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Research ArticleResearch Article: New Research, Disorders of the Nervous System

Exposure to Acute Psychological Trauma Prior to Blast Neurotrauma Results in Alternative Behavioral Outcomes

Jessica Strickler, Susan Murphy, Kathryn Athanasaw, Natalia Bowyer and Pamela J. VandeVord
eNeuro 17 March 2025, 12 (3) ENEURO.0026-24.2025; https://doi.org/10.1523/ENEURO.0026-24.2025
Jessica Strickler
1Department of Biomedical Engineering and Mechanics, Virginia Tech, Blacksburg, Virginia 24061
2Veterans Affairs Medical Center, Salem, Virginia 24153
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Susan Murphy
1Department of Biomedical Engineering and Mechanics, Virginia Tech, Blacksburg, Virginia 24061
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Kathryn Athanasaw
1Department of Biomedical Engineering and Mechanics, Virginia Tech, Blacksburg, Virginia 24061
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Natalia Bowyer
3School of Neuroscience, Virginia Tech, Blacksburg, Virginia 24061
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Pamela J. VandeVord
1Department of Biomedical Engineering and Mechanics, Virginia Tech, Blacksburg, Virginia 24061
2Veterans Affairs Medical Center, Salem, Virginia 24153
4School of Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, Virginia 24061
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0026-24.2025
PubMed 
40097177
Published By 
Society for Neuroscience
History 
  • Received January 8, 2024
  • Revision received January 30, 2025
  • Accepted February 3, 2025
  • Published online March 17, 2025.
Copyright & Usage 
Copyright © 2025 Strickler et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Jessica Strickler1,2,
  2. Susan Murphy1,
  3. Kathryn Athanasaw1,
  4. Natalia Bowyer3 and
  5. Pamela J. VandeVord1,2,4
  1. 1Department of Biomedical Engineering and Mechanics, Virginia Tech, Blacksburg, Virginia 24061
  2. 2Veterans Affairs Medical Center, Salem, Virginia 24153
  3. 3School of Neuroscience, Virginia Tech, Blacksburg, Virginia 24061
  4. 4School of Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, Virginia 24061
  1. Correspondence should be addressed to Pamela J. VandeVord at pvord{at}vt.edu.
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Author contributions

  1. Author contributions: J.S. and P.J.V. designed research; J.S., S.M., K.A., and N.B. performed research; J.S., K.A., and N.B. analyzed data; J.S. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • We thank Amirah Wright and Caiti-Erin Talty for their assistance with animal handling and Dr. Michelle Olsen and Dr. Timothy Jarome for their guidance and expertise during data analysis and manuscript preparation. This work was supported by the Department of Defense Award No. W81XWH-22-1-1006 (Log #TP210400; to P.J.V.) Opinions, interpretations, conclusions, and recommendations are those of the authors and are not necessarily endorsed by the Department of Defense. In conducting research using animals, the investigator(s) adheres to the laws of the United States and regulations of the Department of Agriculture.

Funding

  • U.S. Department of Defense (DOD)

    W81XWH-22-1-1006

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eneuro: 12 (3)
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Exposure to Acute Psychological Trauma Prior to Blast Neurotrauma Results in Alternative Behavioral Outcomes
Jessica Strickler, Susan Murphy, Kathryn Athanasaw, Natalia Bowyer, Pamela J. VandeVord
eNeuro 17 March 2025, 12 (3) ENEURO.0026-24.2025; DOI: 10.1523/ENEURO.0026-24.2025

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Exposure to Acute Psychological Trauma Prior to Blast Neurotrauma Results in Alternative Behavioral Outcomes
Jessica Strickler, Susan Murphy, Kathryn Athanasaw, Natalia Bowyer, Pamela J. VandeVord
eNeuro 17 March 2025, 12 (3) ENEURO.0026-24.2025; DOI: 10.1523/ENEURO.0026-24.2025
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Keywords

  • anxiety
  • blast TBI
  • depression
  • stress
  • TBI

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