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Research ArticleNew Research, Disorders of the Nervous System

Rapid, Coordinate Inflammatory Responses after Experimental Febrile Status Epilepticus: Implications for Epileptogenesis

Katelin P. Patterson, Gary P. Brennan, Megan Curran, Eli Kinney-Lang, Celine Dubé, Faisal Rashid, Catherine Ly, Andre Obenaus and Tallie Z. Baram
eNeuro 8 October 2015, 2 (5) ENEURO.0034-15.2015; https://doi.org/10.1523/ENEURO.0034-15.2015
Katelin P. Patterson
1Department of Anatomy/Neurobiology, University of California-Irvine, Irvine, California 92697
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Gary P. Brennan
2Department of Pediatrics, University of California-Irvine, Irvine, California 92697
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  • ORCID record for Gary P. Brennan
Megan Curran
1Department of Anatomy/Neurobiology, University of California-Irvine, Irvine, California 92697
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Eli Kinney-Lang
2Department of Pediatrics, University of California-Irvine, Irvine, California 92697
4Department of Radiation Medicine and Department of Pediatrics, Loma Linda University School of Medicine, Loma Linda, California 92350
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Celine Dubé
2Department of Pediatrics, University of California-Irvine, Irvine, California 92697
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Faisal Rashid
4Department of Radiation Medicine and Department of Pediatrics, Loma Linda University School of Medicine, Loma Linda, California 92350
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Catherine Ly
1Department of Anatomy/Neurobiology, University of California-Irvine, Irvine, California 92697
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Andre Obenaus
4Department of Radiation Medicine and Department of Pediatrics, Loma Linda University School of Medicine, Loma Linda, California 92350
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Tallie Z. Baram
1Department of Anatomy/Neurobiology, University of California-Irvine, Irvine, California 92697
2Department of Pediatrics, University of California-Irvine, Irvine, California 92697
3Department of Neurology, University of California-Irvine, Irvine, California 92697
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0034-15.2015
PubMed 
26730400
Published By 
Society for Neuroscience
History 
  • Received April 15, 2015
  • Revision received September 25, 2015
  • Accepted September 28, 2015
  • Published online October 8, 2015.
Copyright & Usage 
Copyright © 2015 Patterson et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Katelin P. Patterson1,
  2. Gary P. Brennan2,
  3. Megan Curran1,
  4. Eli Kinney-Lang2,4,
  5. Celine Dubé2,
  6. Faisal Rashid4,
  7. Catherine Ly1,
  8. Andre Obenaus4 and
  9. Tallie Z. Baram1,2,3
  1. 1Department of Anatomy/Neurobiology, University of California-Irvine, Irvine, California 92697
  2. 2Department of Pediatrics, University of California-Irvine, Irvine, California 92697
  3. 3Department of Neurology, University of California-Irvine, Irvine, California 92697
  4. 4Department of Radiation Medicine and Department of Pediatrics, Loma Linda University School of Medicine, Loma Linda, California 92350
  1. Correspondence should be addressed to Tallie Z. Baram, Department of Anatomy/Neurobiology, University of California-Irvine, Irvine, CA 92697. E-mail: tallie{at}uci.edu.
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Author contributions

  1. Author Contributions: K.P.P. and T.Z.B. designed research; K.P.P., G.P.B., M.C., E.K.-L., C.B., F.R., C.L., and A.O. performed research; K.P.P., G.P.B., M.C., E.K.-L., F.R., A.O., and T.Z.B. analyzed data; K.P.P. and T.Z.B. wrote the paper.

Disclosures

  • Authors declare no competing financial interests.

  • This work was supported by National Institutes of Health Grants R37/RO1-NS-35439, T32-NS-45540, P20NS080185, and R01-NS-78279, and an American Epilepsy Society/Epilepsy Foundation of America Predoctoral Fellowship to K.P.P.

Funding

  • HHS | NIH | National Institute of Neurological Disorders and Stroke

    NS35437
  • HHS NIH National Institute of Neurological Disorders and Stroke

    T32 NS045540
  • HHS National institute of Neurological disorders and Stroke

    NS78279

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  • You are viewing the most recent version of this article.
  • previous version (October 08, 2015).

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Rapid, Coordinate Inflammatory Responses after Experimental Febrile Status Epilepticus: Implications for Epileptogenesis
Katelin P. Patterson, Gary P. Brennan, Megan Curran, Eli Kinney-Lang, Celine Dubé, Faisal Rashid, Catherine Ly, Andre Obenaus, Tallie Z. Baram
eNeuro 8 October 2015, 2 (5) ENEURO.0034-15.2015; DOI: 10.1523/ENEURO.0034-15.2015

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Rapid, Coordinate Inflammatory Responses after Experimental Febrile Status Epilepticus: Implications for Epileptogenesis
Katelin P. Patterson, Gary P. Brennan, Megan Curran, Eli Kinney-Lang, Celine Dubé, Faisal Rashid, Catherine Ly, Andre Obenaus, Tallie Z. Baram
eNeuro 8 October 2015, 2 (5) ENEURO.0034-15.2015; DOI: 10.1523/ENEURO.0034-15.2015
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Keywords

  • biomarker
  • cytokine
  • epilepsy
  • febrile seizures
  • heterogeneity
  • magnetic resonance imaging

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