Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT

User menu

Search

  • Advanced search
eNeuro

eNeuro

Advanced Search

 

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT
PreviousNext
Research ArticleNew Research, Disorders of the Nervous System

Efficient Remyelination Requires DNA Methylation

Sarah Moyon, Dan Ma, Jimmy L. Huynh, David J.C. Coutts, Chao Zhao, Patrizia Casaccia and Robin J.M. Franklin
eNeuro 20 March 2017, 4 (2) ENEURO.0336-16.2017; DOI: https://doi.org/10.1523/ENEURO.0336-16.2017
Sarah Moyon
1Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Sarah Moyon
Dan Ma
4Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute and Department of Clinical Neurosciences, University of Cambridge, Cambridge, CB2 0AH, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Dan Ma
Jimmy L. Huynh
1Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029
2Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
David J.C. Coutts
4Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute and Department of Clinical Neurosciences, University of Cambridge, Cambridge, CB2 0AH, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for David J.C. Coutts
Chao Zhao
4Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute and Department of Clinical Neurosciences, University of Cambridge, Cambridge, CB2 0AH, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Chao Zhao
Patrizia Casaccia
1Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029
2Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029
3Neuroscience Initiative Advanced Science Research Center, CUNY, New York, NY 10031
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Patrizia Casaccia
Robin J.M. Franklin
4Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute and Department of Clinical Neurosciences, University of Cambridge, Cambridge, CB2 0AH, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/ENEURO.0336-16.2017
PubMed 
28451635
Published By 
Society for Neuroscience
History 
  • Received November 7, 2016
  • Revision received January 28, 2017
  • Accepted January 31, 2017
  • Published online March 20, 2017.
Copyright & Usage 
Copyright © 2017 Moyon et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Sarah Moyon1,*,
  2. Dan Ma4,*,
  3. Jimmy L. Huynh1,2,
  4. David J.C. Coutts4,
  5. Chao Zhao4,
  6. Patrizia Casaccia1,2,3 and
  7. Robin J.M. Franklin4
  1. 1Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029
  2. 2Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029
  3. 3Neuroscience Initiative Advanced Science Research Center, CUNY, New York, NY 10031
  4. 4Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute and Department of Clinical Neurosciences, University of Cambridge, Cambridge, CB2 0AH, UK
  1. Correspondence should be addressed to either of the following: Sarah Moyon. E-mail: sarah.moyon{at}mssm.edu; or Robin J. M. Franklin. E-mail: rjf1000{at}cam.ac.uk.
View Full Text

Author contributions

  1. Author contributions: P.C. and R.J.M.F. designed the research; D.M., S.M., J.L.H., D.J.J.C., and C.Z. performed the research; D.M., S.M., C.Z., P.C., and R.J.M.F. analyzed the data; S.M. wrote the paper with input from other authors.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by NIH-R37NS42925-14 to P.C., NIH-F31NS077504 Fellowship to J.L.H., postdoctoral fellowships from the Paralyzed Veterans of America (3061) and National Multiple Sclerosis Society (FG-1507-04996) to S.M., a program grant from the UK Multiple Sclerosis Society (R.J.M.F., C.Z.) and a core support grant from the Wellcome Trust and MRC to the Wellcome Trust – Medical Research Council Cambridge Stem Cell Institute (R.J.M.F.).

  • ↵* S.M. and D.M. are co-first authors.

Funding

  • NIH

    NIH-R37NS42925-14
  • NIH

    NIH-F31NS077504
  • UK Multiple Sclerosis Society

  • Paralyzed Veterans of America Research Foundation (PVA Research Foundation)

    100001810; 3061
  • National Multiple Sclerosis Society (National MS Society)

    100000890; FG-1507-04996

Other Version

  • You are viewing the most recent version of this article.
  • previous version (March 20, 2017).

Online Impact

 

Article usage

Select a custom date range for the past year
E.g., 2023-12-06
to
E.g., 2023-12-06

Article usage: April 2017 to December 2023

AbstractFullPdf
Apr 2017255
May 20173997100
Jun 2017143446
Jul 2017113339
Aug 2017336447
Sep 2017319152
Oct 20173710373
Nov 2017249259
Dec 2017422514
Total 2017233544435
Jan 2018343513
Feb 2018184018
Mar 2018102920
Apr 2018228950
May 2018166031
Jun 2018115139
Jul 201893823
Aug 201884842
Sep 201862614
Oct 201854510
Nov 2018514911
Dec 20181112511
Total 2018155735282
Jan 2019615414
Feb 201991188
Mar 20193886
Apr 20194468
May 201983914
Jun 201943813
Jul 201963415
Aug 201942715
Oct 201966313
Nov 20194307
Dec 2019116120
Total 201965698133
Jan 202043712
Feb 202034024
Mar 202003814
May 202032510
Jun 202014214
Jul 20203319
Aug 20200226
Sep 202023720
Oct 202036115
Nov 202015413
Dec 202066010
Total 202026447147
Jan 20213369
Feb 20218383
Mar 202145420
Apr 20211456
May 20216566
Jun 202146016
Jul 202174819
Aug 202111478
Sep 202135718
Oct 202115120
Nov 202116434
Dec 20211394
Total 202150595163
Jan 20222418
Feb 20223468
Mar 202234513
Apr 20220327
May 202226021
Jun 202265514
Jul 202263917
Aug 202212711
Sep 202232913
Oct 202243217
Nov 202263217
Dec 202204626
Total 202236484172
Jan 202335813
Feb 202314614
Mar 20230469
Apr 202304714
May 202324115
Jun 20230568
Jul 202335535
Aug 202359436
Sep 2023220920
Oct 2023729024
Nov 2023651930
Dec 20230105
Total 2023291471223
Total59449741555
Back to top

In this issue

eneuro: 4 (2)
eNeuro
Vol. 4, Issue 2
March/April 2017
  • Table of Contents
  • Index by author
Email

Thank you for sharing this eNeuro article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Efficient Remyelination Requires DNA Methylation
(Your Name) has forwarded a page to you from eNeuro
(Your Name) thought you would be interested in this article in eNeuro.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
Efficient Remyelination Requires DNA Methylation
Sarah Moyon, Dan Ma, Jimmy L. Huynh, David J.C. Coutts, Chao Zhao, Patrizia Casaccia, Robin J.M. Franklin
eNeuro 20 March 2017, 4 (2) ENEURO.0336-16.2017; DOI: 10.1523/ENEURO.0336-16.2017

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Share
Efficient Remyelination Requires DNA Methylation
Sarah Moyon, Dan Ma, Jimmy L. Huynh, David J.C. Coutts, Chao Zhao, Patrizia Casaccia, Robin J.M. Franklin
eNeuro 20 March 2017, 4 (2) ENEURO.0336-16.2017; DOI: 10.1523/ENEURO.0336-16.2017
Reddit logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Visual Abstract
    • Abstract
    • Significance Statement
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Footnotes
    • References
    • Synthesis
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • Adult Oligodendrocyte Progenitor Cells
  • DNA methylation
  • remyelination

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

New Research

  • Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) of the Bed Nucleus of the Stria Terminalis Mediates Heavy Alcohol Drinking in Mice
  • Internet-connected cortical organoids for project-based stem cell and neuroscience education
  • Modeling synaptic integration of bursty and beta oscillatory inputs in ventromedial motor thalamic neurons in normal and parkinsonian states
Show more New Research

Disorders of the Nervous System

  • Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) of the Bed Nucleus of the Stria Terminalis Mediates Heavy Alcohol Drinking in Mice
  • Elevated Serotonin in Mouse Spinal Dorsal Horn Is Pronociceptive
  • Tug-of-peace: Visual Rivalry and Atypical Visual Motion Processing in MECP2 duplication Syndrome of Autism
Show more Disorders of the Nervous System

Subjects

  • Disorders of the Nervous System

  • Home
  • Alerts
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Latest Articles
  • Issue Archive
  • Blog
  • Browse by Topic

Information

  • For Authors
  • For the Media

About

  • About the Journal
  • Editorial Board
  • Privacy Policy
  • Contact
  • Feedback
(eNeuro logo)
(SfN logo)

Copyright © 2023 by the Society for Neuroscience.
eNeuro eISSN: 2373-2822

The ideas and opinions expressed in eNeuro do not necessarily reflect those of SfN or the eNeuro Editorial Board. Publication of an advertisement or other product mention in eNeuro should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in eNeuro.