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Research ArticleNew Research, Sensory and Motor Systems

Sigh and Eupnea Rhythmogenesis Involve Distinct Interconnected Subpopulations: A Combined Computational and Experimental Study

Natalia Toporikova, Marc Chevalier and Muriel Thoby-Brisson
eNeuro 7 April 2015, 2 (2) ENEURO.0074-14.2015; DOI: https://doi.org/10.1523/ENEURO.0074-14.2015
Natalia Toporikova
1Department of Biology, Washington and Lee University, Lexington, Virginia 24450
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Marc Chevalier
2Institut de Neurosciences Cognitives et Intégratives d’Aquitaine, CNRS UMR 5287, Université de Bordeaux, 33076 Bordeaux, France
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Muriel Thoby-Brisson
2Institut de Neurosciences Cognitives et Intégratives d’Aquitaine, CNRS UMR 5287, Université de Bordeaux, 33076 Bordeaux, France
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0074-14.2015
PubMed 
26464980
Published By 
Society for Neuroscience
History 
  • Received December 22, 2014
  • Revision received April 1, 2015
  • Accepted April 2, 2015
  • Published online April 7, 2015.
Copyright & Usage 
Copyright © 2015 Toporikova et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Natalia Toporikova1,
  2. Marc Chevalier2 and
  3. Muriel Thoby-Brisson2
  1. 1Department of Biology, Washington and Lee University, Lexington, Virginia 24450
  2. 2Institut de Neurosciences Cognitives et Intégratives d’Aquitaine, CNRS UMR 5287, Université de Bordeaux, 33076 Bordeaux, France
  1. Correspondence should be addressed to either Dr. Muriel Thoby-Brisson, Institut de Neurosciences Cognitives et Intégratives d’Aquitaine, CNRS UMR 5287, Université de Bordeaux, 146 rue Léo Saignat, 33076 Bordeaux, France, E-mail: muriel.thoby-brisson{at}u-bordeaux.fr; or Dr. Natalia Toporikova, Department of Biology and Neuroscience Program, Washington and Lee University, Lexington, VA 24450, E-mail: toporikovan{at}wlu.edu.
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Author contributions

  1. ↵2 Author Contributions: N.T. and M.T-B. designed research; N.T., M.C. and M.T-B. performed research; N.T. and M.T-B. analyzed data; N.T. and M.T-B. wrote the paper.

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Disclosures

  • ↵1 The authors report no financial conflicts of interest.

  • ↵3 This work was supported by the Institut National de la Santé et de la Recherche Médicale and the Agence Nationale de la Recherche (ANR12-BSV4-0011-01) (both to M.T.-B.).

Funding

  • ANR

    ANR12-BSV4-0011-01

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March/April 2015
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Sigh and Eupnea Rhythmogenesis Involve Distinct Interconnected Subpopulations: A Combined Computational and Experimental Study
Natalia Toporikova, Marc Chevalier, Muriel Thoby-Brisson
eNeuro 7 April 2015, 2 (2) ENEURO.0074-14.2015; DOI: 10.1523/ENEURO.0074-14.2015

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Sigh and Eupnea Rhythmogenesis Involve Distinct Interconnected Subpopulations: A Combined Computational and Experimental Study
Natalia Toporikova, Marc Chevalier, Muriel Thoby-Brisson
eNeuro 7 April 2015, 2 (2) ENEURO.0074-14.2015; DOI: 10.1523/ENEURO.0074-14.2015
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Keywords

  • computational model
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  • pre-Bötzinger complex
  • respiratory network
  • sigh generation

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