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Research ArticleResearch Article: Confirmation, Cognition and Behavior

Altered Dopamine Signaling in Extinction-Deficient Mice

Ozge Gunduz-Cinar, Eva Maria Fritz, Maya Xia, Elise Van Leer, Nevin Crow, Andrew Holmes and Nicolas Singewald
eNeuro 20 November 2025, 12 (11) ENEURO.0174-25.2025; https://doi.org/10.1523/ENEURO.0174-25.2025
Ozge Gunduz-Cinar
1Laboratory of Behavioral and Genomic Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20852
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  • ORCID record for Ozge Gunduz-Cinar
Eva Maria Fritz
2Department of Pharmacology and Toxicology, University of Innsbruck, Innsbruck 6020, Austria
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Maya Xia
1Laboratory of Behavioral and Genomic Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20852
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Elise Van Leer
1Laboratory of Behavioral and Genomic Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20852
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Nevin Crow
1Laboratory of Behavioral and Genomic Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20852
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Andrew Holmes
1Laboratory of Behavioral and Genomic Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20852
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Nicolas Singewald
2Department of Pharmacology and Toxicology, University of Innsbruck, Innsbruck 6020, Austria
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eneuro: 12 (11)
eNeuro
Vol. 12, Issue 11
November 2025
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Altered Dopamine Signaling in Extinction-Deficient Mice
Ozge Gunduz-Cinar, Eva Maria Fritz, Maya Xia, Elise Van Leer, Nevin Crow, Andrew Holmes, Nicolas Singewald
eNeuro 20 November 2025, 12 (11) ENEURO.0174-25.2025; DOI: 10.1523/ENEURO.0174-25.2025

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Altered Dopamine Signaling in Extinction-Deficient Mice
Ozge Gunduz-Cinar, Eva Maria Fritz, Maya Xia, Elise Van Leer, Nevin Crow, Andrew Holmes, Nicolas Singewald
eNeuro 20 November 2025, 12 (11) ENEURO.0174-25.2025; DOI: 10.1523/ENEURO.0174-25.2025
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Keywords

  • DAT-Cre
  • dopamine
  • fear extinction
  • prediction error

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