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Research ArticleNew Research, Neuronal Excitability

SLC26A11 (KBAT) in Purkinje Cells Is Critical for Inhibitory Transmission and Contributes to Locomotor Coordination

Negah Rahmati, Maria Fernanda Vinueza Veloz, Jie Xu, Sharon Barone, Nahuel Rodolfo Ben Hamida, Martijn Schonewille, Freek E. Hoebeek, Manoocher Soleimani and Chris I. De Zeeuw
eNeuro 1 June 2016, 3 (3) ENEURO.0028-16.2016; DOI: https://doi.org/10.1523/ENEURO.0028-16.2016
Negah Rahmati
1Department of Neuroscience, Erasmus MC, 3000 CA Rotterdam, The Netherlands
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  • ORCID record for Negah Rahmati
Maria Fernanda Vinueza Veloz
1Department of Neuroscience, Erasmus MC, 3000 CA Rotterdam, The Netherlands
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Jie Xu
2Department of Medicine, University of Cincinnati, Cincinnati, OH 45267
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Sharon Barone
2Department of Medicine, University of Cincinnati, Cincinnati, OH 45267
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Nahuel Rodolfo Ben Hamida
1Department of Neuroscience, Erasmus MC, 3000 CA Rotterdam, The Netherlands
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Martijn Schonewille
1Department of Neuroscience, Erasmus MC, 3000 CA Rotterdam, The Netherlands
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Freek E. Hoebeek
1Department of Neuroscience, Erasmus MC, 3000 CA Rotterdam, The Netherlands
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Manoocher Soleimani
2Department of Medicine, University of Cincinnati, Cincinnati, OH 45267
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Chris I. De Zeeuw
1Department of Neuroscience, Erasmus MC, 3000 CA Rotterdam, The Netherlands
3Netherlands Institute for Neuroscience, 1105 BA, Amsterdam, The Netherlands
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0028-16.2016
PubMed 
27390771
Published By 
Society for Neuroscience
History 
  • Received February 11, 2016
  • Revision received May 21, 2016
  • Accepted May 24, 2016
  • Published online June 1, 2016.
Copyright & Usage 
Copyright © 2016 Rahmati et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Negah Rahmati1,
  2. Maria Fernanda Vinueza Veloz1,
  3. Jie Xu2,
  4. Sharon Barone2,
  5. Nahuel Rodolfo Ben Hamida1,
  6. Martijn Schonewille1,
  7. Freek E. Hoebeek1,
  8. Manoocher Soleimani2 and
  9. Chris I. De Zeeuw1,3
  1. 1Department of Neuroscience, Erasmus MC, 3000 CA Rotterdam, The Netherlands
  2. 2Department of Medicine, University of Cincinnati, Cincinnati, OH 45267
  3. 3Netherlands Institute for Neuroscience, 1105 BA, Amsterdam, The Netherlands
  1. Correspondence should be addressed to either of the following: Chris I. De Zeeuw, Department of Neuroscience, Erasmus MC, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands, E-mail: c.dezeeuw{at}erasmusmc.nl; or Manoocher Soleimani, Department of Medicine, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267, Email: soleimm{at}ucmail.uc.edu.
  2. N. Rahmati’s present address: Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02129.
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Author contributions

  1. ↵2 Author contributions: N.R., F.E.H., M. Soleimani, and C.I.D.Z. designed research; N.R., M.F.V.V., J.X., S.B., and N.R.B.H. performed research; N.R., M.F.V.V., J.X., S.B., N.R.B.H., and M. Schonewille analyzed data; N.R., F.E.H., M. Soleimani, and C.I.D.Z. wrote the paper.

Disclosures

  • ↵1 The authors declare no competing financial interests.

  • ↵3 This work was supported by the Dutch Organization for Medical Sciences (ZonMw Top-Go 912.100.00; C.I.D.Z.), Life Sciences (ALW 854.10.004; C.I.D.Z.), Senter (Neurobsik FES 0908 min VWS; C.I.D.Z.), the ERC-advanced and related ERC-POCs (294775), Cerebnet (238686 ITN), and C7 (238214 ITN) programs of the European Community (C.I.D.Z.); M. Soleimani was supported by Merit Review award 510BX001000-04 from the Department of Veterans Affairs, and funds from the Center on Genetics of Transport and Epithelial Biology at University of Cincinnati. We thank Mandy Rutteman and Elise Haasdijk for technical assistance.

Funding

  • Dutch Organization for Medical Sciences

    ZonMw Top-Go 912.100.00; C.I.D.Z.
  • Life Sciences

    ALW 854.10.004; C.I.D.Z.
  • Senter

    Neurobsik FES 0908 min VWS; C.I.D.Z.
  • The ERC-advanced

    294775
  • Cerebnet

    238686 ITN
  • C7 programs of the European community

    238214 ITN
  • Merit review award

    510BX001000-04 (M.Soleimani)

Other Version

  • You are viewing the most recent version of this article.
  • previous version (June 01, 2016).

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AbstractFullPdf
Jul 201603530
Aug 201603121
Sep 20160209
Oct 20160207
Nov 20160129
Dec 20160114
Total 2016012980
Jan 20170112
Feb 201702816
Mar 20170147
Apr 2017121617
May 201781416
Jun 201741211
Jul 20174109
Aug 201794014
Sep 2017125223
Oct 2017116214
Nov 2017236232
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Total 2017104375169
Jan 2018105113
Feb 2018104416
Mar 20189277
Apr 2018106617
May 201854415
Jun 2018136421
Jul 20183209
Aug 201832610
Sep 20185209
Oct 201883912
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Total 201891616139
Jan 20191282
Feb 20195454
Mar 20194454
Apr 201973111
May 20195168
Jun 20191258
Jul 20194183
Aug 20199189
Oct 20195192
Nov 201942510
Dec 201921912
Total 20194728973
Jan 202092810
Feb 202041819
Mar 2020194
May 20202138
Jun 20205174
Jul 20201142
Aug 20202138
Sep 202032210
Oct 20205485
Nov 202084721
Dec 202098320
Total 202049312111
Jan 202134724
Feb 202104612
Mar 20213427
Apr 20211446
May 20212456
Jun 20210492
Jul 202184913
Aug 202124812
Sep 20211457
Oct 202174325
Nov 202134243
Dec 20211470
Total 202131547157
Jan 202244514
Feb 20225335
Mar 20225309
Apr 20221397
May 202224314
Jun 20223405
Jul 20223287
Aug 20221368
Sep 202202511
Oct 202212811
Nov 20222348
Dec 202233316
Total 202230414115
Jan 202303910
Feb 20231396
Mar 20231283
Total 2023210619
Total3542788863
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SLC26A11 (KBAT) in Purkinje Cells Is Critical for Inhibitory Transmission and Contributes to Locomotor Coordination
Negah Rahmati, Maria Fernanda Vinueza Veloz, Jie Xu, Sharon Barone, Nahuel Rodolfo Ben Hamida, Martijn Schonewille, Freek E. Hoebeek, Manoocher Soleimani, Chris I. De Zeeuw
eNeuro 1 June 2016, 3 (3) ENEURO.0028-16.2016; DOI: 10.1523/ENEURO.0028-16.2016

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SLC26A11 (KBAT) in Purkinje Cells Is Critical for Inhibitory Transmission and Contributes to Locomotor Coordination
Negah Rahmati, Maria Fernanda Vinueza Veloz, Jie Xu, Sharon Barone, Nahuel Rodolfo Ben Hamida, Martijn Schonewille, Freek E. Hoebeek, Manoocher Soleimani, Chris I. De Zeeuw
eNeuro 1 June 2016, 3 (3) ENEURO.0028-16.2016; DOI: 10.1523/ENEURO.0028-16.2016
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Keywords

  • chloride Homeostasis
  • Chloride channel
  • GABAerg inhibition
  • cerebellum
  • Purkinje cell
  • locomotion

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