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Review, Development

Development and Organization of the Evolutionarily Conserved Three-Layered Olfactory Cortex

Esther Klingler
eNeuro 20 January 2017, 4 (1) ENEURO.0193-16.2016; https://doi.org/10.1523/ENEURO.0193-16.2016
Esther Klingler
Department of Basic Neuroscience, University of Geneva, 1211 Geneva 4, Switzerland
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    Figure 1.

    Early migration routes to the olfactory cortex (E10–E12). OCx, Olfactory cortex; PC, piriform cortex; OT, olfactory tubercle; vLGE, ventrolateral ganglionic eminence; SES, septoeminential sulcus; RDT, rostromedial telencephalon; MDT, mediodorsal telencephalon; CDT, caudodorsal telencephalon; RMTW, rostromedial telencephalic wall. In blue, OT migrating neurons; in red, PC migrating neurons. Adapted from Garcia-Moreno et al., 2008, with permission.

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    Figure 2.

    Comparison of developing neocortex and piriform cortex. A, Main migratory routes to the neocortex and to the piriform cortex. i, Lateral cortical stream and modes of migration to the piriform cortex. B, Prenatal development of layers in the neocortex and in the piriform cortex illustrated by cresyl violet stainings. Cx, neocortex; OCx, olfactory cortex; Hip, hippocampus; ECM, extracellular matrix; MZ, marginal zone; CP, cortical plate; SP, subplate; SVZ, subventricular zone; IZ, intermediate zone; WM, white matter; L, layer; str, striatum; *anterior commissure. Scale bars, 200 µm.

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    Figure 3.

    Piriform cortex neuron identities. A, Expression of principal neocortical layer markers in the piriform cortex. In situ hybridizations from Allen Brain Atlas database (postnatal day 56). CC, Corpus callosum; AC, anterior commissure; Str, striatum; L, layer. Scale bar, 200 µm. B, Organization, molecular identities, and known targets of projection neurons in the piriform cortex. LOT, lateral olfactory tract; CoA, cortical amygdala; lENT, lateral entorhinal cortex; OB, olfactory bulb; IL-mPFC, infralimbic medial prefrontal cortex.

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eneuro: 4 (1)
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January/February 2017
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Development and Organization of the Evolutionarily Conserved Three-Layered Olfactory Cortex
Esther Klingler
eNeuro 20 January 2017, 4 (1) ENEURO.0193-16.2016; DOI: 10.1523/ENEURO.0193-16.2016

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Development and Organization of the Evolutionarily Conserved Three-Layered Olfactory Cortex
Esther Klingler
eNeuro 20 January 2017, 4 (1) ENEURO.0193-16.2016; DOI: 10.1523/ENEURO.0193-16.2016
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  • Article
    • Abstract
    • Significance Statement
    • Introduction
    • Arealization and neurogenesis
    • Migration and layer formation
    • Cell types and organization of the circuit implicated in odor processing
    • Concluding remarks
    • Acknowledgments
    • Footnotes
    • References
    • Synthesis
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Keywords

  • cell identity
  • cortical layers
  • migration
  • neocortex
  • neurogenesis
  • olfactory cortex

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