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Research ArticleNew Research, Sensory and Motor Systems

Afferent Fiber Remodeling in the Somatosensory Thalamus of Mice as a Neural Basis of Somatotopic Reorganization in the Brain and Ectopic Mechanical Hypersensitivity after Peripheral Sensory Nerve Injury

Yuichi Takeuchi, Hironobu Osaki, Yuki Yagasaki, Yoko Katayama and Mariko Miyata
eNeuro 23 March 2017, 4 (2) ENEURO.0345-16.2017; https://doi.org/10.1523/ENEURO.0345-16.2017
Yuichi Takeuchi
1Department of Physiology, School of Medicine, Tokyo Women’s Medical University, Tokyo 162-8666, Japan
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  • ORCID record for Yuichi Takeuchi
Hironobu Osaki
1Department of Physiology, School of Medicine, Tokyo Women’s Medical University, Tokyo 162-8666, Japan
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Yuki Yagasaki
1Department of Physiology, School of Medicine, Tokyo Women’s Medical University, Tokyo 162-8666, Japan
2Division of Women Health Care Professionals and Researchers Support, TWMU Career Development Center for Medical Professionals, Tokyo Women’s Medical University, Tokyo 162-8666, Japan
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Yoko Katayama
1Department of Physiology, School of Medicine, Tokyo Women’s Medical University, Tokyo 162-8666, Japan
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Mariko Miyata
1Department of Physiology, School of Medicine, Tokyo Women’s Medical University, Tokyo 162-8666, Japan
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0345-16.2017
PubMed 
28396882
Published By 
Society for Neuroscience
History 
  • Received November 21, 2016
  • Revision received February 22, 2017
  • Accepted March 3, 2017
  • Published online March 23, 2017.
Copyright & Usage 
Copyright © 2017 Takeuchi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Yuichi Takeuchi1,
  2. Hironobu Osaki1,
  3. Yuki Yagasaki1,2,
  4. Yoko Katayama1 and
  5. Mariko Miyata1
  1. 1Department of Physiology, School of Medicine, Tokyo Women’s Medical University, Tokyo 162-8666, Japan
  2. 2Division of Women Health Care Professionals and Researchers Support, TWMU Career Development Center for Medical Professionals, Tokyo Women’s Medical University, Tokyo 162-8666, Japan
  1. Correspondence should be addressed to Mariko Miyata, M.D., Ph.D., Department of Physiology, School of Medicine, Tokyo Women’s Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan, E-Mail: mmiyata{at}twmu.ac.jp.
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Author contributions

  1. Author contributions: Y.T. and M.M. designed research; Y.T., H.O., Y.Y., and Y.K. performed research; Y.T., H.O., Y.Y., and Y.K. analyzed data; Y.T. and M.M. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This study was supported by Grants-in-Aid for Scientific Research (18500316, 20021029, 22800063, 23500400, 25870757, 26290010, 09J00032, and 15K21387), Grants-in-Aid for Scientific Research on Innovative Areas (15H01667 and 16H01344), The Uehara Memorial Foundation, Aya Irisawa Memorial Promotion Award, SHISEIKAI Scholarship Fund for basic researcher of medical science, Keiko Watanabe Award, and Research grant for Support Center for Women Health Care Professionals and Researchers, Tokyo Women’s Medical University.

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Apr 2017133233
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Jan 2025195431
Feb 2025116913
Mar 202545824
Apr 202536232
May 20258278
Total 202545270108
Total107951001791
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Afferent Fiber Remodeling in the Somatosensory Thalamus of Mice as a Neural Basis of Somatotopic Reorganization in the Brain and Ectopic Mechanical Hypersensitivity after Peripheral Sensory Nerve Injury
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Afferent Fiber Remodeling in the Somatosensory Thalamus of Mice as a Neural Basis of Somatotopic Reorganization in the Brain and Ectopic Mechanical Hypersensitivity after Peripheral Sensory Nerve Injury
Yuichi Takeuchi, Hironobu Osaki, Yuki Yagasaki, Yoko Katayama, Mariko Miyata
eNeuro 23 March 2017, 4 (2) ENEURO.0345-16.2017; DOI: 10.1523/ENEURO.0345-16.2017

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Afferent Fiber Remodeling in the Somatosensory Thalamus of Mice as a Neural Basis of Somatotopic Reorganization in the Brain and Ectopic Mechanical Hypersensitivity after Peripheral Sensory Nerve Injury
Yuichi Takeuchi, Hironobu Osaki, Yuki Yagasaki, Yoko Katayama, Mariko Miyata
eNeuro 23 March 2017, 4 (2) ENEURO.0345-16.2017; DOI: 10.1523/ENEURO.0345-16.2017
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Keywords

  • nerve injury
  • thalamus

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