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Research ArticleNew Research, Disorders of the Nervous System

Alterations in Cytosolic and Mitochondrial [U-13C]Glucose Metabolism in a Chronic Epilepsy Mouse Model

Tanya S. McDonald, Catalina Carrasco-Pozo, Mark P. Hodson and Karin Borges
eNeuro 10 February 2017, 4 (1) ENEURO.0341-16.2017; DOI: https://doi.org/10.1523/ENEURO.0341-16.2017
Tanya S. McDonald
1Department of Pharmacology, School of Biomedical Sciences, University of Queensland, St. Lucia, QLD 4072, Australia
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Catalina Carrasco-Pozo
1Department of Pharmacology, School of Biomedical Sciences, University of Queensland, St. Lucia, QLD 4072, Australia
2Department of Nutrition, Faculty of Medicine, University of Chile, Santiago 8380453, Chile
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Mark P. Hodson
2Department of Nutrition, Faculty of Medicine, University of Chile, Santiago 8380453, Chile
3Metabolomics Australia, Australian Institute for Bioengineering and Nanotechnology, the University of Queensland, St. Lucia, QLD 4072, Australia
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Karin Borges
1Department of Pharmacology, School of Biomedical Sciences, University of Queensland, St. Lucia, QLD 4072, Australia
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0341-16.2017
PubMed 
28303258
Published By 
Society for Neuroscience
History 
  • Received November 14, 2016
  • Revision received January 10, 2017
  • Accepted January 16, 2017
  • Published online February 10, 2017.
Copyright & Usage 
Copyright © 2017 McDonald et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Tanya S. McDonald1,
  2. Catalina Carrasco-Pozo1,2,
  3. Mark P. Hodson2,3 and
  4. Karin Borges1
  1. 1Department of Pharmacology, School of Biomedical Sciences, University of Queensland, St. Lucia, QLD 4072, Australia
  2. 2Department of Nutrition, Faculty of Medicine, University of Chile, Santiago 8380453, Chile
  3. 3Metabolomics Australia, Australian Institute for Bioengineering and Nanotechnology, the University of Queensland, St. Lucia, QLD 4072, Australia
  4. 4School of Pharmacy, the University of Queensland, QLD 4072, St. Lucia, QLD 4072, Australia
  1. Correspondence should be addressed to Tanya S. McDonald, Department of Pharmacology, School of Biomedical Sciences, Skerman Building 65, St Lucia, QLD 4072, Australia. E-mail: tanya.mcdonald{at}uqconnect.edu.au.
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Author contributions

  1. Author contributions: T.S.M. and K.B. designed research; T.S.M., C.C.-P., and M.P.H. performed research; T.S.M., C.C.-P., and M.P.H. analyzed data; T.S.M., C.C.-P., M.P.H., and K.B. wrote the paper.

Disclosures

  • Authors report no conflict of interest

  • Department of Health, National Health and Medical Research Council (NHMRC) 1044007 to K.B.; Fondecyt Initiation into Research Grant 11130232 to C.C.-P.; APA Scholarship to T.S.M.

Other Version

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Feb 2017189099
Mar 201710810484
Apr 2017979983
May 2017647539
Jun 2017294435
Jul 2017283731
Aug 2017143725
Sep 2017365339
Oct 2017418863
Nov 2017258645
Dec 201718388
Total 2017649661551
Jan 201812389
Feb 2018124113
Mar 2018115018
Apr 2018247647
May 201886517
Jun 201875424
Jul 2018123613
Aug 2018226434
Sep 201859112
Oct 2018913310
Nov 20181217513
Dec 2018111183
Total 2018145941213
Jan 2019415119
Feb 2019815612
Mar 2019119018
Apr 2019616924
May 2019012816
Jun 2019410429
Jul 2019519619
Aug 20191541615
Sep 2019367613
Oct 2019380517
Nov 2019768022
Dec 2019684021
Total 2019624511225
Jan 2020833921
Feb 2020221922
Mar 2020217317
Apr 2020010024
May 2020218834
Jun 202056113
Jul 2020211221
Aug 202046712
Sep 2020412016
Oct 2020212726
Nov 202026816
Dec 2020416521
Total 2020371739243
Jan 2021228126
Feb 202119323
Mar 2021040
Total 2021337849
Total89682301281
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Alterations in Cytosolic and Mitochondrial [U-13C]Glucose Metabolism in a Chronic Epilepsy Mouse Model
Tanya S. McDonald, Catalina Carrasco-Pozo, Mark P. Hodson, Karin Borges
eNeuro 10 February 2017, 4 (1) ENEURO.0341-16.2017; DOI: 10.1523/ENEURO.0341-16.2017

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Alterations in Cytosolic and Mitochondrial [U-13C]Glucose Metabolism in a Chronic Epilepsy Mouse Model
Tanya S. McDonald, Catalina Carrasco-Pozo, Mark P. Hodson, Karin Borges
eNeuro 10 February 2017, 4 (1) ENEURO.0341-16.2017; DOI: 10.1523/ENEURO.0341-16.2017
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Keywords

  • glucose
  • Glycolysis
  • metabolism
  • mitochondria
  • seizure
  • TCA cycle

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