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Research ArticleNew Research, Disorders of the Nervous System

Age-Related Changes in the Circadian System Unmasked by Constant Conditions

Takahiro J. Nakamura, Wataru Nakamura, Isao T. Tokuda, Takahiro Ishikawa, Takashi Kudo, Christopher S. Colwell and Gene D. Block
eNeuro 27 August 2015, 2 (4) ENEURO.0064-15.2015; https://doi.org/10.1523/ENEURO.0064-15.2015
Takahiro J. Nakamura
1Department of Life Sciences, School of Agriculture, Meiji University, Kanagawa, Kawasaki 214-8571, Japan
2Faculty of Pharmaceutical Sciences, Teikyo Heisei University, Tokyo 164-8530, Japan
3Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, California 90024-1759
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  • ORCID record for Takahiro J. Nakamura
Wataru Nakamura
4Laboratory of Oral Chronobiology, Graduate School of Dentistry, Osaka University, Suita, Osaka 565-0871, Japan
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Isao T. Tokuda
5Department of Mechanical Engineering, Ritsumeikan University, Shiga, Kusatsu 525-8577, Japan
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Takahiro Ishikawa
2Faculty of Pharmaceutical Sciences, Teikyo Heisei University, Tokyo 164-8530, Japan
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Takashi Kudo
3Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, California 90024-1759
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Christopher S. Colwell
3Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, California 90024-1759
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Gene D. Block
3Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, California 90024-1759
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0064-15.2015
PubMed 
26464996
Published By 
Society for Neuroscience
History 
  • Received June 1, 2015
  • Revision received August 17, 2015
  • Accepted August 22, 2015
  • Published online August 27, 2015.
Copyright & Usage 
Copyright © 2015 Nakamura et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Takahiro J. Nakamura1,2,3,
  2. Wataru Nakamura4,
  3. Isao T. Tokuda5,
  4. Takahiro Ishikawa2,
  5. Takashi Kudo3,
  6. Christopher S. Colwell3 and
  7. Gene D. Block3
  1. 1Department of Life Sciences, School of Agriculture, Meiji University, Kanagawa, Kawasaki 214-8571, Japan
  2. 2Faculty of Pharmaceutical Sciences, Teikyo Heisei University, Tokyo 164-8530, Japan
  3. 3Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, California 90024-1759
  4. 4Laboratory of Oral Chronobiology, Graduate School of Dentistry, Osaka University, Suita, Osaka 565-0871, Japan
  5. 5Department of Mechanical Engineering, Ritsumeikan University, Shiga, Kusatsu 525-8577, Japan
  1. Correspondence should be addressed to either of the following: Takahiro J. Nakamura, Department of Life Sciences, School of Agriculture, Meiji University, 1-1-1 Higashimita, Taka-ku, Kanagawa, Kawasaki 214-8571, E-mail: takahiro{at}meiji.ac.jp; or Wataru Nakamura, Laboratory of Oral Chronobiology, Graduate School of Dentistry, Osaka University, 1-8 Yamadaoka, Suita, Osaka 565-0871, Japan, E-mail: wataru{at}dent.osaka-u.ac.jp.
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Author contributions

  1. ↵2 Author contributions: T.J.N., W.N., C.S.C., and G.D.B. designed research; T.J.N. and T.K. performed research; T.J.N., W.N., I.T.T., and T.I. analyzed data; T.J.N., W.N., I.T.T., T.K., C.S.C., and G.D.B. wrote the paper..

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Disclosures

  • ↵1 The authors declare no competing financial interests.

  • ↵3 This work was supported by JSPS KAKENHI Grants 24790238 (T.J.N.), 26860160 (T.J.N.), and 26462809 (W.N.).

Funding

  • JSPS KAKENHI

    24790238
  • JSPS KAKENHI

    26860160
  • JSPS KAKENHI

    26462809

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  • You are viewing the most recent version of this article.
  • previous version (August 27, 2015).

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Age-Related Changes in the Circadian System Unmasked by Constant Conditions
Takahiro J. Nakamura, Wataru Nakamura, Isao T. Tokuda, Takahiro Ishikawa, Takashi Kudo, Christopher S. Colwell, Gene D. Block
eNeuro 27 August 2015, 2 (4) ENEURO.0064-15.2015; DOI: 10.1523/ENEURO.0064-15.2015

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Age-Related Changes in the Circadian System Unmasked by Constant Conditions
Takahiro J. Nakamura, Wataru Nakamura, Isao T. Tokuda, Takahiro Ishikawa, Takashi Kudo, Christopher S. Colwell, Gene D. Block
eNeuro 27 August 2015, 2 (4) ENEURO.0064-15.2015; DOI: 10.1523/ENEURO.0064-15.2015
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Keywords

  • aging
  • imaging
  • PER2::luciferase
  • Suprachiasmatic Nucleus

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