Inactive Behavioral States
Alexandre Melanson, Jorge F. Mejias, James J. Jun, Leonard Maler, André Longtin
eNeuro 21 March 2017, 4 (2) ENEURO.0355-16.2017; DOI: 10.1523/ENEURO.0355-16.2017

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Nonstationary Stochastic Dynamics Underlie Spontaneous Transitions between Active and Inactive Behavioral States
Alexandre Melanson, Jorge F. Mejias, James J. Jun, Leonard Maler, André Longtin
eNeuro 21 March 2017, 4 (2) ENEURO.0355-16.2017; DOI: 10.1523/ENEURO.0355-16.2017
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Keywords

  • behavioral state transitions
  • Bistability
  • Computer Simulations
  • Electric Fish
  • Spontaneous Movement
  • Stochastic Differential Equation

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