Article Information
- Received November 21, 2023
- Revision received April 30, 2024
- Accepted May 23, 2024
- Published online June 12, 2024.
Author Information
- Veronica M. Hong1,2,
- Avaneesh D. Rade1,
- Shen M. Yan1,
- Amulya Bhaskara1,
- Muhammad Saad Yousuf1,2,
- Min Chen3,
- Stephen F. Martin4,
- Daniel J. Liebl5,
- Theodore J. Price1,2 and
- Benedict J. Kolber1,2
- 1Department of Neuroscience, School of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, Texas 75080
- 2Center for Advanced Pain Studies, School of Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, Texas 75080
- 3Department of Mathematical Sciences, School of Natural Sciences and Mathematics, University of Texas at Dallas, Richardson, Texas 75080
- 4Department of Chemistry, University of Texas at Austin, Austin, Texas 78712
- 5Department of Neurosurgery, University of Miami, Miller School of Medicine, Miami, Florida 33146
- Correspondence should be addressed to Benedict J. Kolber at benedict.kolber{at}utdallas.edu.
Author contributions
Author contributions: V.M.H., M.S.Y., S.F.M., T.J.P., and B.J.K. designed research; V.M.H., A.D.R., S.M.Y., A.B., M.S.Y., and B.J.K. performed research; S.F.M. and D.J.L. contributed unpublished reagents/analytic tools; V.M.H., A.D.R., S.M.Y., and M.C. analyzed data; V.M.H., A.D.R., T.J.P., and B.J.K. wrote the paper.
Disclosures
The authors declare the following financial relationships. M.S.Y., S.F.M., and T.J.P. are cofounders of NuvoNuro which is focused on the development of ligands for sigma-2 receptor/TMEM97. No experimental compounds from the company were used in the present study.
We thank Dr. Joe Lombardo for technical assistance with imaging, Dr. Anny Treat for conducting pilot experiments, Tarik Ehsan for his assistance with animal behaviors, and Mursal Hussein for colony and resource management. This work was supported by the National Institutes of Health F31NS129269 (V.M.H.), R01DK115478 (B.J.K.), and R61NS127271 (B.J.K.) and The Eugene McDermott Foundation (V.M.H.).
Funding
HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)
F31NS129269; R61NS127271HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
R01DK115478Eugene McDermott Foundation (The Eugene McDermott Foundation)
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