Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT

User menu

Search

  • Advanced search
eNeuro

eNeuro

Advanced Search

 

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT
PreviousNext
Research ArticleNew Research, Cognition and Behavior

Circadian Forced Desynchrony of the Master Clock Leads to Phenotypic Manifestation of Depression in Rats

Miriam Ben-Hamo, Tracy A. Larson, Leanne S. Duge, Carl Sikkema, Charles W. Wilkinson, Horacio O. de la Iglesia and Mónica M. C. González
eNeuro 5 December 2016, 3 (6) ENEURO.0237-16.2016; DOI: https://doi.org/10.1523/ENEURO.0237-16.2016
Miriam Ben-Hamo
1Department of Biology
2Program in Neuroscience, University of Washington, Seattle, WA 98195
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Miriam Ben-Hamo
Tracy A. Larson
1Department of Biology
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Tracy A. Larson
Leanne S. Duge
1Department of Biology
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Leanne S. Duge
Carl Sikkema
3Geriatric Research, Education and Clinical Center, VA Puget Sound Health Care System, Seattle, WA 98108
4Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Charles W. Wilkinson
3Geriatric Research, Education and Clinical Center, VA Puget Sound Health Care System, Seattle, WA 98108
4Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Charles W. Wilkinson
Horacio O. de la Iglesia
1Department of Biology
2Program in Neuroscience, University of Washington, Seattle, WA 98195
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Horacio O. de la Iglesia
Mónica M. C. González
1Department of Biology
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Mónica M. C. González
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/ENEURO.0237-16.2016
PubMed 
28090585
Published By 
Society for Neuroscience
History 
  • Received August 11, 2016
  • Revision received November 23, 2016
  • Accepted November 28, 2016
  • Published online December 5, 2016.
Copyright & Usage 
Copyright © 2016 Ben-Hamo et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Miriam Ben-Hamo1,2,
  2. Tracy A. Larson1,
  3. Leanne S. Duge1,
  4. Carl Sikkema3,4,
  5. Charles W. Wilkinson3,4,
  6. Horacio O. de la Iglesia1,2 and
  7. Mónica M. C. González1
  1. 1Department of Biology
  2. 2Program in Neuroscience, University of Washington, Seattle, WA 98195
  3. 3Geriatric Research, Education and Clinical Center, VA Puget Sound Health Care System, Seattle, WA 98108
  4. 4Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195
  1. Correspondence should be addressed to either of the following: Horacio O. de la Iglesia, E-mail: horaciod{at}uw.edu; or Mónica M. C. González, E-mail: mgonzalez{at}ifn.com.ar. Horacio O. de la Iglesia, Department of Biology, University of Washington, Seattle, WA 98195-1800, USA. Mónica M. González, Instituto Ferrero de Neurología y Sueño (IFN), Junín 1120-CABA, Argentina.
  • Mónica M. C. González’s present address is Instituto Ferrero de Neurología y Sueño, Buenos Aires, Argentina.

  • Tracy A. Larson's present address is Department of Biology, University of Virginia, Charlottesville.

View Full Text

Author contributions

  1. Author contributions: MB-H, TAL, HOD, and MMCG designed research, performed research, analyzed data and wrote the paper. CWW performed research and wrote the paper. LSD and CS performed research.

  • Mónica M. C. González’s present address is Instituto Ferrero de Neurología y Sueño, Buenos Aires, Argentina.

  • Tracy A. Larson's present address is Department of Biology, University of Virginia, Charlottesville.

Disclosures

  • The authors declare no competing financial interests.

  • Supported by HHS, National Institutes of Health [R01MH075016 R01NS094211]; National Science Foundation [IOS0909716]; National Alliance for Research on Schizophrenia and Depression [Young Investigator Award]; Israeli Committee for Higher Education [Postdoctoral Fellowship for Women]; Washington Research Foundation Innovation postdoctoral fellowship in Neuroengineering]; Geriatric Research, Education and Clinical Center, and the Research and Development Service of the VA Puget Sound Health Care System.

Funding

  • HHS | National Institutes of Health (NIH)

    100000002; R01MH075016
  • National Science Foundation (NSF)

    100000001; IOS0909716
  • National Alliance for Research on Schizophrenia and Depression (NARSAD)

    100009670; Young Investigator Award
  • Israeli Committee for Higher Education

    Postdoctoral Fellowship for Women
  • Washington Research Foundation (WRF)

    100001906; Postdoctoral Fellowship for Innovation in Neuroengineering
  • HHS | National Institutes of Health (NIH)

    100000002; R01NS094211
  • Geriatric Research and Clinical Center, and the Research and Development Service, VA Puget Sound Health Care System

Other Version

  • previous version (December 05, 2016).
  • You are viewing the most recent version of this article.

Online Impact

 

Article usage

Select a custom date range for the past year
E.g., 2022-06-23
to
E.g., 2022-06-23

Article usage: December 2016 to May 2022

AbstractFullPdf
Dec 2016180079
Total 2016180079
Jan 201747382135
Feb 20171114736
Mar 20173310930
Apr 2017648952
May 2017469460
Jun 2017378228
Jul 2017244330
Aug 2017214340
Sep 2017327336
Oct 2017387254
Nov 2017456841
Dec 2017342710
Total 20174321229552
Jan 2018393018
Feb 2018202719
Mar 201818179
Apr 20181313758
May 20181230311
Jun 20182536545
Jul 2018171347
Aug 201897345
Sep 201813597
Oct 20181418722
Nov 20181822713
Dec 20181520613
Total 20182131765267
Jan 2019717411
Feb 201951688
Mar 201971419
Apr 201969615
May 201937617
Jun 2019103215
Jul 201984716
Aug 201983711
Sep 201933010
Oct 201963610
Nov 20196408
Dec 201945133
Total 201973928163
Jan 202035013
Feb 202032424
Mar 202044215
Apr 202073311
May 202023911
Jun 20205237
Jul 20205355
Aug 202056613
Sep 202065212
Oct 202087616
Nov 202056112
Dec 2020410614
Total 202057607153
Jan 20213598
Feb 202177427
Mar 202149814
Apr 202135710
May 202126213
Jun 20210517
Jul 202145816
Aug 202175118
Sep 202118513
Oct 202186328
Nov 202128230
Dec 20211614
Total 202142801188
Jan 202216220
Feb 20222388
Mar 202209829
Apr 202214823
May 202226917
Total 2022631597
Total100356451499
Back to top

In this issue

eneuro: 3 (6)
eNeuro
Vol. 3, Issue 6
November/December 2016
  • Table of Contents
  • Index by author
Email

Thank you for sharing this eNeuro article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Circadian Forced Desynchrony of the Master Clock Leads to Phenotypic Manifestation of Depression in Rats
(Your Name) has forwarded a page to you from eNeuro
(Your Name) thought you would be interested in this article in eNeuro.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
Circadian Forced Desynchrony of the Master Clock Leads to Phenotypic Manifestation of Depression in Rats
Miriam Ben-Hamo, Tracy A. Larson, Leanne S. Duge, Carl Sikkema, Charles W. Wilkinson, Horacio O. de la Iglesia, Mónica M. C. González
eNeuro 5 December 2016, 3 (6) ENEURO.0237-16.2016; DOI: 10.1523/ENEURO.0237-16.2016

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Share
Circadian Forced Desynchrony of the Master Clock Leads to Phenotypic Manifestation of Depression in Rats
Miriam Ben-Hamo, Tracy A. Larson, Leanne S. Duge, Carl Sikkema, Charles W. Wilkinson, Horacio O. de la Iglesia, Mónica M. C. González
eNeuro 5 December 2016, 3 (6) ENEURO.0237-16.2016; DOI: 10.1523/ENEURO.0237-16.2016
del.icio.us logo Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Visual Abstract
    • Abstract
    • Significance Statement
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments
    • Footnotes
    • References
    • Synthesis
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • behavior
  • circadian rhythms
  • depression
  • emotion
  • rat

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

New Research

  • Granule cells constitute one of the major neuronal subtypes in the molecular layer of the posterior cerebellum
  • AGING-ASSOCIATED COGNITIVE DECLINE IS REVERSED BY D-SERINE SUPPLEMENTATION
  • Histochemical characterization of the dorsal raphe-periaqueductal grey dopamine transporter neurons projecting to the extended amygdala
Show more New Research

Cognition and Behavior

  • AGING-ASSOCIATED COGNITIVE DECLINE IS REVERSED BY D-SERINE SUPPLEMENTATION
  • Auditory cortex neurons show task-related and learning-dependent selectivity toward sensory input and reward during the learning process of an associative memory task
  • Functional Gradient of the Fusiform Cortex for Chinese Character Recognition
Show more Cognition and Behavior

Subjects

  • Cognition and Behavior

  • Home
  • Alerts
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Latest Articles
  • Issue Archive
  • Blog
  • Browse by Topic

Information

  • For Authors
  • For the Media

About

  • About the Journal
  • Editorial Board
  • Privacy Policy
  • Contact
  • Feedback
(eNeuro logo)
(SfN logo)

Copyright © 2022 by the Society for Neuroscience.
eNeuro eISSN: 2373-2822

The ideas and opinions expressed in eNeuro do not necessarily reflect those of SfN or the eNeuro Editorial Board. Publication of an advertisement or other product mention in eNeuro should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in eNeuro.