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Research ArticleResearch Article: New Research, Sensory and Motor Systems

A Vestibular Challenge Combined with Calcitonin Gene-Related Peptide (CGRP) Promotes Anxiety-Like Behaviors

Shafaqat M. Rahman, Catherine Hauser, Stefanie Faucher, Elana Fine and Anne E. Luebke
eNeuro 12 July 2024, 11 (7) ENEURO.0270-23.2024; https://doi.org/10.1523/ENEURO.0270-23.2024
Shafaqat M. Rahman
1Department of Biomedical Engineering, University of Rochester, Rochester, New York 14627
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Catherine Hauser
1Department of Biomedical Engineering, University of Rochester, Rochester, New York 14627
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Stefanie Faucher
1Department of Biomedical Engineering, University of Rochester, Rochester, New York 14627
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Elana Fine
1Department of Biomedical Engineering, University of Rochester, Rochester, New York 14627
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Anne E. Luebke
1Department of Biomedical Engineering, University of Rochester, Rochester, New York 14627
2Department of Neuroscience, Del Monte Institute of Neuroscience, University of Rochester Medical Center, Rochester, New York 14642
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0270-23.2024
PubMed 
38997144
Published By 
Society for Neuroscience
History 
  • Received August 1, 2023
  • Revision received April 23, 2024
  • Accepted April 25, 2024
  • Published online July 12, 2024.
Copyright & Usage 
Copyright © 2024 Rahman et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Shafaqat M. Rahman1,
  2. Catherine Hauser1,
  3. Stefanie Faucher1,
  4. Elana Fine1 and
  5. Anne E. Luebke1,2
  1. 1Department of Biomedical Engineering, University of Rochester, Rochester, New York 14627
  2. 2Department of Neuroscience, Del Monte Institute of Neuroscience, University of Rochester Medical Center, Rochester, New York 14642
  1. Correspondence should be addressed to Anne E. Luebke at aluebke{at}ur.rochester.edu.
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Author contributions

  1. Author contributions: A.E.L. designed research; S.M.R., C.H., S.F., E.F., and A.E.L. performed research; S.M.R., C.H., S.F., E.F., and A.E.L. analyzed data; S.M.R. and A.E.L. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • We acknowledge Travis Kovitz, Katharine Bachmann, and the Behavioral Sciences Facility Core at the University of Rochester for data collection of elevated plus maze experiments. All figures created with BioRender.com. This work was fully supported by the National Institutes of Health (Grant R01DC017261).

Funding

  • HHS | NIH | National Institute on Deafness and Other Communication Disorders (NIDCD)

    R01DC017261

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July 2024
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A Vestibular Challenge Combined with Calcitonin Gene-Related Peptide (CGRP) Promotes Anxiety-Like Behaviors
Shafaqat M. Rahman, Catherine Hauser, Stefanie Faucher, Elana Fine, Anne E. Luebke
eNeuro 12 July 2024, 11 (7) ENEURO.0270-23.2024; DOI: 10.1523/ENEURO.0270-23.2024

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A Vestibular Challenge Combined with Calcitonin Gene-Related Peptide (CGRP) Promotes Anxiety-Like Behaviors
Shafaqat M. Rahman, Catherine Hauser, Stefanie Faucher, Elana Fine, Anne E. Luebke
eNeuro 12 July 2024, 11 (7) ENEURO.0270-23.2024; DOI: 10.1523/ENEURO.0270-23.2024
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Keywords

  • anxiety
  • calcitonin gene-related peptide (CGRP)
  • mouse models
  • rotarod and elevated plus maze
  • vestibular
  • vestibular migraine

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