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History
- Received May 16, 2024
- Revision received March 17, 2025
- Accepted March 20, 2025
- Published online April 17, 2025.
Copyright & Usage
Copyright © 2025 Kushner et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
Author Information
- J. Keenan Kushner1,2,3,
- Paige B. Hoffman1,3,
- Christine R. Brzezinski3,
- Matthew N. Svalina1,2,4,5,
- Brent R. O’Neill1,3,
- Todd C. Hankinson1,3,
- Charles C. Wilkinson1,3,
- Michael H. Handler1,3,
- Serapio M. Baca2,6,
- Molly M. Huntsman1,2,7 and
- Allyson L. Alexander1,3
- 1Neuroscience Graduate Program, University of Colorado | Anschutz Medical Campus, Aurora, Colorado 80045
- 2Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado | Anschutz Medical Campus, Aurora, Colorado 80045
- 3Department of Neurosurgery, School of Medicine, University of Colorado | Anschutz Medical Campus, Aurora, Colorado 80045
- 4Medical Scientist Training Program, University of Colorado | Anschutz Medical Campus, Aurora, Colorado 80045
- 5Department of Cell and Developmental Biology, University of Colorado | Anschutz Medical Campus, Aurora, Colorado 80045
- 6Department of Pharmacology, University of Virginia, Charlottesville, Virginia 22903
- 7Department of Pediatrics, School of Medicine, University of Colorado | Anschutz Medical Campus, Aurora, Colorado 80045
- Correspondence should be addressed to J. Keenan Kushner at Keenan.Kushner{at}cuanschutz.edu or Allyson L. Alexander at Allyson.Alexander{at}childrenscolorado.org.
Author contributions
Author contributions: J.K.K., M.H.H., and A.L.A. designed research; J.K.K., P.B.H., C.R.B., M.N.S., B.R.O., T.C.H., C.C.W., and M.H.H. performed research; S.M.B. contributed unpublished reagents/analytic tools; J.K.K. analyzed data; J.K.K., M.H.H., and A.L.A. wrote the paper.
Disclosures
The authors declare no competing financial interests.
These studies were supported by grants from the National Institutes of Health: R56 MH127213 (M.M.H.), R01NS095311 (M.M.H.), AES Junior Investigator Award (A.L.A.); NINDS Award 1K08NS131572-01A1 (A.L.A.).
Funding
HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)
1K08NS131572-01A1; R01NS095311HHS | NIH | National Institute of Mental Health (NIMH)
MH127213
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