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Research ArticleOpen Source Tools and Methods, Novel Tools and Methods

DeepEthoProfile—Rapid Behavior Recognition in Long-Term Recorded Home-Cage Mice

Andrei Istudor, Alexej Schatz and York Winter
eNeuro 15 July 2025, 12 (7) ENEURO.0369-24.2025; https://doi.org/10.1523/ENEURO.0369-24.2025
Andrei Istudor
Humboldt-Universität zu Berlin, Berlin 10099, Germany
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Alexej Schatz
Humboldt-Universität zu Berlin, Berlin 10099, Germany
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York Winter
Humboldt-Universität zu Berlin, Berlin 10099, Germany
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0369-24.2025
PubMed 
40664508
Published By 
Society for Neuroscience
History 
  • Received August 23, 2024
  • Revision received April 2, 2025
  • Accepted April 10, 2025
  • Published online July 15, 2025.
Copyright & Usage 
Copyright © 2025 Istudor et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Andrei Istudor,
  2. Alexej Schatz and
  3. York Winter
  1. Humboldt-Universität zu Berlin, Berlin 10099, Germany
  1. Correspondence should be addressed to Andrei Istudor at andrei.istudor{at}gmail.com or York Winter at york.winter{at}hu-berlin.de.
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Author contributions

  1. Author contributions: A.I., A.S., and Y.W. designed research; A.I. performed research; A.I. contributed unpublished reagents/analytic tools; A.I. analyzed data; A.I., A.S., and Y.W. wrote the paper.

Disclosures

  • This work was supported by the BMBF program “Alternative methods for animal experiments” FKZ 031A418 and FKZ 161L0228, as well as by the DFG Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) through SFB 1315, project-ID 327654276, and EXC 257 NeuroCure, project-ID 441 39052203. We thank Prisila Charles, Rebecca Saager, and Cedric Rauch for their dedicated efforts in working with the animals and carrying out the manual annotations; Rupert Overall and Janine Musolf for their thorough evaluation of a pre-release version of our software, which involved data from multiple sets of 20 mice across two EthoProfiler racks operated concurrently; Peter Spende, Francesco Bagorda, and Katja Frei for their significant contributions in the development of the acquisition hardware; and Clemens Winter and Rupert Overall for proof-reading and providing feed-back to the initial version of the manuscript. The article processing charge was funded by the Open Access Publication Fund of Humboldt-Universität zu Berlin.

  • PhenoSys GmbH, which manufactures and distributes the 10-cage EthoProfiler data acquisition system, counts Y.W. among its equity owners.

Funding

  • Bundesministerium für Bildung und Forschung (BMBF)

    FKZ 031A418
  • Deutsche Forschungsgemeinschaft (DFG)

    SFB 1315

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July 2025
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DeepEthoProfile—Rapid Behavior Recognition in Long-Term Recorded Home-Cage Mice
Andrei Istudor, Alexej Schatz, York Winter
eNeuro 15 July 2025, 12 (7) ENEURO.0369-24.2025; DOI: 10.1523/ENEURO.0369-24.2025

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DeepEthoProfile—Rapid Behavior Recognition in Long-Term Recorded Home-Cage Mice
Andrei Istudor, Alexej Schatz, York Winter
eNeuro 15 July 2025, 12 (7) ENEURO.0369-24.2025; DOI: 10.1523/ENEURO.0369-24.2025
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