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Research ArticleTheory/New Concepts, Disorders of the Nervous System

Genetic Variations in the Serotonergic System Mediate a Combined, Weakened Response to SSRI Treatment: A Proposed Model

Adam Pettitt
eNeuro 26 May 2015, 2 (3) ENEURO.0032-14.2015; https://doi.org/10.1523/ENEURO.0032-14.2015
Adam Pettitt
1Department of Psychology, University of Oregon, Eugene, Oregon 97403
2Department of Biology, Western Oregon University, Monmouth, Oregon 97361
3Department of Psychology, Western Oregon University, Monmouth, Oregon 97361
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0032-14.2015
PubMed 
26464988
Published By 
Society for Neuroscience
History 
  • Received September 27, 2014
  • Revision received May 1, 2015
  • Accepted May 6, 2015
  • Published online May 26, 2015.
Copyright & Usage 
Copyright © 2015 Pettitt This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Adam Pettitt1,2,3
  1. 1Department of Psychology, University of Oregon, Eugene, Oregon 97403
  2. 2Department of Biology, Western Oregon University, Monmouth, Oregon 97361
  3. 3Department of Psychology, Western Oregon University, Monmouth, Oregon 97361
  1. Correspondence should be addressed to: Adam Pettitt, Western Oregon University, APSC 301, 345 Monmouth Avenue, Monmouth, OR 97361. E-mail: pettitta{at}wou.edu.
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Author contributions

  1. ↵2 Author Contributions: A.P. performed research; A.P. wrote the paper.

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Disclosures

  • ↵1 The author declares no competing financial interests.

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eneuro: 2 (3)
eNeuro
Vol. 2, Issue 3
May/June 2015
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Genetic Variations in the Serotonergic System Mediate a Combined, Weakened Response to SSRI Treatment: A Proposed Model
Adam Pettitt
eNeuro 26 May 2015, 2 (3) ENEURO.0032-14.2015; DOI: 10.1523/ENEURO.0032-14.2015

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Genetic Variations in the Serotonergic System Mediate a Combined, Weakened Response to SSRI Treatment: A Proposed Model
Adam Pettitt
eNeuro 26 May 2015, 2 (3) ENEURO.0032-14.2015; DOI: 10.1523/ENEURO.0032-14.2015
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  • Article
    • Abstract
    • Significance Statement
    • Introduction
    • Serotonin transporter protein
    • 5-HT1A
    • 5-HT1A and 5-HTTLPR combined effect
    • Discussion
    • Acknowledgments
    • Footnotes
    • References
    • Synthesis
  • Figures & Data
  • Info & Metrics
  • eLetters
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Keywords

  • 5-HT1A
  • 5-HTTLPR
  • depression
  • Psychopharmacology
  • serotonin
  • SSRI

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