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Research ArticleNew Research, Neuronal Excitability

Leptin Induces a Novel Form of NMDA Receptor-Dependent LTP at Hippocampal Temporoammonic-CA1 Synapses

Xiao Luo, Gemma McGregor, Andrew J. Irving and Jenni Harvey
eNeuro 26 May 2015, 2 (3) ENEURO.0007-15.2015; https://doi.org/10.1523/ENEURO.0007-15.2015
Xiao Luo
Division of Neuroscience, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom
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  • ORCID record for Xiao Luo
Gemma McGregor
Division of Neuroscience, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom
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Andrew J. Irving
Division of Neuroscience, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom
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Jenni Harvey
Division of Neuroscience, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0007-15.2015
PubMed 
26464986
Published By 
Society for Neuroscience
History 
  • Received January 27, 2015
  • Revision received May 12, 2015
  • Accepted May 15, 2015
  • Published online May 26, 2015.
Copyright & Usage 
Copyright © 2015 Luo et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Xiao Luo,
  2. Gemma McGregor,
  3. Andrew J. Irving and
  4. Jenni Harvey
  1. Division of Neuroscience, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, United Kingdom
  1. Correspondence should be addressed to Dr. Jenni Harvey, Division of Neuroscience, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK. E-mail: j.z.harvey{at}dundee.ac.uk.
  • X. Luo’s present address: Axe de Neurosciences cellulaires et moléculaires, Centre de Recherche, Université Laval Robert-Giffard, Département de biochimie, de microbiologie et de bio-informatique, Faculté des Sciences et de Génie, Université Laval, 2601 Chemin de la Canardière, Québec G1J 2G3, Canada.

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Author contributions

  1. ↵2 Author Contributions: X.L. and G.M. performed research; X.L. and G.M. analyzed data; A.J.I. and J.H. designed research; A.J.I. and J.H. wrote the paper.

  • X. Luo’s present address: Axe de Neurosciences cellulaires et moléculaires, Centre de Recherche, Université Laval Robert-Giffard, Département de biochimie, de microbiologie et de bio-informatique, Faculté des Sciences et de Génie, Université Laval, 2601 Chemin de la Canardière, Québec G1J 2G3, Canada.

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Disclosures

  • ↵1 The authors declare no competing financial interests.

  • ↵3 J.H. is funded by The Cunningham Trust.

Funding

  • The Cunningham Trust

    ACC/KWF/CT12/10

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Total 2025131862357
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Total 20263130839
Total57275001677
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eneuro: 2 (3)
eNeuro
Vol. 2, Issue 3
May/June 2015
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Leptin Induces a Novel Form of NMDA Receptor-Dependent LTP at Hippocampal Temporoammonic-CA1 Synapses
Xiao Luo, Gemma McGregor, Andrew J. Irving, Jenni Harvey
eNeuro 26 May 2015, 2 (3) ENEURO.0007-15.2015; DOI: 10.1523/ENEURO.0007-15.2015

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Leptin Induces a Novel Form of NMDA Receptor-Dependent LTP at Hippocampal Temporoammonic-CA1 Synapses
Xiao Luo, Gemma McGregor, Andrew J. Irving, Jenni Harvey
eNeuro 26 May 2015, 2 (3) ENEURO.0007-15.2015; DOI: 10.1523/ENEURO.0007-15.2015
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Keywords

  • excitatory synaptic transmission
  • leptin
  • NMDA receptor
  • synaptic plasticity

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