Article Information
- Received October 24, 2023
- Revision received March 20, 2024
- Accepted April 18, 2024
- Published online June 13, 2024.
Author Information
- Jamie C. Moffa1,2,
- India N. Bland1,
- Jessica R. Tooley1,3,
- Vani Kalyanaraman1,
- Monique Heitmeier1,
- Meaghan C. Creed1,4 and
- Bryan A. Copits1
- 1Washington University Pain Center, Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri 63110
- 2Washington University Medical Scientist Training Program, Washington University School of Medicine, St. Louis, Missouri 63110
- 3Washington University Division of Biological and Behavioral Sciences, Washington University School of Medicine, St. Louis, Missouri 63110
- 4Departments of Neuroscience, Psychiatry, and Biomedical Engineering, Washington University School of Medicine, St. Louis, Missouri 63110
- Correspondence should be addressed to Bryan Copits at bcopits{at}wustl.edu.
Author contributions
Author contributions: J.C.M., M.C.C., and B.A.C. designed research; J.C.M., I.N.B., J.R.T., M.C.C., and B.A.C. performed research; J.C.M., I.N.B., and B.A.C. analyzed data; V.K. and M.H. contributed unpublished reagents/analytic tools; J.C.M. and B.A.C. wrote the paper.
Disclosures
The authors declare no competing financial interests.
We thank all the members of the lab for their helpful discussions and feedback, Alexxai Kravitz for his feedback on our photometry experiment design, Alex Legaria for helping with photometry analysis, Dr. Mingjie Li at the Hope Center Viral Vectors Core at Washington University for assisting in establishing viral vector purifications, the Genome Engineering & Stem Cell Center (GESC@MGI, RRID: SCR_023243) at the Washington University in St. Louis for reagent validation services, and Vera Thornton for consulting on statistical analyses. AAV PHP.S viruses were purchased from the UNC Neuroscience Center/BRAIN Initiative NeuroTools Core (U24 NS124025 to Kimberly Ritola). This work was supported by NIH R01s NS130046 (B.A.C.), DA049924 (M.C.C.), and DA058755 (M.C.C.) and internal funds from the McDonnell Center for Systems Neuroscience (B.A.C.).
Funding
HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)
NS130046HHS | NIH | National Institute on Drug Abuse (NIDA)
DA049924; DA058755WashU | McDonnell Center for Systems Neuroscience
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