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Research ArticleNew Research, Disorders of the Nervous System

Large-Scale Phenotype-Based Antiepileptic Drug Screening in a Zebrafish Model of Dravet Syndrome

Matthew T. Dinday and Scott C. Baraban
eNeuro 20 August 2015, 2 (4) ENEURO.0068-15.2015; DOI: https://doi.org/10.1523/ENEURO.0068-15.2015
Matthew T. Dinday
1Department of Neurological Surgery, Epilepsy Research Laboratory, University of California San Francisco, San Francisco, California 94143
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Scott C. Baraban
1Department of Neurological Surgery, Epilepsy Research Laboratory, University of California San Francisco, San Francisco, California 94143
2Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, California 94143
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0068-15.2015
PubMed 
26465006
Published By 
Society for Neuroscience
History 
  • Received June 18, 2015
  • Revision received July 28, 2015
  • Accepted August 4, 2015
  • Published online August 20, 2015.
Copyright & Usage 
Copyright © 2015 Dinday and Baraban This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Matthew T. Dinday1 and
  2. Scott C. Baraban1,2
  1. 1Department of Neurological Surgery, Epilepsy Research Laboratory, University of California San Francisco, San Francisco, California 94143
  2. 2Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, California 94143
  1. Correspondence should be addressed to Scott C. Baraban, Department of Neurological Surgery, Epilepsy Research Laboratory, University of California, San Francisco, San Francisco, CA 94143. E-mail: scott.baraban{at}ucsf.edu.
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Author contributions

  1. ↵2 Author contributions: M.T.D. and S.C.B. designed research; M.T.D. and S.C.B. performed research; M.T.D. and S.C.B. analyzed data; S.C.B. wrote the paper.

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Disclosures

  • ↵1 The authors declare no competing financial interests.

  • ↵3 Funding was provided by National Institutes of Health-National Institute of Neurological Disorders and Stroke EUREKA Grant 5R01-NS-079214 and The Joseph & Vera Long Foundation to (S.C.B.).

Funding

  • NIH

    5R01NS079214
  • Joseph & Vera Long Foundation

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  • You are viewing the most recent version of this article.
  • previous version (August 20, 2015).

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Jun 201603617
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July/August 2015
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Large-Scale Phenotype-Based Antiepileptic Drug Screening in a Zebrafish Model of Dravet Syndrome
Matthew T. Dinday, Scott C. Baraban
eNeuro 20 August 2015, 2 (4) ENEURO.0068-15.2015; DOI: 10.1523/ENEURO.0068-15.2015

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Large-Scale Phenotype-Based Antiepileptic Drug Screening in a Zebrafish Model of Dravet Syndrome
Matthew T. Dinday, Scott C. Baraban
eNeuro 20 August 2015, 2 (4) ENEURO.0068-15.2015; DOI: 10.1523/ENEURO.0068-15.2015
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Keywords

  • antiepileptic
  • drug discovery
  • epilepsy
  • high throughput
  • pharmacology
  • zebrafish

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