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Research ArticleNegative Results, Disorders of the Nervous System

Effects of Exercise on Progranulin Levels and Gliosis in Progranulin-Insufficient Mice

Andrew E. Arrant, Aashka R. Patel and Erik D. Roberson
eNeuro 22 June 2015, 2 (3) ENEURO.0061-14.2015; https://doi.org/10.1523/ENEURO.0061-14.2015
Andrew E. Arrant
Departments of Neurology and Neurobiology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, Alabama
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Aashka R. Patel
Departments of Neurology and Neurobiology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, Alabama
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Erik D. Roberson
Departments of Neurology and Neurobiology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, Alabama
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0061-14.2015
Published By 
Society for Neuroscience
History 
  • Received November 24, 2014
  • Revision received June 13, 2015
  • Accepted June 16, 2015
  • Published online June 22, 2015.
Copyright & Usage 
Copyright © 2015 Arrant et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Andrew E. Arrant,
  2. Aashka R. Patel and
  3. Erik D. Roberson
  1. Departments of Neurology and Neurobiology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, Alabama
  1. Correspondence should be addressed to Dr. Erik D. Roberson, University of Alabama at Birmingham, 1825 University Boulevard, Shelby 1106, Birmingham, AL 35294-2182. E-mail: eroberson{at}uab.edu.
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Author contributions

  1. ↵2 Author Contributions: A.E.A. and E.D.R. designed research; A.E.A. and A.R.P. performed research; A.E.A. and E.D.R. analyzed data; A.E.A. and E.D.R. wrote the paper.

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Disclosures

  • ↵1 The authors report no conflict of interest.

  • ↵3 This work was supported by the Consortium for Frontotemporal Dementia Research and the National Institutes of Health (T32HD071866, P30NS47466, R01NS075487). We thank James Black and Miriam Roberson for help with the mouse colony.

Funding

  • Consortium for Frontotemporal Dementia Research

  • HHS | NIH | National Institute of Child Health and Human Development

    T32HD071866
  • National Institute of Neurological Disorders and Stroke

    P30NS47466
  • National Institute of Neurological Disorders and Stroke

    R01NS075487

Other Version

  • You are viewing the most recent version of this article.
  • previous version (June 22, 2015).

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Jun 20160175
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Effects of Exercise on Progranulin Levels and Gliosis in Progranulin-Insufficient Mice
Andrew E. Arrant, Aashka R. Patel, Erik D. Roberson
eNeuro 22 June 2015, 2 (3) ENEURO.0061-14.2015; DOI: 10.1523/ENEURO.0061-14.2015

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Effects of Exercise on Progranulin Levels and Gliosis in Progranulin-Insufficient Mice
Andrew E. Arrant, Aashka R. Patel, Erik D. Roberson
eNeuro 22 June 2015, 2 (3) ENEURO.0061-14.2015; DOI: 10.1523/ENEURO.0061-14.2015
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Keywords

  • BDNF
  • exercise
  • Frontotemporal Dementia
  • Progranulin

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