Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT

User menu

Search

  • Advanced search
eNeuro
eNeuro

Advanced Search

 

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT
PreviousNext
Research ArticleResearch Article: New Research, Disorders of the Nervous System

Loss of Neuronal Imp Contributes to Seizure Behavior through Syndecan Function

Paula R. Roy and Nichole Link
eNeuro 21 April 2025, 12 (5) ENEURO.0545-24.2025; https://doi.org/10.1523/ENEURO.0545-24.2025
Paula R. Roy
Department of Neurobiology, University of Utah, Salt Lake City, Utah 84112
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Paula R. Roy
Nichole Link
Department of Neurobiology, University of Utah, Salt Lake City, Utah 84112
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/ENEURO.0545-24.2025
PubMed 
40258646
Published By 
Society for Neuroscience
History 
  • Received November 26, 2024
  • Revision received March 27, 2025
  • Accepted March 28, 2025
  • Published online April 21, 2025.
Copyright & Usage 
Copyright © 2025 Roy and Link This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Paula R. Roy and
  2. Nichole Link
  1. Department of Neurobiology, University of Utah, Salt Lake City, Utah 84112
  1. Correspondence should be addressed to Nichole Link at nichole.link{at}neuro.utah.edu.
View Full Text

Author contributions

  1. Author contributions: P.R.R. and N.L. designed research; P.R.R. and N.L. performed research; P.R.R. and N.L. analyzed data; P.R.R. and N.L. wrote the paper.

Disclosures

  • The authors declare no competing financial interest.

  • We thank the members of the Link lab for critical reading of the manuscript. We thank Claude Desplan for providing the anti-Imp antibody used in this study. The monoclonal antibody Elav-9F8A9, developed by Gerald M. Rubin at Janelia Farm Research, Howard Hughes Medical Institute, was obtained from the Developmental Studies Hybridoma Bank, created by the NICHD of the NIH and maintained at the Department of Biology, University of Iowa, Iowa City, IA 52242. We acknowledge the information provided by FlyBase (National Human Genome Research Institute Awards U41HG000739 and U24HG010859) using release FB2023_04. Stocks obtained from the Bloomington Drosophila Stock Center (NIH P40OD018537) were used in this study. P.R.R. was supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health under Award Number T32HD007491 and the National Institutes of Health under Ruth L. Kirschstein National Research Service Award T32HG008962 from the National Human Genome Research Institute at the University of Utah. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. N.L. was funded in part by the National Institute of Allergy and Infectious Diseases Grants R56AI170857 and R01AI170857 and the University of Utah.

Funding

  • HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

    T32HD007491
  • HHS | NIH | National Human Genome Research Institute (NHGRI)

    T32HG008962
  • HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID)

    R56AI170857; R01AI170857

Other Version

  • You are viewing the most recent version of this article.
  • previous version (April 21, 2025).
  • previous version (April 21, 2025).

Online Impact

 

Article usage

Select a custom date range for the past year
E.g., 2025-06-12
to
E.g., 2025-06-12

Article usage: April 2025 to June 2025

AbstractFullPdf
Apr 20252700126
May 2025124371172
Jun 2025156821
Total 2025409439319
Total409439319
Back to top

In this issue

eneuro: 12 (5)
eNeuro
Vol. 12, Issue 5
May 2025
  • Table of Contents
  • Index by author
  • Masthead (PDF)
Email

Thank you for sharing this eNeuro article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Loss of Neuronal Imp Contributes to Seizure Behavior through Syndecan Function
(Your Name) has forwarded a page to you from eNeuro
(Your Name) thought you would be interested in this article in eNeuro.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
Loss of Neuronal Imp Contributes to Seizure Behavior through Syndecan Function
Paula R. Roy, Nichole Link
eNeuro 21 April 2025, 12 (5) ENEURO.0545-24.2025; DOI: 10.1523/ENEURO.0545-24.2025

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Share
Loss of Neuronal Imp Contributes to Seizure Behavior through Syndecan Function
Paula R. Roy, Nichole Link
eNeuro 21 April 2025, 12 (5) ENEURO.0545-24.2025; DOI: 10.1523/ENEURO.0545-24.2025
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Significance Statement
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Footnotes
    • References
    • Synthesis
    • Author Response
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • Drosophila
  • neurogenetics
  • RNA-binding proteins
  • seizure

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

Research Article: New Research

  • Release of extracellular matrix components after human traumatic brain injury
  • Action intentions reactivate representations of task-relevant cognitive cues
  • Interference underlies attenuation upon relearning in sensorimotor adaptation
Show more Research Article: New Research

Disorders of the Nervous System

  • Release of extracellular matrix components after human traumatic brain injury
  • Gene variants related to primary familial brain calcification: perspectives from bibliometrics and meta-analysis
  • Expression of HDAC3-Y298H Point Mutant in Medial Habenula Cholinergic Neurons Has No Effect on Cocaine-Induced Behaviors
Show more Disorders of the Nervous System

Subjects

  • Disorders of the Nervous System
  • Home
  • Alerts
  • Follow SFN on BlueSky
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Latest Articles
  • Issue Archive
  • Blog
  • Browse by Topic

Information

  • For Authors
  • For the Media

About

  • About the Journal
  • Editorial Board
  • Privacy Notice
  • Contact
  • Feedback
(eNeuro logo)
(SfN logo)

Copyright © 2025 by the Society for Neuroscience.
eNeuro eISSN: 2373-2822

The ideas and opinions expressed in eNeuro do not necessarily reflect those of SfN or the eNeuro Editorial Board. Publication of an advertisement or other product mention in eNeuro should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in eNeuro.