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Research ArticleNew Research, Disorders of the Nervous System

The Role of Sirt1 in Epileptogenesis

Alicia M. Hall, Gary P. Brennan, Tiffany M. Nguyen, Akanksha Singh-Taylor, Hyun-Seung Mun, Mary J. Sargious and Tallie Z. Baram
eNeuro 30 January 2017, 4 (1) ENEURO.0301-16.2017; https://doi.org/10.1523/ENEURO.0301-16.2017
Alicia M. Hall
1Department of Pediatrics, University of California, Irvine, Irvine, California 92697
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Gary P. Brennan
1Department of Pediatrics, University of California, Irvine, Irvine, California 92697
2Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, California 92697
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Tiffany M. Nguyen
1Department of Pediatrics, University of California, Irvine, Irvine, California 92697
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Akanksha Singh-Taylor
1Department of Pediatrics, University of California, Irvine, Irvine, California 92697
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Hyun-Seung Mun
1Department of Pediatrics, University of California, Irvine, Irvine, California 92697
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Mary J. Sargious
1Department of Pediatrics, University of California, Irvine, Irvine, California 92697
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Tallie Z. Baram
1Department of Pediatrics, University of California, Irvine, Irvine, California 92697
2Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, California 92697
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0301-16.2017
PubMed 
28197553
Published By 
Society for Neuroscience
History 
  • Received October 7, 2016
  • Revision received January 21, 2017
  • Accepted January 22, 2017
  • Published online January 30, 2017.
Copyright & Usage 
Copyright © 2017 Hall et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Alicia M. Hall1,
  2. Gary P. Brennan1,2,
  3. Tiffany M. Nguyen1,
  4. Akanksha Singh-Taylor1,
  5. Hyun-Seung Mun1,
  6. Mary J. Sargious1 and
  7. Tallie Z. Baram1,2
  1. 1Department of Pediatrics, University of California, Irvine, Irvine, California 92697
  2. 2Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, California 92697
  1. Correspondence should be addressed to Tallie Z. Baram, Department of Pediatrics, University of California, Irvine, Irvine, CA 92697. E-mail: tallie{at}uci.edu.
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Author contributions

  1. Author contributions: A.M.H. G.P.B., and T.Z.B. designed research; A.M.H, T.M.N, A.S.-T., H.-S.M., and M.J.S. performed research. A.M.H. and T.Z.B. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by National Institutes of Health grants NS-35439 and NS-78279.

Funding

  • national institute of neurological disorders NINDS

    NS35439
  • NIH

    NS 78279
  • Hewitt biomedical foundation

Other Version

  • You are viewing the most recent version of this article.
  • previous version (January 30, 2017).

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Apr 202524815
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Total 202541425167
Total58985652047
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The Role of Sirt1 in Epileptogenesis
Alicia M. Hall, Gary P. Brennan, Tiffany M. Nguyen, Akanksha Singh-Taylor, Hyun-Seung Mun, Mary J. Sargious, Tallie Z. Baram
eNeuro 30 January 2017, 4 (1) ENEURO.0301-16.2017; DOI: 10.1523/ENEURO.0301-16.2017

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The Role of Sirt1 in Epileptogenesis
Alicia M. Hall, Gary P. Brennan, Tiffany M. Nguyen, Akanksha Singh-Taylor, Hyun-Seung Mun, Mary J. Sargious, Tallie Z. Baram
eNeuro 30 January 2017, 4 (1) ENEURO.0301-16.2017; DOI: 10.1523/ENEURO.0301-16.2017
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Keywords

  • epigenetics
  • epilepsy
  • epileptogenesis
  • intervention
  • metabolic stress
  • sirtuins

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