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Research ArticleResearch Article: New Research, Cognition and Behavior

Adaptive Changes in Group 2 Metabotropic Glutamate Receptors Underlie the Deficit in Recognition Memory Induced by Methamphetamine in Mice

Carla Letizia Busceti, Luisa Di Menna, Sonia Castaldi, Giovanna D’Errico, Alice Taddeucci, Valeria Bruno, Francesco Fornai, Anna Pittaluga, Giuseppe Battaglia and Ferdinando Nicoletti
eNeuro 5 July 2024, 11 (8) ENEURO.0523-23.2024; https://doi.org/10.1523/ENEURO.0523-23.2024
Carla Letizia Busceti
1Department of Molecular Pathology, IRCCS Neuromed, Pozzilli 86077, Italy
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  • ORCID record for Carla Letizia Busceti
Luisa Di Menna
1Department of Molecular Pathology, IRCCS Neuromed, Pozzilli 86077, Italy
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Sonia Castaldi
2Department of Physiology and Pharmacology, University Sapienza, Roma 00185, Italy
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Giovanna D’Errico
1Department of Molecular Pathology, IRCCS Neuromed, Pozzilli 86077, Italy
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Alice Taddeucci
3Department of Pharmacy, University of Genova, Genova 16148, Italy
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Valeria Bruno
1Department of Molecular Pathology, IRCCS Neuromed, Pozzilli 86077, Italy
2Department of Physiology and Pharmacology, University Sapienza, Roma 00185, Italy
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Francesco Fornai
1Department of Molecular Pathology, IRCCS Neuromed, Pozzilli 86077, Italy
4Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa 56126, Italy
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Anna Pittaluga
3Department of Pharmacy, University of Genova, Genova 16148, Italy
5IRCCS Ospedale Policlinico San Martino, Genova 16145, Italy
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Giuseppe Battaglia
1Department of Molecular Pathology, IRCCS Neuromed, Pozzilli 86077, Italy
2Department of Physiology and Pharmacology, University Sapienza, Roma 00185, Italy
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Ferdinando Nicoletti
1Department of Molecular Pathology, IRCCS Neuromed, Pozzilli 86077, Italy
2Department of Physiology and Pharmacology, University Sapienza, Roma 00185, Italy
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0523-23.2024
PubMed 
38969501
Published By 
Society for Neuroscience
History 
  • Received December 11, 2023
  • Revision received May 27, 2024
  • Accepted June 4, 2024
  • Published online July 5, 2024.
Copyright & Usage 
Copyright © 2024 Busceti et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Carla Letizia Busceti1,
  2. Luisa Di Menna1,
  3. Sonia Castaldi2,
  4. Giovanna D’Errico1,
  5. Alice Taddeucci3,
  6. Valeria Bruno1,2,
  7. Francesco Fornai1,4,
  8. Anna Pittaluga3,5,
  9. Giuseppe Battaglia1,2,* and
  10. Ferdinando Nicoletti1,2,*
  1. 1Department of Molecular Pathology, IRCCS Neuromed, Pozzilli 86077, Italy
  2. 2Department of Physiology and Pharmacology, University Sapienza, Roma 00185, Italy
  3. 3Department of Pharmacy, University of Genova, Genova 16148, Italy
  4. 4Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa 56126, Italy
  5. 5IRCCS Ospedale Policlinico San Martino, Genova 16145, Italy
  1. Correspondence should be addressed to Ferdinando Nicoletti at nicoletti{at}neuromed.it or ferdinando.nicoletti{at}uniroma.it.
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Author contributions

  1. Author contributions: C.L.B., V.B., F.F., A.P., G.B., and F.N. designed research; C.L.B., L.D.M., S.C., G.D., and A.T. performed research; C.L.B. analyzed data; C.L.B., V.B., F.F., A.P., G.B., and F.N. wrote the paper.

Disclosures

  • The authors declare no conflict of interests.

  • This research was supported by the Italian Ministry of Health (Ricerca Corrente 2024).

  • ↵*G.B. and F.N. contributed equally to this work.

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Jul 20243620123
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Adaptive Changes in Group 2 Metabotropic Glutamate Receptors Underlie the Deficit in Recognition Memory Induced by Methamphetamine in Mice
Carla Letizia Busceti, Luisa Di Menna, Sonia Castaldi, Giovanna D’Errico, Alice Taddeucci, Valeria Bruno, Francesco Fornai, Anna Pittaluga, Giuseppe Battaglia, Ferdinando Nicoletti
eNeuro 5 July 2024, 11 (8) ENEURO.0523-23.2024; DOI: 10.1523/ENEURO.0523-23.2024

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Adaptive Changes in Group 2 Metabotropic Glutamate Receptors Underlie the Deficit in Recognition Memory Induced by Methamphetamine in Mice
Carla Letizia Busceti, Luisa Di Menna, Sonia Castaldi, Giovanna D’Errico, Alice Taddeucci, Valeria Bruno, Francesco Fornai, Anna Pittaluga, Giuseppe Battaglia, Ferdinando Nicoletti
eNeuro 5 July 2024, 11 (8) ENEURO.0523-23.2024; DOI: 10.1523/ENEURO.0523-23.2024
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Keywords

  • AGS3
  • cognitive dysfunction
  • glutamate release
  • metabotropic glutamate receptors
  • prefrontal cortex
  • Rab3A

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