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Research ArticleNew Research, Neuronal Excitability

Metaplastic Regulation of CA1 Schaffer Collateral Pathway Plasticity by Hebbian MGluR1a-Mediated Plasticity at Excitatory Synapses onto Somatostatin-Expressing Interneurons

Cristina Vasuta, Julien Artinian, Isabel Laplante, Sarah Hébert-Seropian, Karim Elayoubi and Jean-Claude Lacaille
eNeuro 12 August 2015, 2 (4) ENEURO.0051-15.2015; https://doi.org/10.1523/ENEURO.0051-15.2015
Cristina Vasuta
Groupe de Recherche sur le Système Nerveux Central and Department of Neuroscience, Faculty of Medicine, Université de Montréal, Montreal, Quebec H3T 1J4, Canada
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Julien Artinian
Groupe de Recherche sur le Système Nerveux Central and Department of Neuroscience, Faculty of Medicine, Université de Montréal, Montreal, Quebec H3T 1J4, Canada
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  • ORCID record for Julien Artinian
Isabel Laplante
Groupe de Recherche sur le Système Nerveux Central and Department of Neuroscience, Faculty of Medicine, Université de Montréal, Montreal, Quebec H3T 1J4, Canada
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Sarah Hébert-Seropian
Groupe de Recherche sur le Système Nerveux Central and Department of Neuroscience, Faculty of Medicine, Université de Montréal, Montreal, Quebec H3T 1J4, Canada
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Karim Elayoubi
Groupe de Recherche sur le Système Nerveux Central and Department of Neuroscience, Faculty of Medicine, Université de Montréal, Montreal, Quebec H3T 1J4, Canada
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Jean-Claude Lacaille
Groupe de Recherche sur le Système Nerveux Central and Department of Neuroscience, Faculty of Medicine, Université de Montréal, Montreal, Quebec H3T 1J4, Canada
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0051-15.2015
PubMed 
26464997
Published By 
Society for Neuroscience
History 
  • Received May 11, 2015
  • Revision received July 22, 2015
  • Accepted August 6, 2015
  • Published online August 12, 2015.
Copyright & Usage 
Copyright © 2015 Vasuta et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Cristina Vasuta,
  2. Julien Artinian,
  3. Isabel Laplante,
  4. Sarah Hébert-Seropian,
  5. Karim Elayoubi and
  6. Jean-Claude Lacaille
  1. Groupe de Recherche sur le Système Nerveux Central and Department of Neuroscience, Faculty of Medicine, Université de Montréal, Montreal, Quebec H3T 1J4, Canada
  1. Correspondence should be addressed to Dr Jean-Claude Lacaille, Département de Neurosciences, Faculté de Médecine, Université de Montréal, Case Postale 6128, Succursale Centre-Ville, Montréal, QC H3C 3J7, Canada. E-mail: jean-claude.lacaille{at}umontreal.ca.
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Author contributions

  1. ↵2 Author contributions: C.V., J.A., and J.-C.L. designed research; C.V., J.A., I.L., S.H.-S., and K.E. performed research and analyzed data; C.V., J.A., I.L., and J.-C.L. wrote the paper.

View Abstract

Disclosures

  • ↵1 The authors declare no competing financial interests.

  • ↵3 This work was supported by the Canadian Institutes of Health Research (operating grant to J.-C.L.; MOP-10848), the Fonds de la Recherche du Québec en Santé [FRQS Group grant to J.-C.L.; Groupe de Recherche sur le Système Nerveux Central (GRSNC)]. J.-C.L. is the recipient of the Canada Research Chair in Cellular and Molecular Neurophysiology. C.V. and J.A. were supported by a GRSNC Fellowship, and S.H.-S. by a Studentship from CIHR.

Funding

  • Canadian Institutes of Health Research

    MOP-10848
  • Fonds de Recherche du Québec - Santé (Fonds de la recherche en sante du Quebec)

    501100000156; GRSNC; 5249
  • Canada Research Chair Program

    950-213424

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  • You are viewing the most recent version of this article.
  • previous version (August 12, 2015).

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Jun 201602811
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Total63670431877
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Metaplastic Regulation of CA1 Schaffer Collateral Pathway Plasticity by Hebbian MGluR1a-Mediated Plasticity at Excitatory Synapses onto Somatostatin-Expressing Interneurons
Cristina Vasuta, Julien Artinian, Isabel Laplante, Sarah Hébert-Seropian, Karim Elayoubi, Jean-Claude Lacaille
eNeuro 12 August 2015, 2 (4) ENEURO.0051-15.2015; DOI: 10.1523/ENEURO.0051-15.2015

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Metaplastic Regulation of CA1 Schaffer Collateral Pathway Plasticity by Hebbian MGluR1a-Mediated Plasticity at Excitatory Synapses onto Somatostatin-Expressing Interneurons
Cristina Vasuta, Julien Artinian, Isabel Laplante, Sarah Hébert-Seropian, Karim Elayoubi, Jean-Claude Lacaille
eNeuro 12 August 2015, 2 (4) ENEURO.0051-15.2015; DOI: 10.1523/ENEURO.0051-15.2015
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Keywords

  • hippocampus
  • LTP
  • metaplasticity
  • mGluR1a
  • somatostatin-interneuron

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