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Research ArticleNew Research, Integrative Systems

Noradrenaline from Locus Coeruleus Neurons Acts on Pedunculo-Pontine Neurons to Prevent REM Sleep and Induces Its Loss-Associated Effects in Rats

Mudasir Ahmad Khanday, Bindu I. Somarajan, Rachna Mehta and Birendra Nath Mallick
eNeuro 30 November 2016, 3 (6) ENEURO.0108-16.2016; DOI: https://doi.org/10.1523/ENEURO.0108-16.2016
Mudasir Ahmad Khanday
School of Life Sciences, Jawaharlal Nehru University, New Delhi 110607, India
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Bindu I. Somarajan
School of Life Sciences, Jawaharlal Nehru University, New Delhi 110607, India
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Rachna Mehta
School of Life Sciences, Jawaharlal Nehru University, New Delhi 110607, India
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Birendra Nath Mallick
School of Life Sciences, Jawaharlal Nehru University, New Delhi 110607, India
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0108-16.2016
PubMed 
27957531
Published By 
Society for Neuroscience
History 
  • Received May 4, 2016
  • Revision received October 2, 2016
  • Accepted October 4, 2016
  • Published online November 30, 2016.
Copyright & Usage 
Copyright © 2016 Khanday et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Mudasir Ahmad Khanday,
  2. Bindu I. Somarajan,
  3. Rachna Mehta and
  4. Birendra Nath Mallick
  1. School of Life Sciences, Jawaharlal Nehru University, New Delhi 110607, India
  1. Correspondence should be addressed to Birendra Nath Mallick, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India. E-mail: remsbnm{at}yahoo.com.
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Author contributions

  1. Author Contributions: B.N.M. designed research; M.A.K., B.I.S., and R.M. performed research; M.A.K., B.I.S., and R.M. analyzed data; M.A.K. and B.N.M. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This research was supported by a J C Bose Fellowship (to BNM); the Department of Science & Technology (DST), Government of India; University Grants Commission (UGC; fellowship to M.A.K.) and Institutional Grants to the Jawaharlal Nehru University under a DST Promotion of University Research and Scientific Excellence and Fund for Improvement of S&T Infrastructure; the Department of Biotechnology BUILDER Programme and UGC-Universities With Potential For Excellence, Departmental Research Support and Resource Networking India.

Funding

  • Institutional Grant to the University from Department of Science and Technology under PURSE and FIST programs

  • Institutional Grant to the University from Department of Biotechnology under BUILDER program

  • Institutional Grant to the University from University Grants Commission under UPE, DRS and Networking programs

  • University Grants Commission (UGC)

    501100001501
  • J. C. Bose Fellowship

Other Version

  • You are viewing the most recent version of this article.
  • previous version (November 30, 2016).

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November/December 2016
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Noradrenaline from Locus Coeruleus Neurons Acts on Pedunculo-Pontine Neurons to Prevent REM Sleep and Induces Its Loss-Associated Effects in Rats
Mudasir Ahmad Khanday, Bindu I. Somarajan, Rachna Mehta, Birendra Nath Mallick
eNeuro 30 November 2016, 3 (6) ENEURO.0108-16.2016; DOI: 10.1523/ENEURO.0108-16.2016

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Noradrenaline from Locus Coeruleus Neurons Acts on Pedunculo-Pontine Neurons to Prevent REM Sleep and Induces Its Loss-Associated Effects in Rats
Mudasir Ahmad Khanday, Bindu I. Somarajan, Rachna Mehta, Birendra Nath Mallick
eNeuro 30 November 2016, 3 (6) ENEURO.0108-16.2016; DOI: 10.1523/ENEURO.0108-16.2016
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Keywords

  • inhibition
  • REM-OFF/REM-ON neurons
  • REMS deprivation
  • REMS generation
  • RNAi
  • tyrosine hydroxylase

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