a | 1A, Seahorse-neuron-baseline | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.54 | 1 | 1 | 84.2 |
b | 1A, Seahorse-neuron-FCCP | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.69 | 1 | 1 | 171 |
c | 1A, Seahorse-neuron-rotenone | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.33 | 0.97 | 1 | 28.6 |
d | 1B, Seahorse-neuron-baseline | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.15 | 0.62 | 1 | 64.5 |
e | 1B, Seahorse neuron-oligomycin | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.16 | 0.68 | 1 | 26.8 |
f | 1B, Seahorse neuron-rotenone | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.17 | 0.71 | 1 | 16.8 |
g | 1C, Seahorse neuron pre- veratridine | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.13 | 0.53 | 0.98 | 60 |
h | 1C, Seahorse neuron post- veratridine | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.13 | 0.54 | 0.98 | 83 |
i | 1D, Seahorse neuron pre- oligomycin | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.2 | 0.79 | 1 | 70.5 |
j | 1D, Seahorse neuron post- oligomycin | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.28 | 0.93 | 1 | 97.5 |
k | 1E, Seahorse, cortical synaptosomes-baseline | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.31 | 0.95 | 1 | 77.5 |
l | 1E, Seahorse, cortical synaptosomes-FCCP | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.16 | 0.68 | 1 | 235 |
m | 1E, cortical synaptosomes- rotenone | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.08 | 0.3 | 0.82 | 15 |
n | 1F, DA synaptosomes-baseline | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.14 | 0.6 | 0.99 | 63.5 |
o | 1F, DA synaptosomes-FCCP | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.1 | 0.39 | 0.92 | 120 |
p | 1F, DA synaptosomes-rotenone | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.05 | 0.13 | 0.37 | 0 |
q | 2A, baseline ATP sensor | Normal | Unpaired Student’s t-test (two-tailed) | 0.23 | 0.87 | 1 | 2 |
r | 2B, poststim1-imagea | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.97 | 1 | 1 | 77.2 |
s | 2B, poststim1-Imageb | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.56 | 1 | 1 | 74.8 |
t | 2B, poststim2-imagea | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.41 | 0.99 | 1 | 66 |
u | 2B, poststim2-imageb | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.75 | 1 | 1 | 70.5 |
v | 2C, poststim1-imagea | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.89 | 1 | 1 | 74.6 |
w | 2C, poststim1-Imageb | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.99 | 1 | 1 | 85.1 |
x | 2C, poststim2-imagea | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.82 | 1 | 1 | 65.9 |
y | 2C, poststim2-imageb | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.93 | 1 | 1 | 63.8 |
z | 2D, synKO pHluorin-stim1 | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.51 | 1 | 1 | 0.794 |
aa | 2D, synKO pHluorin-stim2 | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.3 | 0.95 | 1 | 0.718 |
ab | 2E, syn knockdown level | Normal | Unpaired Student’s t-test (two-tailed) | 0.28 | 0.93 | 1 | 76.5 |
ac | 2F, syn shRNA pHluorin-stim 1 | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.07 | 0.23 | 0.7 | 0.38 |
ad | 2F, syn shRNA pHluorin-stim 2 | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.85 | 1 | 1 | 0.932 |
ae | 3A, syn TKO ATP sensor | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.21 | 0.82 | 1 | 0.645 |
af | 3D, syn TKO pHluorin | Normal | Unpaired Student’s t-test (two-tailed) | 0.32 | 0.96 | 1 | 2.93 |
ag | 4B, syn KO mito boutons 4 months | Normal | Unpaired Student’s t-test (two-tailed) | 0.42 | 0.99 | 1 | 47.5 |
ah | 4B, syn KO mito boutons 8 months | Normal | Unpaired Student’s t-test (two-tailed) | 1 | 1 | 1 | 54.1 |
ai | 4C, Western αsyn | Normal | One-way ANOVA, Dunnett’s post hoc test | 0.6 | 1 | 1 | 85.2 |
aj | 4C, Western βsyn | Normal | One-way ANOVA, Dunnett’s post hoc test | 0.05 | 0.13 | 0.37 | 1 |
ak | 4E, shRNA syn level in vivo | Normal | Unpaired Student’s t-test (two-tailed) | 1 | 1 | 1 | 75.4 |
al | 4F, stereology | Normal | Unpaired Student’s t-test (two-tailed) | 0.47 | 1 | 1 | 0.715 |
am | 4G, shRNA mito boutons | Normal | Unpaired Student’s t-test (two-tailed) | 0.72 | 1 | 1 | 50.5 |
an | 5A, lean body mass | Normal | Two-way ANOVA, Sidak’s post hoc test | 1 | 1 | 1 | 20.1 |
ao | 5A, fat body mass | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.39 | 0.99 | 1 | 2.58 |
ap | 5B, food intake | Normal | Unpaired Student’s t-test (two-tailed) | 0.42 | 0.99 | 1 | 4 |
aq | 5C, activity light cycle | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.06 | 0.18 | 0.54 | 53 |
ar | 5C, activity dark cycle | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.09 | 0.36 | 0.9 | 360 |
as | 5D, VO2 light cycle | Normal | Two-way ANOVA, Sidak’s post hoc test | 1 | 1 | 1 | 2.99 |
at | 5D, VO2 dark cycle | Normal | Two-way ANOVA, Sidak’s post hoc test | 1 | 1 | 1 | 3.64 |
au | 5E, VCO2 light cycle | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.1 | 0.4 | 0.93 | 1.68 |
av | 5E, VCO2 dark cycle | Normal | Two-way ANOVA, Sidak’s post hoc test | 0.1 | 0.4 | 0.93 | 1.68 |
aw | 5F, RER light cycle | Normal | Two-way ANOVA, Sidak’s post hoc test | 1 | 1 | 1 | 0.829 |
ax | 5F, RER dark cycle | Normal | Two-way ANOVA, Sidak’s post hoc test | 1 | 1 | 1 | 0.853 |