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Research ArticleNew Research, Neuronal Excitability

Presynaptic NR2A-Containing NMDARs Are Required for LTD between the Amygdala and the Perirhinal Cortex: A Potential Mechanism for the Emotional Modulation of Memory?

Michael D. Laing and Zafar I. Bashir
eNeuro 25 February 2015, 2 (1) ENEURO.0046-14.2015; DOI: https://doi.org/10.1523/ENEURO.0046-14.2015
Michael D. Laing
1Neuroscience and Mental Health Research Institute, Hadyn Ellis Building, Cathays, Cardiff, CF24 4HQ, United Kingdom
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Zafar I. Bashir
2School of Physiology and Pharmacology, Bristol University, Bristol, BS8 1TD, United Kingdom
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0046-14.2015
PubMed 
26464970
Published By 
Society for Neuroscience
History 
  • Received October 23, 2014
  • Revision received February 10, 2015
  • Accepted February 23, 2015
  • Published online February 25, 2015.
Copyright & Usage 
Copyright © 2015 Laing and Bashir This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Michael D. Laing1 and
  2. Zafar I. Bashir2
  1. 1Neuroscience and Mental Health Research Institute, Hadyn Ellis Building, Cathays, Cardiff, CF24 4HQ, United Kingdom
  2. 2School of Physiology and Pharmacology, Bristol University, Bristol, BS8 1TD, United Kingdom
  1. Correspondence should be addressed to Michael Laing, Neuroscience and Mental Health Research Institute, Hadyn Ellis Building, Maindy Road, Cardiff University, Cardiff, CF24 4HQ. E-mail: LaingM{at}cardiff.ac.uk
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Author contributions

  1. ↵2 Author Contributions: M.D.L. and Z.I.B. designed research; M.D.L. performed research; M.D.L. analyzed data; M.D.L. wrote the paper.

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Disclosures

  • ↵1 Authors report no conflict of interest.

  • ↵3 We thank the Medical Research Council for their financial support. In addition, we thank Vincenzo Crunelli for his comments on the manuscript.

Funding

  • medical research council (MRC)

    G0900177

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eneuro: 2 (1)
eNeuro
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January/February 2015
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Presynaptic NR2A-Containing NMDARs Are Required for LTD between the Amygdala and the Perirhinal Cortex: A Potential Mechanism for the Emotional Modulation of Memory?
Michael D. Laing, Zafar I. Bashir
eNeuro 25 February 2015, 2 (1) ENEURO.0046-14.2015; DOI: 10.1523/ENEURO.0046-14.2015

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Presynaptic NR2A-Containing NMDARs Are Required for LTD between the Amygdala and the Perirhinal Cortex: A Potential Mechanism for the Emotional Modulation of Memory?
Michael D. Laing, Zafar I. Bashir
eNeuro 25 February 2015, 2 (1) ENEURO.0046-14.2015; DOI: 10.1523/ENEURO.0046-14.2015
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Keywords

  • amygdala
  • emotion
  • Memory
  • perirhinal
  • Plasticity
  • transmission

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