Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT

User menu

Search

  • Advanced search
eNeuro
eNeuro

Advanced Search

 

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT
PreviousNext
Research ArticleResearch Article: New Research, Integrative Systems

Repetitive Grooming Behavior Following Aversive Stimulus Coincides with a Decrease in Anterior Hypothalamic Area Activity

Brenton T. Laing, Megan S. Anderson, Aishwarya Jayan, Anika S. Park, Lydia J. Erbaugh, Oscar Solis, Danielle J. Wilson, Michael Michaelides and Yeka Aponte
eNeuro 21 January 2025, 12 (1) ENEURO.0417-24.2024; https://doi.org/10.1523/ENEURO.0417-24.2024
Brenton T. Laing
1Neuronal Circuits and Behavior Section, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224-6823
2Department of BioMolecular Sciences, School of Pharmacy, University of Mississippi, Oxford, Mississippi 38677
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Brenton T. Laing
Megan S. Anderson
1Neuronal Circuits and Behavior Section, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224-6823
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Aishwarya Jayan
1Neuronal Circuits and Behavior Section, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224-6823
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Aishwarya Jayan
Anika S. Park
1Neuronal Circuits and Behavior Section, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224-6823
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lydia J. Erbaugh
1Neuronal Circuits and Behavior Section, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224-6823
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Oscar Solis
3Biobehavioral Imaging and Molecular Neuropsychopharmacology Section, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224-6823
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Danielle J. Wilson
1Neuronal Circuits and Behavior Section, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224-6823
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michael Michaelides
3Biobehavioral Imaging and Molecular Neuropsychopharmacology Section, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224-6823
4Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Michael Michaelides
Yeka Aponte
1Neuronal Circuits and Behavior Section, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224-6823
5The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/ENEURO.0417-24.2024
PubMed 
39837667
Published By 
Society for Neuroscience
History 
  • Received September 24, 2024
  • Revision received December 18, 2024
  • Accepted December 19, 2024
  • Published online January 21, 2025.
Copyright & Usage 
Copyright © 2025 Laing et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Brenton T. Laing1,2,
  2. Megan S. Anderson1,
  3. Aishwarya Jayan1,
  4. Anika S. Park1,
  5. Lydia J. Erbaugh1,
  6. Oscar Solis3,
  7. Danielle J. Wilson1,
  8. Michael Michaelides3,4 and
  9. Yeka Aponte1,5
  1. 1Neuronal Circuits and Behavior Section, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224-6823
  2. 2Department of BioMolecular Sciences, School of Pharmacy, University of Mississippi, Oxford, Mississippi 38677
  3. 3Biobehavioral Imaging and Molecular Neuropsychopharmacology Section, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224-6823
  4. 4Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205
  5. 5The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205
  1. Correspondence should be addressed to Yeka Aponte at yeka.aponte{at}nih.gov.
View Full Text

Author contributions

  1. Author contributions: B.T.L., O.S., M.M., and Y.A. designed research; B.T.L., M.S.A., A.J., A.S.P., O.S., and D.J.W. performed research; B.T.L., M.S.A., A.J., L.J.E., O.S., M.M., and Y.A. analyzed data; B.T.L., O.S., M.M., and Y.A. wrote the paper.

Disclosures

  • M.M. has received research funding from AstraZeneca, Redpin Therapeutics, and Attune Neurosciences. All other authors declare no competing financial interests.

  • We thank C. Lupica and G. Schoenbaum for discussions and comments on the manuscript and S. Sarsfield for figure preparation and manuscript edits. Permission to publish miniscope drawing granted by Doric Lenses.

  • This work was supported by the National Institute on Drug Abuse Intramural Research Program (NIDA IRP; ZIADA000595 and ZIADA000069), US National Institutes of Health (NIH). B.T.L. was supported by the NIH Center on Compulsive Behaviors (CCB).

Funding

  • HHS | NIH | National Institute on Drug Abuse (NIDA)

    ZIADA000595; ZIADA000069

Other Version

  • You are viewing the most recent version of this article.
  • previous version (January 21, 2025).

Online Impact

 

Article usage

Select a custom date range for the past year
E.g., 2025-07-12
to
E.g., 2025-07-12

Article usage: January 2025 to July 2025

AbstractFullPdf
Jan 2025298100191
Feb 202561229121
Mar 20254014249
Apr 20253611938
May 20252211539
Jun 20252411929
Jul 2025153018
Total 2025496854485
Total496854485
Back to top

In this issue

eneuro: 12 (1)
eNeuro
Vol. 12, Issue 1
January 2025
  • Table of Contents
  • Index by author
  • Masthead (PDF)
Email

Thank you for sharing this eNeuro article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Repetitive Grooming Behavior Following Aversive Stimulus Coincides with a Decrease in Anterior Hypothalamic Area Activity
(Your Name) has forwarded a page to you from eNeuro
(Your Name) thought you would be interested in this article in eNeuro.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
Repetitive Grooming Behavior Following Aversive Stimulus Coincides with a Decrease in Anterior Hypothalamic Area Activity
Brenton T. Laing, Megan S. Anderson, Aishwarya Jayan, Anika S. Park, Lydia J. Erbaugh, Oscar Solis, Danielle J. Wilson, Michael Michaelides, Yeka Aponte
eNeuro 21 January 2025, 12 (1) ENEURO.0417-24.2024; DOI: 10.1523/ENEURO.0417-24.2024

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Share
Repetitive Grooming Behavior Following Aversive Stimulus Coincides with a Decrease in Anterior Hypothalamic Area Activity
Brenton T. Laing, Megan S. Anderson, Aishwarya Jayan, Anika S. Park, Lydia J. Erbaugh, Oscar Solis, Danielle J. Wilson, Michael Michaelides, Yeka Aponte
eNeuro 21 January 2025, 12 (1) ENEURO.0417-24.2024; DOI: 10.1523/ENEURO.0417-24.2024
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Significance Statement
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Footnotes
    • References
    • Synthesis
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • anterior hypothalamic area
  • functional imaging
  • optogenetics
  • repetitive grooming behavior
  • ventromedial hypothalamus

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

Research Article: New Research

  • Novel roles for the GPI-anchor cleaving enzyme, GDE2, in hippocampal synaptic morphology and function
  • Upright posture: a singular condition stabilizing sensorimotor coordination
  • Serotonergic signaling governs C. elegans sensory response to conflicting chemosensory stimuli.
Show more Research Article: New Research

Integrative Systems

  • Functional Connectome Correlates of Laterality Preferences: Insights into Hand, Foot, and Eye Dominance across the Lifespan
  • Characteristics of Spontaneous Anterior–Posterior Oscillation-Frequency Convergences in the Alpha Band
  • Alpha-Frequency Stimulation Enhances Synchronization of Alpha Oscillations with Default Mode Network Connectivity
Show more Integrative Systems

Subjects

  • Integrative Systems
  • Home
  • Alerts
  • Follow SFN on BlueSky
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Latest Articles
  • Issue Archive
  • Blog
  • Browse by Topic

Information

  • For Authors
  • For the Media

About

  • About the Journal
  • Editorial Board
  • Privacy Notice
  • Contact
  • Feedback
(eNeuro logo)
(SfN logo)

Copyright © 2025 by the Society for Neuroscience.
eNeuro eISSN: 2373-2822

The ideas and opinions expressed in eNeuro do not necessarily reflect those of SfN or the eNeuro Editorial Board. Publication of an advertisement or other product mention in eNeuro should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in eNeuro.