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Research ArticleMethods/New Tools, Novel Tools and Methods

Realistic Numerical and Analytical Modeling of Light Scattering in Brain Tissue for Optogenetic Applications

Guy Yona, Nizan Meitav, Itamar Kahn and Shy Shoham
eNeuro 4 January 2016, 3 (1) ENEURO.0059-15.2015; DOI: https://doi.org/10.1523/ENEURO.0059-15.2015
Guy Yona
1Autonomous Systems Program (TASP)
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Nizan Meitav
2Faculty of Biomedical Engineering
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Itamar Kahn
3Rappaport Faculty of Medicine and Institute, Technion - Israel Institute of Technology, Haifa, 31096, Israel
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Shy Shoham
2Faculty of Biomedical Engineering
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0059-15.2015
PubMed 
26866055
Published By 
Society for Neuroscience
History 
  • Received May 31, 2015
  • Revision received October 28, 2015
  • Accepted October 30, 2015
  • Published online January 4, 2016.
Copyright & Usage 
Copyright © 2016 Yona et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Guy Yona1,
  2. Nizan Meitav2,
  3. Itamar Kahn3 and
  4. Shy Shoham2
  1. 1Autonomous Systems Program (TASP)
  2. 2Faculty of Biomedical Engineering
  3. 3Rappaport Faculty of Medicine and Institute, Technion - Israel Institute of Technology, Haifa, 31096, Israel
  1. Correspondence should be addressed to Shy Shoham, Department of Biomedical Engineering, Technion - Israel Institute of Technology, Haifa 32000, Israel. E-mail: shy{at}technion.ac.il
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Author contributions

  1. ↵2 Contributions: G.Y., I.K., and S.S. designed research; G.Y. and N.M. performed research; G.Y. and S.S. analyzed data and wrote the paper.

Disclosures

  • ↵1 The authors report no conflict of interest.

  • ↵3 This work was supported by a grant from the Israel Ministry of Science, Technology and Space, ISF 225/11 (I.K.) and FP7-IRG PCIG9-GA-2011-294001 (I.K.), and G.Y. is supported in part by the Gutwirth Family fund. We thank Prof. Ofer Yizhar for helpful discussions, Dr Inbar Brosh for her technical assistance in producing the brain slices for the experiment, Shir Paluch for assistance with the BSF implementation, and Eliran Guzi and Dalia Rifold for writing the simulation GUI.

Funding

  • Israel Ministry of Science, Technology and Space

  • ISF

    225/11
  • FP7-IRG

    PCIG9-GA-2011-294001
  • Gutwirth Family fund

Other Version

  • You are viewing the most recent version of this article.
  • previous version (January 04, 2016).

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Realistic Numerical and Analytical Modeling of Light Scattering in Brain Tissue for Optogenetic Applications
Guy Yona, Nizan Meitav, Itamar Kahn, Shy Shoham
eNeuro 4 January 2016, 3 (1) ENEURO.0059-15.2015; DOI: 10.1523/ENEURO.0059-15.2015

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Realistic Numerical and Analytical Modeling of Light Scattering in Brain Tissue for Optogenetic Applications
Guy Yona, Nizan Meitav, Itamar Kahn, Shy Shoham
eNeuro 4 January 2016, 3 (1) ENEURO.0059-15.2015; DOI: 10.1523/ENEURO.0059-15.2015
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Keywords

  • beam-spread function
  • light scattering
  • Monte Carlo
  • optogenetics

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