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Research ArticleResearch Article: New Research, Disorders of the Nervous System

TrkB Agonist (7,8-DHF)-Induced Responses in Dorsal Root Ganglia Neurons Are Decreased after Spinal Cord Injury: Implication for Peripheral Pain Mechanisms

Kyeongran Jang and Sandra M. Garraway
eNeuro 3 January 2025, 12 (1) ENEURO.0219-24.2024; https://doi.org/10.1523/ENEURO.0219-24.2024
Kyeongran Jang
Department of Cell Biology, School of Medicine, Emory University, Atlanta, Georgia 30322
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Sandra M. Garraway
Department of Cell Biology, School of Medicine, Emory University, Atlanta, Georgia 30322
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0219-24.2024
PubMed 
39753357
Published By 
Society for Neuroscience
History 
  • Received May 27, 2024
  • Revision received November 8, 2024
  • Accepted December 4, 2024
  • Published online January 3, 2025.
Copyright & Usage 
Copyright © 2025 Jang and Garraway This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Kyeongran Jang and
  2. Sandra M. Garraway
  1. Department of Cell Biology, School of Medicine, Emory University, Atlanta, Georgia 30322
  1. Correspondence should be addressed to Sandra M. Garraway at smgarraway{at}emory.edu.
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Author contributions

  1. Author contributions: K.J. and S.M.G. designed research; K.J. and S.M.G. performed research; K.J. and S.M.G. analyzed data; K.J. and S.M.G. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by funds provided by National Institute of Neurological Disorders and Stroke (NINDS) Grants #R01NS102850 and #1R21NS116665 to S.M.G. Additional financial support was provided by Emory University Discretionary Funds. We thank Shangrila Parvin and Zaria Herriman for assisting with breeding and post-surgical care of mice.

Funding

  • HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)

    R01NS102850; R21NS116665

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January 2025
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TrkB Agonist (7,8-DHF)-Induced Responses in Dorsal Root Ganglia Neurons Are Decreased after Spinal Cord Injury: Implication for Peripheral Pain Mechanisms
Kyeongran Jang, Sandra M. Garraway
eNeuro 3 January 2025, 12 (1) ENEURO.0219-24.2024; DOI: 10.1523/ENEURO.0219-24.2024

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TrkB Agonist (7,8-DHF)-Induced Responses in Dorsal Root Ganglia Neurons Are Decreased after Spinal Cord Injury: Implication for Peripheral Pain Mechanisms
Kyeongran Jang, Sandra M. Garraway
eNeuro 3 January 2025, 12 (1) ENEURO.0219-24.2024; DOI: 10.1523/ENEURO.0219-24.2024
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Keywords

  • DRG
  • pain
  • peripheral
  • sensory neuron
  • spinal cord injury
  • TrkB signaling

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