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Research ArticleResearch Article: New Research, Cognition and Behavior

Individual Differences in Cognition and Perception Predict Neural Processing of Speech in Noise for Audiometrically Normal Listeners

Sana Shehabi, Daniel C. Comstock, Kelsey Mankel, Brett M. Bormann, Soukhin Das, Hilary Brodie, Doron Sagiv and Lee M. Miller
eNeuro 18 March 2025, 12 (4) ENEURO.0381-24.2025; https://doi.org/10.1523/ENEURO.0381-24.2025
Sana Shehabi
1Center for Mind and Brain, University of California, Davis, Davis, California 95618
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Daniel C. Comstock
1Center for Mind and Brain, University of California, Davis, Davis, California 95618
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Kelsey Mankel
1Center for Mind and Brain, University of California, Davis, Davis, California 95618
2Institute for Intelligent Systems, University of Memphis, Memphis, Tennessee 38152
3School of Communication Sciences & Disorders, University of Memphis, Memphis, Tennessee 38152
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Brett M. Bormann
1Center for Mind and Brain, University of California, Davis, Davis, California 95618
4Neuroscience Graduate Group, University of California, Davis, Davis, California 95616
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Soukhin Das
1Center for Mind and Brain, University of California, Davis, Davis, California 95618
5Psychology Graduate Group, University of California, Davis, Davis, California 95616
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Hilary Brodie
6Departments of Otolaryngology | Head and Neck Surgery, University of California, Davis, Davis, California 95616
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Doron Sagiv
6Departments of Otolaryngology | Head and Neck Surgery, University of California, Davis, Davis, California 95616
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Lee M. Miller
1Center for Mind and Brain, University of California, Davis, Davis, California 95618
6Departments of Otolaryngology | Head and Neck Surgery, University of California, Davis, Davis, California 95616
7Neurobiology, Physiology and Behavior, University of California, Davis, Davis, California 95616
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0381-24.2025
PubMed 
40101960
Published By 
Society for Neuroscience
History 
  • Received August 29, 2024
  • Revision received January 27, 2025
  • Accepted February 11, 2025
  • Published online March 18, 2025.
Copyright & Usage 
Copyright © 2025 Shehabi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Sana Shehabi1,
  2. Daniel C. Comstock1,
  3. Kelsey Mankel1,2,3,
  4. Brett M. Bormann1,4,
  5. Soukhin Das1,5,
  6. Hilary Brodie6,
  7. Doron Sagiv6 and
  8. Lee M. Miller1,6,7
  1. 1Center for Mind and Brain, University of California, Davis, Davis, California 95618
  2. 2Institute for Intelligent Systems, University of Memphis, Memphis, Tennessee 38152
  3. 3School of Communication Sciences & Disorders, University of Memphis, Memphis, Tennessee 38152
  4. 4Neuroscience Graduate Group, University of California, Davis, Davis, California 95616
  5. 5Psychology Graduate Group, University of California, Davis, Davis, California 95616
  6. 6Departments of Otolaryngology | Head and Neck Surgery, University of California, Davis, Davis, California 95616
  7. 7Neurobiology, Physiology and Behavior, University of California, Davis, Davis, California 95616
  1. Correspondence should be addressed to Lee M. Miller at leemiller{at}ucdavis.edu.
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Author contributions

  1. Author contributions: D.C.C., K.M., H.B., D.S., and L.M.M. designed research; S.S., B.M.B., and S.D. performed research; S.S., D.C.C., K.M., and B.M.B. analyzed data; S.S., D.C.C., K.M., B.M.B., S.D., D.S., and L.M.M. wrote the paper.

Disclosures

  • L.M.M. is an inventor on intellectual property related to chirped-speech (Cheech) owned by the Regents of the University of California and not presently licensed.

  • This work was supported by the Office of the Assistant Secretary of Defense for Health Affairs through the Congressionally Directed Medical Research Program (CDMRP) Hearing Restoration Research Program (HRRP) under Award Number W81XWH-20-1-0485 (to L.M.M.). Opinions, interpretations, conclusions, and recommendations are those of the author and are not necessarily endorsed by the Department of Defense. This work was also supported by the Child Family Fund for the Center for Mind & Brain (to L.M.M.). We thank members of the University of California, Davis Health audiology and clinical research team for performing initial hearing evaluations of our participants: Dr. Robert Ivory, Au.D., Dr. Mackenzie Quinn, Au.D., Dr. Rachel Krager, Au.D., Dr. Steven Zurawski, Au.D., Dr. Austin Childers, Au.D., Dr. Kimberly Smith, Au.D., Randev Sandhu, and Angela Beliveau. We extend our thanks to Cathleen Chan and Jillian McKie for their assistance in data collection. We are also grateful to Elyse Ehlert and Tiana Smith for their efforts in participant recruitment. We would like to acknowledge Sophie Burstein, Alicia Dye, Reina Itakura, Zachary McNaughton, Ferdous Rahimi, Tyler Statema, Audrey Vargas, and Nina Wade for their insightful discussions and constructive feedback. We give our special thanks to Dr. Chhayakant Patro for providing us with the computerized version of the Trail Making Test. Finally, we sincerely thank the participants of this research study without whom none of this work would be possible. This research is published in remembrance of our team member, lab mate, and friend, Karim Abou Najm.

Funding

  • U.S. Department of Defense (DOD)

    W81XWH-20-1-0485
  • Child Family Fund for the Center for Mind & Brain

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Individual Differences in Cognition and Perception Predict Neural Processing of Speech in Noise for Audiometrically Normal Listeners
Sana Shehabi, Daniel C. Comstock, Kelsey Mankel, Brett M. Bormann, Soukhin Das, Hilary Brodie, Doron Sagiv, Lee M. Miller
eNeuro 18 March 2025, 12 (4) ENEURO.0381-24.2025; DOI: 10.1523/ENEURO.0381-24.2025

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Individual Differences in Cognition and Perception Predict Neural Processing of Speech in Noise for Audiometrically Normal Listeners
Sana Shehabi, Daniel C. Comstock, Kelsey Mankel, Brett M. Bormann, Soukhin Das, Hilary Brodie, Doron Sagiv, Lee M. Miller
eNeuro 18 March 2025, 12 (4) ENEURO.0381-24.2025; DOI: 10.1523/ENEURO.0381-24.2025
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Keywords

  • auditory attention
  • auditory processing
  • cognition
  • event-related potential
  • N1 component
  • speech-in-noise

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