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Research ArticleNew Research, Sensory and Motor Systems

Taste Bud-Derived BDNF Is Required to Maintain Normal Amounts of Innervation to Adult Taste Buds

Lingbin Meng, Lisa Ohman-Gault, Liqun Ma and Robin F. Krimm
eNeuro 22 December 2015, 2 (6) ENEURO.0097-15.2015; https://doi.org/10.1523/ENEURO.0097-15.2015
Lingbin Meng
Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky 40292
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Lisa Ohman-Gault
Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky 40292
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Liqun Ma
Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky 40292
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Robin F. Krimm
Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky 40292
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0097-15.2015
PubMed 
26730405
Published By 
Society for Neuroscience
History 
  • Received August 25, 2015
  • Revision received November 29, 2015
  • Accepted November 30, 2015
  • Published online December 22, 2015.
Copyright & Usage 
Copyright © 2015 Meng et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Lingbin Meng,
  2. Lisa Ohman-Gault,
  3. Liqun Ma and
  4. Robin F. Krimm
  1. Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, Louisville, Kentucky 40292
  1. Correspondence should be addressed to Dr Robin F. Krimm, Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine, HSC Building A, Room 1004, Louisville, KY 40292. E-mail: rfkrim01{at}louisville.edu.
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Author contributions

  1. ↵2 Contributions: L. Meng and R.F.K. designed research; L. Meng, L.O.-G., L. Ma, and R.F.K. performed research; L. Meng, L.O.-G., and R.F.K. analyzed data; L. Meng and R.F.K. wrote the paper.

Disclosures

  • ↵1 The authors declare no competing financial interests.

  • ↵3 This work was supported by National Institutes of Health Grant DC007176 (R.F.K) and DC006938 (David L. Hill). The statistical core facility, used for data analysis, is supported by NIH grant 8P30GM103507. We thank Darlene Burke for statistical support, and Dr David L. Hill and Dr Chengsan Sun for providing us with some tongue tissue.

Funding

  • NIDCD

    DC007176
  • NIDCD

    DC006938
  • NIH

    8P30GM103507

Other Version

  • You are viewing the most recent version of this article.
  • previous version (December 22, 2015).

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Taste Bud-Derived BDNF Is Required to Maintain Normal Amounts of Innervation to Adult Taste Buds
Lingbin Meng, Lisa Ohman-Gault, Liqun Ma, Robin F. Krimm
eNeuro 22 December 2015, 2 (6) ENEURO.0097-15.2015; DOI: 10.1523/ENEURO.0097-15.2015

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Taste Bud-Derived BDNF Is Required to Maintain Normal Amounts of Innervation to Adult Taste Buds
Lingbin Meng, Lisa Ohman-Gault, Liqun Ma, Robin F. Krimm
eNeuro 22 December 2015, 2 (6) ENEURO.0097-15.2015; DOI: 10.1523/ENEURO.0097-15.2015
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Keywords

  • BDNF
  • geniculate ganglion
  • neurotrophins
  • plasticity
  • taste
  • taste bud

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